Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Ligand_(biochemistry)> ?p ?o }
- Ligand_(biochemistry) abstract "In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. In protein-ligand binding, the ligand is usually a molecule which produces a signal by binding to a site on a target protein. The binding typically results in a change of conformation of the target protein. In DNA-ligand binding studies, the ligand can be a small molecule, ion, or protein which binds to the DNA double helix. The relationship between ligand and binding partner is a function of charge, hydrophobicity, and molecular structure. The instance of binding occurs over an infinitesimal range of time and space, so the rate constant is usually a very small number.Binding occurs by intermolecular forces, such as ionic bonds, hydrogen bonds and Van der Waals forces. The association of docking is actually reversible through dissociation. Measurably irreversible covalent bonding between a ligand and target molecule is atypical in biological systems. In contrast to the definition of ligand in metalorganic and inorganic chemistry, in biochemistry it is ambiguous whether the ligand generally binds at a metal site, as is the case in hemoglobin. In general, the interpretation of ligand is contextual with regards to what sort of binding has been observed. The etymology stems from ligare, which means 'to bind'.Ligand binding to a receptor protein alters the chemical conformation by affecting the three-dimensional shape orientation. The conformation of a receptor protein composes the functional state. Ligands include substrates, inhibitors, activators, and neurotransmitters. The rate of binding is called affinity, and this measurement typifies a tendency or strength of the effect. Binding affinity is actualized not only by host-guest interactions, but also by solvent effects that can play a dominant, steric role which drives non-covalent binding in solution. The solvent provides a chemical environment for the ligand and receptor to adapt, and thus accept or reject each other as partners.Radioligands are radioisotope labeled compounds are used in vivo as tracers in PET studies and for in vitro binding studies.".
- Ligand_(biochemistry) thumbnail Myoglobin_and_heme.png?width=300.
- Ligand_(biochemistry) wikiPageExternalLink www.bindingdb.org.
- Ligand_(biochemistry) wikiPageExternalLink BioLiP.
- Ligand_(biochemistry) wikiPageID "2202422".
- Ligand_(biochemistry) wikiPageLength "14066".
- Ligand_(biochemistry) wikiPageOutDegree "73".
- Ligand_(biochemistry) wikiPageRevisionID "708368223".
- Ligand_(biochemistry) wikiPageWikiLink Adverse_effect.
- Ligand_(biochemistry) wikiPageWikiLink Agonist.
- Ligand_(biochemistry) wikiPageWikiLink Allosteric_regulation.
- Ligand_(biochemistry) wikiPageWikiLink Binding_site.
- Ligand_(biochemistry) wikiPageWikiLink Biochemistry.
- Ligand_(biochemistry) wikiPageWikiLink Biomolecule.
- Ligand_(biochemistry) wikiPageWikiLink Carbon_monoxide.
- Ligand_(biochemistry) wikiPageWikiLink Carbon_monoxide_poisoning.
- Ligand_(biochemistry) wikiPageWikiLink Category:Biomolecules.
- Ligand_(biochemistry) wikiPageWikiLink Category:Cell_signaling.
- Ligand_(biochemistry) wikiPageWikiLink Category:Chemical_bonding.
- Ligand_(biochemistry) wikiPageWikiLink Category:Ligands.
- Ligand_(biochemistry) wikiPageWikiLink Category:Proteins.
- Ligand_(biochemistry) wikiPageWikiLink Concentration.
- Ligand_(biochemistry) wikiPageWikiLink Conformational_isomerism.
- Ligand_(biochemistry) wikiPageWikiLink Coordination_complex.
- Ligand_(biochemistry) wikiPageWikiLink Covalent_bond.
- Ligand_(biochemistry) wikiPageWikiLink DNA-binding_protein.
- Ligand_(biochemistry) wikiPageWikiLink Dissociation_constant.
- Ligand_(biochemistry) wikiPageWikiLink Docking@Home.
- Ligand_(biochemistry) wikiPageWikiLink Docking_(molecular).
- Ligand_(biochemistry) wikiPageWikiLink Drug.
- Ligand_(biochemistry) wikiPageWikiLink Dual-polarization_interferometry.
- Ligand_(biochemistry) wikiPageWikiLink Enzyme.
- Ligand_(biochemistry) wikiPageWikiLink Enzyme_activator.
- Ligand_(biochemistry) wikiPageWikiLink Enzyme_inhibitor.
- Ligand_(biochemistry) wikiPageWikiLink GPCR_oligomer.
- Ligand_(biochemistry) wikiPageWikiLink GPUGRID.net.
- Ligand_(biochemistry) wikiPageWikiLink Hemoglobin.
- Ligand_(biochemistry) wikiPageWikiLink Host–guest_chemistry.
- Ligand_(biochemistry) wikiPageWikiLink Hydrogen_bond.
- Ligand_(biochemistry) wikiPageWikiLink IC50.
- Ligand_(biochemistry) wikiPageWikiLink In_vitro.
- Ligand_(biochemistry) wikiPageWikiLink In_vivo.
- Ligand_(biochemistry) wikiPageWikiLink Inorganic_chemistry.
- Ligand_(biochemistry) wikiPageWikiLink Intermolecular_force.
- Ligand_(biochemistry) wikiPageWikiLink Inverse_agonist.
- Ligand_(biochemistry) wikiPageWikiLink Ionic_bonding.
- Ligand_(biochemistry) wikiPageWikiLink Isotopic_labeling.
- Ligand_(biochemistry) wikiPageWikiLink Ki_Database.
- Ligand_(biochemistry) wikiPageWikiLink Ligand.
- Ligand_(biochemistry) wikiPageWikiLink Ligand-gated_ion_channel.
- Ligand_(biochemistry) wikiPageWikiLink Lipinskis_rule_of_five.
- Ligand_(biochemistry) wikiPageWikiLink Metal.
- Ligand_(biochemistry) wikiPageWikiLink Metalorganics.
- Ligand_(biochemistry) wikiPageWikiLink Microscale_thermophoresis.
- Ligand_(biochemistry) wikiPageWikiLink Nano-.
- Ligand_(biochemistry) wikiPageWikiLink Neurotransmitter.
- Ligand_(biochemistry) wikiPageWikiLink Nucleic_acid_double_helix.
- Ligand_(biochemistry) wikiPageWikiLink Oxygen.
- Ligand_(biochemistry) wikiPageWikiLink Partition_function_(statistical_mechanics).
- Ligand_(biochemistry) wikiPageWikiLink Pharmacology.
- Ligand_(biochemistry) wikiPageWikiLink Positron_emission_tomography.
- Ligand_(biochemistry) wikiPageWikiLink Protein.
- Ligand_(biochemistry) wikiPageWikiLink Radioactive_tracer.
- Ligand_(biochemistry) wikiPageWikiLink Radioligand.
- Ligand_(biochemistry) wikiPageWikiLink Radionuclide.
- Ligand_(biochemistry) wikiPageWikiLink Receptor_(biochemistry).
- Ligand_(biochemistry) wikiPageWikiLink Receptor_antagonist.
- Ligand_(biochemistry) wikiPageWikiLink Schild_regression.
- Ligand_(biochemistry) wikiPageWikiLink Statistical_mechanics.
- Ligand_(biochemistry) wikiPageWikiLink Steric_effects.
- Ligand_(biochemistry) wikiPageWikiLink Substrate_(chemistry).
- Ligand_(biochemistry) wikiPageWikiLink Surface_plasmon_resonance.
- Ligand_(biochemistry) wikiPageWikiLink Van_der_Waals_force.
- Ligand_(biochemistry) wikiPageWikiLink File:Agonist_2.png.
- Ligand_(biochemistry) wikiPageWikiLink File:Agonists_v2.png.
- Ligand_(biochemistry) wikiPageWikiLink File:Myoglobin_and_heme.png.
- Ligand_(biochemistry) wikiPageWikiLinkText ""privileged scaffold"".
- Ligand_(biochemistry) wikiPageWikiLinkText "Affinity".
- Ligand_(biochemistry) wikiPageWikiLinkText "Bivalent ligand".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand (biochemistry)".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand (biochemistry)#Privileged scaffold".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand (biochemistry)#Receptor binding affinity".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand (biochemistry)#Receptor.2Fligand binding affinity".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand (biochemistry)#Receptor/ligand binding affinity".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand (biochemistry)#Selective and non-selective".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand (biochemistry)#binding affinity".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligand-binding".
- Ligand_(biochemistry) wikiPageWikiLinkText "Ligands".
- Ligand_(biochemistry) wikiPageWikiLinkText "affinity".
- Ligand_(biochemistry) wikiPageWikiLinkText "androgen binding affinity or retention".
- Ligand_(biochemistry) wikiPageWikiLinkText "binding affinities".
- Ligand_(biochemistry) wikiPageWikiLinkText "binding affinity".
- Ligand_(biochemistry) wikiPageWikiLinkText "binds to".
- Ligand_(biochemistry) wikiPageWikiLinkText "endogenous ligand".
- Ligand_(biochemistry) wikiPageWikiLinkText "endogenous protein".
- Ligand_(biochemistry) wikiPageWikiLinkText "ligand (biochemistry)".
- Ligand_(biochemistry) wikiPageWikiLinkText "ligand binding affinity and specificity".
- Ligand_(biochemistry) wikiPageWikiLinkText "ligand binding".
- Ligand_(biochemistry) wikiPageWikiLinkText "ligand molecule".