Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Lethal_white_syndrome> ?p ?o }
- Lethal_white_syndrome abstract "Lethal white syndrome (LWS), also called overo lethal white syndrome (OLWS), lethal white overo (LWO), and overo lethal white foal syndrome (OLWFS), is an autosomal genetic disorder most prevalent in the American Paint Horse. Affected foals are born after the full 11-month gestation and externally appear normal, though they have all-white or nearly all-white coats and blue eyes. However, internally, these foals have a nonfunctioning colon. Within a few hours, signs of colic appear; affected foals die within a few days. Because the death is often painful, such foals often are humanely euthanized once identified. The disease is particularly devastating because foals are born seemingly healthy after being carried to full term.The disease has a similar etiology to Hirschsprung's disease in humans. A mutation in the middle of the endothelin receptor type B (EDNRB) gene causes lethal white syndrome when homozygous. Carriers, who are heterozygous — that is, have one copy of the mutated allele, but themselves are healthy — can now be reliably identified with a DNA test. Both parents must be carriers of one copy of the LWS allele in order for an affected foal to be born.Horses that are heterozygous for the gene that causes lethal white syndrome often exhibit a spotted coat color pattern commonly known as \"frame\" or \"frame overo.\" Coat color alone does not always indicate the presence of LWS or carrier status, however. The frame pattern may be minimally expressed or masked by other spotting patterns. There also are different genetic mechanisms which produce healthy white foals and have no connection to LWS; another reason for genetic testing of potential breeding stock. Though there is no treatment or cure for LWS foals, a white foal without LWS that appears ill may have a treatable condition.".
- Lethal_white_syndrome wikiPageID "653410".
- Lethal_white_syndrome wikiPageLength "34353".
- Lethal_white_syndrome wikiPageOutDegree "116".
- Lethal_white_syndrome wikiPageRevisionID "673013547".
- Lethal_white_syndrome wikiPageWikiLink Allele.
- Lethal_white_syndrome wikiPageWikiLink American_Paint_Horse.
- Lethal_white_syndrome wikiPageWikiLink American_Paint_Horse_Association.
- Lethal_white_syndrome wikiPageWikiLink American_Quarter_Horse.
- Lethal_white_syndrome wikiPageWikiLink Animal_euthanasia.
- Lethal_white_syndrome wikiPageWikiLink Appaloosa.
- Lethal_white_syndrome wikiPageWikiLink Autopsy.
- Lethal_white_syndrome wikiPageWikiLink Autosome.
- Lethal_white_syndrome wikiPageWikiLink Category:Genetic_disorders_with_no_OMIM.
- Lethal_white_syndrome wikiPageWikiLink Category:Horse_diseases.
- Lethal_white_syndrome wikiPageWikiLink Cecum.
- Lethal_white_syndrome wikiPageWikiLink Champagne_gene.
- Lethal_white_syndrome wikiPageWikiLink Cream_gene.
- Lethal_white_syndrome wikiPageWikiLink Cropout.
- Lethal_white_syndrome wikiPageWikiLink DNA.
- Lethal_white_syndrome wikiPageWikiLink DNA_repair.
- Lethal_white_syndrome wikiPageWikiLink Dilution_gene.
- Lethal_white_syndrome wikiPageWikiLink Dominance_(genetics).
- Lethal_white_syndrome wikiPageWikiLink Dominant_white.
- Lethal_white_syndrome wikiPageWikiLink Endothelin_receptor_type_B.
- Lethal_white_syndrome wikiPageWikiLink Enema.
- Lethal_white_syndrome wikiPageWikiLink Epistasis.
- Lethal_white_syndrome wikiPageWikiLink Equine_anatomy.
- Lethal_white_syndrome wikiPageWikiLink Equine_coat_color.
- Lethal_white_syndrome wikiPageWikiLink Equine_coat_color_genetics.
- Lethal_white_syndrome wikiPageWikiLink Etiology.
- Lethal_white_syndrome wikiPageWikiLink Feces.
- Lethal_white_syndrome wikiPageWikiLink Foal.
- Lethal_white_syndrome wikiPageWikiLink Ganglion.
- Lethal_white_syndrome wikiPageWikiLink Gastrointestinal_tract.
- Lethal_white_syndrome wikiPageWikiLink Gene.
- Lethal_white_syndrome wikiPageWikiLink Genetic_carrier.
- Lethal_white_syndrome wikiPageWikiLink Genetic_disorder.
- Lethal_white_syndrome wikiPageWikiLink Genetic_testing.
- Lethal_white_syndrome wikiPageWikiLink Gestation.
- Lethal_white_syndrome wikiPageWikiLink Hirschsprungs_disease.
- Lethal_white_syndrome wikiPageWikiLink Horse_colic.
- Lethal_white_syndrome wikiPageWikiLink Horse_markings.
- Lethal_white_syndrome wikiPageWikiLink Human_gastrointestinal_tract.
- Lethal_white_syndrome wikiPageWikiLink Isoleucine.
- Lethal_white_syndrome wikiPageWikiLink Large_intestine.
- Lethal_white_syndrome wikiPageWikiLink Lavender_Foal_Syndrome.
- Lethal_white_syndrome wikiPageWikiLink Lysine.
- Lethal_white_syndrome wikiPageWikiLink Meconium.
- Lethal_white_syndrome wikiPageWikiLink Melanocyte.
- Lethal_white_syndrome wikiPageWikiLink Miniature_horse.
- Lethal_white_syndrome wikiPageWikiLink Misnomer.
- Lethal_white_syndrome wikiPageWikiLink Molecular_biology.
- Lethal_white_syndrome wikiPageWikiLink Morgan_horse.
- Lethal_white_syndrome wikiPageWikiLink Mustang.
- Lethal_white_syndrome wikiPageWikiLink Neural_crest.
- Lethal_white_syndrome wikiPageWikiLink Neuron.
- Lethal_white_syndrome wikiPageWikiLink North_America.
- Lethal_white_syndrome wikiPageWikiLink Overo.
- Lethal_white_syndrome wikiPageWikiLink Pearl_gene.
- Lethal_white_syndrome wikiPageWikiLink Penetrance.
- Lethal_white_syndrome wikiPageWikiLink Phenotype.
- Lethal_white_syndrome wikiPageWikiLink Pinto_horse.
- Lethal_white_syndrome wikiPageWikiLink Pleiotropy.
- Lethal_white_syndrome wikiPageWikiLink Polymorphism_(biology).
- Lethal_white_syndrome wikiPageWikiLink Protein.
- Lethal_white_syndrome wikiPageWikiLink Rectum.
- Lethal_white_syndrome wikiPageWikiLink Regulator_gene.
- Lethal_white_syndrome wikiPageWikiLink Sabino_horse.
- Lethal_white_syndrome wikiPageWikiLink Splashed_white.
- Lethal_white_syndrome wikiPageWikiLink Stem_cell.
- Lethal_white_syndrome wikiPageWikiLink Tennessee_Walking_Horse.
- Lethal_white_syndrome wikiPageWikiLink Thoroughbred.
- Lethal_white_syndrome wikiPageWikiLink Tobiano.
- Lethal_white_syndrome wikiPageWikiLink Tovero.
- Lethal_white_syndrome wikiPageWikiLink Waardenburg_syndrome.
- Lethal_white_syndrome wikiPageWikiLink White_(horse).
- Lethal_white_syndrome wikiPageWikiLink Zygosity.
- Lethal_white_syndrome wikiPageWikiLink File:Creamwildponyfilly.jpg.
- Lethal_white_syndrome wikiPageWikiLink File:Grazing_paints.jpg.
- Lethal_white_syndrome wikiPageWikiLink File:SabinoTestedNegforOLWS.jpg.
- Lethal_white_syndrome wikiPageWikiLink File:Yukichan_20080427_001.jpg.
- Lethal_white_syndrome wikiPageWikiLinkText "Frame".
- Lethal_white_syndrome wikiPageWikiLinkText "Lethal white syndrome".
- Lethal_white_syndrome wikiPageWikiLinkText "frame overo".
- Lethal_white_syndrome wikiPageWikiLinkText "frame".
- Lethal_white_syndrome wikiPageWikiLinkText "lethal white syndrome".
- Lethal_white_syndrome wikiPageWikiLinkText "lethal white".
- Lethal_white_syndrome wikiPageUsesTemplate Template:Citation_needed.
- Lethal_white_syndrome wikiPageUsesTemplate Template:Main.
- Lethal_white_syndrome wikiPageUsesTemplate Template:Reflist.
- Lethal_white_syndrome wikiPageUsesTemplate Template:See_also.
- Lethal_white_syndrome subject Category:Genetic_disorders_with_no_OMIM.
- Lethal_white_syndrome subject Category:Horse_diseases.
- Lethal_white_syndrome hypernym Disorder.
- Lethal_white_syndrome type Disease.
- Lethal_white_syndrome type Disorder.
- Lethal_white_syndrome type Redirect.
- Lethal_white_syndrome type Thing.
- Lethal_white_syndrome comment "Lethal white syndrome (LWS), also called overo lethal white syndrome (OLWS), lethal white overo (LWO), and overo lethal white foal syndrome (OLWFS), is an autosomal genetic disorder most prevalent in the American Paint Horse. Affected foals are born after the full 11-month gestation and externally appear normal, though they have all-white or nearly all-white coats and blue eyes. However, internally, these foals have a nonfunctioning colon.".