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- Latex_fixation_test abstract "A latex fixation test, also called a latex agglutination assay or test (LA assay or test), is an assay used clinically in the identification and typing of many important microorganisms. These tests use the patient's antigen-antibody immune response. This response occurs when the body detects a pathogen and forms an antibody specific to an identified antigen (a protein configuration) present on the surface of the pathogen. Agglutination tests, specific to a variety of pathogens, can be designed and manufactured for clinicians by coating microbeads of latex with pathogen-specific antigens or antibodies. In performing a test, laboratory clinicians will mix a patient's cerebrospinal fluid, serum or urine with the coated latex particles in serial dilutions with normal saline (important to avoid the prozone effect) and observe for agglutination (clumping). Agglutination of the beads in any of the dilutions is considered a positive result, confirming either (1) that the patient's body has produced the pathogen-specific antibody (if the test supplied the antigen) or (2) that the specimen contains the pathogen's antigen (if the test supplied the antibody). Instances of cross-reactivity (where the antibody sticks to another antigen besides the antigen of interest) can lead to confusing results.Agglutination techniques are used to detect antibodies produced in response to a variety of viruses and bacteria, as well as autoantibodies, which are produced against the self in autoimmune diseasees. For example, assays exist for rubella virus, rotavirus, and rheumatoid factor, and there is an excellent LA test for cryptococcus. Agglutination techniques are also used in definitive diagnosis of group A streptococcal infection.".
- Latex_fixation_test wikiPageExternalLink 003334.htm.
- Latex_fixation_test wikiPageID "11531277".
- Latex_fixation_test wikiPageLength "2883".
- Latex_fixation_test wikiPageOutDegree "29".
- Latex_fixation_test wikiPageRevisionID "706917774".
- Latex_fixation_test wikiPageWikiLink Agglutination_(biology).
- Latex_fixation_test wikiPageWikiLink Antibody.
- Latex_fixation_test wikiPageWikiLink Antigen.
- Latex_fixation_test wikiPageWikiLink Assay.
- Latex_fixation_test wikiPageWikiLink Autoantibody.
- Latex_fixation_test wikiPageWikiLink Autoimmune_disease.
- Latex_fixation_test wikiPageWikiLink Bacteria.
- Latex_fixation_test wikiPageWikiLink Category:Blood_tests.
- Latex_fixation_test wikiPageWikiLink Category:Immunologic_tests.
- Latex_fixation_test wikiPageWikiLink Category:Medical_tests.
- Latex_fixation_test wikiPageWikiLink Cerebrospinal_fluid.
- Latex_fixation_test wikiPageWikiLink Cross-reactivity.
- Latex_fixation_test wikiPageWikiLink Cryptococcus.
- Latex_fixation_test wikiPageWikiLink Group_A_streptococcal_infection.
- Latex_fixation_test wikiPageWikiLink Hook_effect.
- Latex_fixation_test wikiPageWikiLink Microbead.
- Latex_fixation_test wikiPageWikiLink Microorganism.
- Latex_fixation_test wikiPageWikiLink Natural_rubber.
- Latex_fixation_test wikiPageWikiLink Pathogen.
- Latex_fixation_test wikiPageWikiLink Rheumatoid_factor.
- Latex_fixation_test wikiPageWikiLink Rotavirus.
- Latex_fixation_test wikiPageWikiLink Rubella_virus.
- Latex_fixation_test wikiPageWikiLink Saline_(medicine).
- Latex_fixation_test wikiPageWikiLink Serial_dilution.
- Latex_fixation_test wikiPageWikiLink Serotype.
- Latex_fixation_test wikiPageWikiLink Serum_(blood).
- Latex_fixation_test wikiPageWikiLink Urine.
- Latex_fixation_test wikiPageWikiLink Virus.
- Latex_fixation_test wikiPageWikiLink Visceral_leishmaniasis.
- Latex_fixation_test wikiPageWikiLinkText "Latex fixation test".
- Latex_fixation_test wikiPageWikiLinkText "latex agglutination".
- Latex_fixation_test wikiPageWikiLinkText "latex fixation test".
- Latex_fixation_test medlineplus "3334".
- Latex_fixation_test meshid "D007841".
- Latex_fixation_test name "Latex fixation test".
- Latex_fixation_test wikiPageUsesTemplate Template:Cite_journal.
- Latex_fixation_test wikiPageUsesTemplate Template:Immunologic_techniques_and_tests.
- Latex_fixation_test wikiPageUsesTemplate Template:Immunology-stub.
- Latex_fixation_test wikiPageUsesTemplate Template:Infobox_diagnostic.
- Latex_fixation_test wikiPageUsesTemplate Template:MeshName.
- Latex_fixation_test wikiPageUsesTemplate Template:More_footnotes.
- Latex_fixation_test wikiPageUsesTemplate Template:Reflist.
- Latex_fixation_test subject Category:Blood_tests.
- Latex_fixation_test subject Category:Immunologic_tests.
- Latex_fixation_test subject Category:Medical_tests.
- Latex_fixation_test hypernym Assay.
- Latex_fixation_test type Redirect.
- Latex_fixation_test comment "A latex fixation test, also called a latex agglutination assay or test (LA assay or test), is an assay used clinically in the identification and typing of many important microorganisms. These tests use the patient's antigen-antibody immune response. This response occurs when the body detects a pathogen and forms an antibody specific to an identified antigen (a protein configuration) present on the surface of the pathogen.".
- Latex_fixation_test label "Latex fixation test".
- Latex_fixation_test sameAs Q11795895.
- Latex_fixation_test sameAs Test_di_agglutinazione_al_lattice.
- Latex_fixation_test sameAs Odczyn_lateksowy.
- Latex_fixation_test sameAs m.02rg_tc.
- Latex_fixation_test sameAs Q11795895.
- Latex_fixation_test wasDerivedFrom Latex_fixation_test?oldid=706917774.
- Latex_fixation_test isPrimaryTopicOf Latex_fixation_test.