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- Laminin_111 abstract "One of the first laminin isoforms to be discovered (and named accordingly so) was laminin–1, more accurately denoted as laminin–111. The “111” identifies the isoform's chain composition of α1β1γ1. The distribution of the different laminin isoforms is tissue-specific. Laminin–111 is predominantly expressed in the embryonic epithelium, but can also be found in some adult epithelium such as the kidney, liver, testis, ovaries, and brain blood vessels. Different levels of expression of α chains have a large influence on the differential expression of laminin, thereby determining the isoform produced. From studying a mouse model, it was found that transcription factors present in the parietal endoderm regulate the expression of the α1 and large amounts of laminin-111 are produced. The large amounts of synthesized laminin–111 contribute to the formation of Reichert’s membrane, a thick extra-embryonic basement membrane. When the laminin α1 chain is deficient in an organism, an embryo dies, likely as a result of a defective Reichert’s membrane due to a lack of laminin–111 being produced. Laminin-111 has been identified as a crucial molecule for development of the embryo as shown by the consequences that occur when laminin-111 is lacking.".
- Laminin_111 thumbnail Schematic_Diagram_of_Laminin_111.jpg?width=300.
- Laminin_111 wikiPageID "37656184".
- Laminin_111 wikiPageLength "12204".
- Laminin_111 wikiPageOutDegree "21".
- Laminin_111 wikiPageRevisionID "702874569".
- Laminin_111 wikiPageWikiLink Blastocyst.
- Laminin_111 wikiPageWikiLink Blood_vessel.
- Laminin_111 wikiPageWikiLink Category:Carbohydrate_chemistry.
- Laminin_111 wikiPageWikiLink Category:Glycoproteins.
- Laminin_111 wikiPageWikiLink Cytoskeleton.
- Laminin_111 wikiPageWikiLink Duchenne_muscular_dystrophy.
- Laminin_111 wikiPageWikiLink Dystroglycan.
- Laminin_111 wikiPageWikiLink Embryo.
- Laminin_111 wikiPageWikiLink Extracellular_matrix.
- Laminin_111 wikiPageWikiLink Kidney.
- Laminin_111 wikiPageWikiLink Laminin.
- Laminin_111 wikiPageWikiLink Lawrence_Berkeley_National_Laboratory.
- Laminin_111 wikiPageWikiLink Liver.
- Laminin_111 wikiPageWikiLink Neuromuscular_junction.
- Laminin_111 wikiPageWikiLink Nitric_oxide.
- Laminin_111 wikiPageWikiLink Ovary.
- Laminin_111 wikiPageWikiLink Sulfated_glycolipids.
- Laminin_111 wikiPageWikiLink Testicle.
- Laminin_111 wikiPageWikiLink United_States_Department_of_Energy.
- Laminin_111 wikiPageWikiLink File:Laminin_Basement_Layer.jpg.
- Laminin_111 wikiPageWikiLink File:Schematic_Diagram_of_Laminin_111.jpg.
- Laminin_111 wikiPageUsesTemplate Template:Lead_missing.
- Laminin_111 wikiPageUsesTemplate Template:Multiple_issues.
- Laminin_111 wikiPageUsesTemplate Template:Orphan.
- Laminin_111 wikiPageUsesTemplate Template:Reflist.
- Laminin_111 wikiPageUsesTemplate Template:Underlinked.
- Laminin_111 subject Category:Carbohydrate_chemistry.
- Laminin_111 subject Category:Glycoproteins.
- Laminin_111 type Page.
- Laminin_111 comment "One of the first laminin isoforms to be discovered (and named accordingly so) was laminin–1, more accurately denoted as laminin–111. The “111” identifies the isoform's chain composition of α1β1γ1. The distribution of the different laminin isoforms is tissue-specific. Laminin–111 is predominantly expressed in the embryonic epithelium, but can also be found in some adult epithelium such as the kidney, liver, testis, ovaries, and brain blood vessels.".
- Laminin_111 label "Laminin 111".
- Laminin_111 sameAs Q6482005.
- Laminin_111 sameAs m.0nhh0_2.
- Laminin_111 sameAs Q6482005.
- Laminin_111 wasDerivedFrom Laminin_111?oldid=702874569.
- Laminin_111 depiction Schematic_Diagram_of_Laminin_111.jpg.
- Laminin_111 isPrimaryTopicOf Laminin_111.