Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/LJ-001> ?p ?o }
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- LJ-001 abstract "LJ-001 is a broad-spectrum antiviral drug developed as a potential treatment for enveloped viruses. It acts as an inhibitor which blocks viral entry into host cells at a step after virus binding but before virus–cell fusion, and also irreversibly inactivates the virions themselves by generating reactive singlet oxygen molecules which damage the viral membrane. In cell culture tests in vitro, LJ-001 was able to block and disable a wide range of different viruses, including influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV. Unfortunately LJ-001 itself was unsuitable for further development, as it has poor physiological stability and requires light for its antiviral mechanism to operate. However the discovery of this novel mechanism for blocking virus entry and disabling the virion particles has led to LJ-001 being used as a lead compound to develop a novel family of more effective antiviral drugs with improved properties.".
- LJ-001 casNumber "851305-26-5".
- LJ-001 iupacName "(5Z)-5-[(5-phenylfuran-2-yl)methylidene]-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one".
- LJ-001 pubchem "2272467".
- LJ-001 thumbnail LJ-001_structure2.png?width=300.
- LJ-001 wikiPageID "44054592".
- LJ-001 wikiPageLength "5104".
- LJ-001 wikiPageOutDegree "18".
- LJ-001 wikiPageRevisionID "678516216".
- LJ-001 wikiPageWikiLink Antiviral_drug.
- LJ-001 wikiPageWikiLink Arenavirus.
- LJ-001 wikiPageWikiLink BCX4430.
- LJ-001 wikiPageWikiLink Brincidofovir.
- LJ-001 wikiPageWikiLink Bunyaviridae.
- LJ-001 wikiPageWikiLink Category:Antivirals.
- LJ-001 wikiPageWikiLink FGI-103.
- LJ-001 wikiPageWikiLink FGI-104.
- LJ-001 wikiPageWikiLink FGI-106.
- LJ-001 wikiPageWikiLink Favipiravir.
- LJ-001 wikiPageWikiLink Filoviridae.
- LJ-001 wikiPageWikiLink Flavivirus.
- LJ-001 wikiPageWikiLink HIV.
- LJ-001 wikiPageWikiLink Influenza_A_virus.
- LJ-001 wikiPageWikiLink Lead_compound.
- LJ-001 wikiPageWikiLink Paramyxoviridae.
- LJ-001 wikiPageWikiLink Poxviridae.
- LJ-001 wikiPageWikiLink Singlet_oxygen.
- LJ-001 wikiPageWikiLinkText "LJ-001".
- LJ-001 c "17".
- LJ-001 casNumber "851305".
- LJ-001 chemspiderid "23288467".
- LJ-001 h "13".
- LJ-001 inchi "1".
- LJ-001 inchikey "YAIFLEPRFXXIFQ-PTNGSMBKBW".
- LJ-001 iupacName "-5".
- LJ-001 molecularWeight "327.42".
- LJ-001 n "1".
- LJ-001 o "2".
- LJ-001 pubchem "2272467".
- LJ-001 s "2".
- LJ-001 smiles "c3ccccc3-coc2\C=C/SCN1CC=C".
- LJ-001 stdinchi "1".
- LJ-001 stdinchikey "YAIFLEPRFXXIFQ-PTNGSMBKSA-N".
- LJ-001 wikiPageUsesTemplate Template:Cascite.
- LJ-001 wikiPageUsesTemplate Template:Drugbankcite.
- LJ-001 wikiPageUsesTemplate Template:Drugbox.
- LJ-001 wikiPageUsesTemplate Template:Pharm-stub.
- LJ-001 wikiPageUsesTemplate Template:Reflist.
- LJ-001 subject Category:Antivirals.
- LJ-001 hypernym Drug.
- LJ-001 type ChemicalSubstance.
- LJ-001 type Drug.
- LJ-001 type ChemicalObject.
- LJ-001 type Thing.
- LJ-001 type Q8386.
- LJ-001 comment "LJ-001 is a broad-spectrum antiviral drug developed as a potential treatment for enveloped viruses. It acts as an inhibitor which blocks viral entry into host cells at a step after virus binding but before virus–cell fusion, and also irreversibly inactivates the virions themselves by generating reactive singlet oxygen molecules which damage the viral membrane.".
- LJ-001 label "LJ-001".
- LJ-001 sameAs Q18344440.
- LJ-001 sameAs LJ-001.
- LJ-001 sameAs LJ-001.
- LJ-001 sameAs m.0121_nxr.
- LJ-001 sameAs Q18344440.
- LJ-001 wasDerivedFrom LJ-001?oldid=678516216.
- LJ-001 depiction LJ-001_structure2.png.
- LJ-001 isPrimaryTopicOf LJ-001.