Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/LGMN> ?p ?o }
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- LGMN abstract "Legumain is a protein that in humans is encoded by the LGMN gene.This gene encodes a cysteine protease, legumain, that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform.".
- LGMN entrezgene "5641".
- LGMN wikiPageID "14875072".
- LGMN wikiPageLength "8006".
- LGMN wikiPageOutDegree "3".
- LGMN wikiPageRevisionID "673293183".
- LGMN wikiPageWikiLink Gene.
- LGMN wikiPageWikiLink Legumain.
- LGMN wikiPageWikiLink Protein.
- LGMN wikiPageWikiLinkText "LGMN".
- LGMN requireManualInspection "no".
- LGMN summaryText "This gene encodes a cysteine protease, legumain, that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform.".
- LGMN updateCitations "yes".
- LGMN updatePage "yes".
- LGMN updateProteinBox "yes".
- LGMN updateSummary "yes".
- LGMN wikiPageUsesTemplate Template:Cite_journal.
- LGMN wikiPageUsesTemplate Template:Gene-14-stub.
- LGMN wikiPageUsesTemplate Template:Multiple_issues.
- LGMN wikiPageUsesTemplate Template:Orphan.
- LGMN wikiPageUsesTemplate Template:PBB.
- LGMN wikiPageUsesTemplate Template:PBB_Controls.
- LGMN wikiPageUsesTemplate Template:PBB_Further_reading.
- LGMN wikiPageUsesTemplate Template:PBB_Summary.
- LGMN wikiPageUsesTemplate Template:Refbegin.
- LGMN wikiPageUsesTemplate Template:Refend.
- LGMN wikiPageUsesTemplate Template:Reflist.
- LGMN wikiPageUsesTemplate Template:Underlinked.
- LGMN hypernym Protein.
- LGMN type Biomolecule.
- LGMN type Protein.
- LGMN type Thing.
- LGMN type Q206229.
- LGMN type Q8054.
- LGMN comment "Legumain is a protein that in humans is encoded by the LGMN gene.This gene encodes a cysteine protease, legumain, that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells.".
- LGMN label "LGMN".
- LGMN sameAs Q18030821.
- LGMN sameAs m.03g_v9w.
- LGMN sameAs Q18030821.
- LGMN wasDerivedFrom LGMN?oldid=673293183.
- LGMN isPrimaryTopicOf LGMN.