Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/LF22-0542> ?p ?o }
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- LF22-0542 abstract "LF22-0542 is a non-peptide bradykinin B1 antagonist. It displayed binding Ki values of 0.35 and 6.5 nM at cloned human and mouse B1 receptors, respectively, while having no affinity for either human, mouse, or rat B2 receptors at concentrations up to 10 μM. This means that LF22-0542 is at least 4000 times selective for the B1 receptor over the B2 receptor. Systemic administration of LF22-0542 inhibited acute pain induced by acetic acid, formalin, and a hot plate. It also reversed acute inflammatory pain induced by carrageenan, and persistent inflammatory pain induced by CFA. In a neuropathic pain model, LF22-0542 reversed the thermal hyperalgesia, but not the mechanical hyperalgesia.".
- LF22-0542 iupacName "N-4-(4,5-Dihydro-1H-imidazol-2-yl)phenyl]methyl]-2-[2-[[(4-methoxy-2,6-dimethylphenyl) sulfonyl]methylamino]ethoxy]-N-methylacetamide".
- LF22-0542 thumbnail LF_22-0542.svg?width=300.
- LF22-0542 wikiPageID "34101006".
- LF22-0542 wikiPageLength "2234".
- LF22-0542 wikiPageOutDegree "14".
- LF22-0542 wikiPageRevisionID "670417222".
- LF22-0542 wikiPageWikiLink Acetic_acid.
- LF22-0542 wikiPageWikiLink Antagonist.
- LF22-0542 wikiPageWikiLink Bradykinin_receptor_B1.
- LF22-0542 wikiPageWikiLink Bradykinin_receptor_B2.
- LF22-0542 wikiPageWikiLink Carrageenan.
- LF22-0542 wikiPageWikiLink Category:Analgesics.
- LF22-0542 wikiPageWikiLink Category:Anti-inflammatory_agents.
- LF22-0542 wikiPageWikiLink Category:Imidazolines.
- LF22-0542 wikiPageWikiLink Category:Sulfonamides.
- LF22-0542 wikiPageWikiLink Formaldehyde.
- LF22-0542 wikiPageWikiLink Freunds_adjuvant.
- LF22-0542 wikiPageWikiLink Hyperalgesia.
- LF22-0542 wikiPageWikiLink Neuropathic_pain.
- LF22-0542 wikiPageWikiLink nowiki%3E(4-methoxy-2,6-dimethylphenyl)_sulfonyl%5Dmethylamino%5Dethoxy%5D-N-methylacetamide.
- LF22-0542 wikiPageWikiLinkText "LF22-0542".
- LF22-0542 imagefile "LF 22-0542.svg".
- LF22-0542 imagesize "200".
- LF22-0542 iupacname "N-4-(4,5-Dihydro-1H-imidazol-2-yl)phenyl]methyl]-2-[2-[[(4-methoxy-2,6-dimethylphenyl) sulfonyl]methylamino]ethoxy]-N-methylacetamide".
- LF22-0542 wikiPageUsesTemplate Template:Cascite.
- LF22-0542 wikiPageUsesTemplate Template:Chembox.
- LF22-0542 wikiPageUsesTemplate Template:Chembox_Hazards.
- LF22-0542 wikiPageUsesTemplate Template:Chembox_Identifiers.
- LF22-0542 wikiPageUsesTemplate Template:Chembox_Properties.
- LF22-0542 wikiPageUsesTemplate Template:Peptidergics.
- LF22-0542 wikiPageUsesTemplate Template:Reflist.
- LF22-0542 subject Category:Analgesics.
- LF22-0542 subject Category:Anti-inflammatory_agents.
- LF22-0542 subject Category:Imidazolines.
- LF22-0542 subject Category:Sulfonamides.
- LF22-0542 hypernym Antagonist.
- LF22-0542 type Agent.
- LF22-0542 type ChemicalCompound.
- LF22-0542 type ChemicalSubstance.
- LF22-0542 type Drug.
- LF22-0542 type Agent.
- LF22-0542 type Amide.
- LF22-0542 type Analgesic.
- LF22-0542 type Chemical.
- LF22-0542 type Drug.
- LF22-0542 type Heterocycle.
- LF22-0542 type Sulfonamide.
- LF22-0542 type ChemicalObject.
- LF22-0542 type Thing.
- LF22-0542 type Q11173.
- LF22-0542 comment "LF22-0542 is a non-peptide bradykinin B1 antagonist. It displayed binding Ki values of 0.35 and 6.5 nM at cloned human and mouse B1 receptors, respectively, while having no affinity for either human, mouse, or rat B2 receptors at concentrations up to 10 μM. This means that LF22-0542 is at least 4000 times selective for the B1 receptor over the B2 receptor. Systemic administration of LF22-0542 inhibited acute pain induced by acetic acid, formalin, and a hot plate.".
- LF22-0542 label "LF22-0542".
- LF22-0542 sameAs Q6457712.
- LF22-0542 sameAs m.0hr0294.
- LF22-0542 sameAs LF22-0542.
- LF22-0542 sameAs LF22-0542.
- LF22-0542 sameAs Q6457712.
- LF22-0542 wasDerivedFrom LF22-0542?oldid=670417222.
- LF22-0542 depiction LF_22-0542.svg.
- LF22-0542 isPrimaryTopicOf LF22-0542.