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- Karyopherin_alpha_2 abstract "Importin subunit alpha-2 is a protein that in humans is encoded by the KPNA2 gene.The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import are members of the alpha importin family of karyopherins such as importin subunit alpha-2. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination".
- Karyopherin_alpha_2 entrezgene "3838".
- Karyopherin_alpha_2 wikiPageID "14058681".
- Karyopherin_alpha_2 wikiPageLength "12656".
- Karyopherin_alpha_2 wikiPageOutDegree "26".
- Karyopherin_alpha_2 wikiPageRevisionID "696369400".
- Karyopherin_alpha_2 wikiPageWikiLink ARL4A.
- Karyopherin_alpha_2 wikiPageWikiLink African_clawed_frog.
- Karyopherin_alpha_2 wikiPageWikiLink Category:Basic_amino_acids.
- Karyopherin_alpha_2 wikiPageWikiLink Cell_nucleus.
- Karyopherin_alpha_2 wikiPageWikiLink Gene.
- Karyopherin_alpha_2 wikiPageWikiLink ITK_(gene).
- Karyopherin_alpha_2 wikiPageWikiLink Importin.
- Karyopherin_alpha_2 wikiPageWikiLink KPNB1.
- Karyopherin_alpha_2 wikiPageWikiLink Karyopherin.
- Karyopherin_alpha_2 wikiPageWikiLink Non-covalent_interactions.
- Karyopherin_alpha_2 wikiPageWikiLink Nuclear_localization_sequence.
- Karyopherin_alpha_2 wikiPageWikiLink Nuclear_membrane.
- Karyopherin_alpha_2 wikiPageWikiLink Nuclear_pore.
- Karyopherin_alpha_2 wikiPageWikiLink PLAG1.
- Karyopherin_alpha_2 wikiPageWikiLink Permissive_temperature.
- Karyopherin_alpha_2 wikiPageWikiLink Protein.
- Karyopherin_alpha_2 wikiPageWikiLink Protein–protein_interaction.
- Karyopherin_alpha_2 wikiPageWikiLink RECQL.
- Karyopherin_alpha_2 wikiPageWikiLink RNA_polymerase_I.
- Karyopherin_alpha_2 wikiPageWikiLink Ran_(gene).
- Karyopherin_alpha_2 wikiPageWikiLink SGK.
- Karyopherin_alpha_2 wikiPageWikiLink SV40_large_T_antigen.
- Karyopherin_alpha_2 wikiPageWikiLink Saccharomyces_cerevisiae.
- Karyopherin_alpha_2 wikiPageWikiLink V(D)J_recombination.
- Karyopherin_alpha_2 wikiPageWikiLinkText "KPNA2".
- Karyopherin_alpha_2 wikiPageWikiLinkText "Karyopherin alpha 2".
- Karyopherin_alpha_2 wikiPageWikiLinkText "importin".
- Karyopherin_alpha_2 wikiPageWikiLinkText "importin-α2".
- Karyopherin_alpha_2 wikiPageUsesTemplate Template:Cite_journal.
- Karyopherin_alpha_2 wikiPageUsesTemplate Template:Div_col.
- Karyopherin_alpha_2 wikiPageUsesTemplate Template:Div_col_end.
- Karyopherin_alpha_2 wikiPageUsesTemplate Template:PBB.
- Karyopherin_alpha_2 wikiPageUsesTemplate Template:PDB_Gallery.
- Karyopherin_alpha_2 wikiPageUsesTemplate Template:Refbegin.
- Karyopherin_alpha_2 wikiPageUsesTemplate Template:Refend.
- Karyopherin_alpha_2 wikiPageUsesTemplate Template:Reflist.
- Karyopherin_alpha_2 hypernym Protein.
- Karyopherin_alpha_2 type Biomolecule.
- Karyopherin_alpha_2 type Protein.
- Karyopherin_alpha_2 type Thing.
- Karyopherin_alpha_2 type Q206229.
- Karyopherin_alpha_2 type Q8054.
- Karyopherin_alpha_2 comment "Importin subunit alpha-2 is a protein that in humans is encoded by the KPNA2 gene.The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex.".
- Karyopherin_alpha_2 label "Karyopherin alpha 2".
- Karyopherin_alpha_2 sameAs Q18028346.
- Karyopherin_alpha_2 sameAs m.03cs9rm.
- Karyopherin_alpha_2 sameAs Q18028346.
- Karyopherin_alpha_2 wasDerivedFrom Karyopherin_alpha_2?oldid=696369400.
- Karyopherin_alpha_2 isPrimaryTopicOf Karyopherin_alpha_2.