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- JWH-133 abstract "JWH-133 is a potent selective CB2 receptor agonist with a Ki of 3.4nM and selectivity of around 200x for CB2 over CB1 receptors. It was discovered by and named after, John W. Huffman.JWH-133, alongside WIN 55,212-2 and HU-210, is responsible for preventing the inflammation caused by Amyloid beta proteins involved in Alzheimer's Disease, in addition to preventing cognitive impairment and loss of neuronal markers. This anti-inflammatory action is induced through agonist action at cannabinoid receptors, which prevents microglial activation that elicits the inflammation. Additionally, cannabinoids completely abolish neurotoxicity related to microglia activation in rat models.It may be linked with anti-cancer properties, according to pre-trial data from a 2010 study in Madrid.".
- JWH-133 casNumber "259869-55-1".
- JWH-133 iupacName "(6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro -6,6,9-trimethyl-6H-dibenzo[b,d]pyran".
- JWH-133 pubchem "6918505".
- JWH-133 thumbnail JWH-133.png?width=300.
- JWH-133 wikiPageID "6286309".
- JWH-133 wikiPageLength "3886".
- JWH-133 wikiPageOutDegree "11".
- JWH-133 wikiPageRevisionID "684383672".
- JWH-133 wikiPageWikiLink Alzheimers_disease.
- JWH-133 wikiPageWikiLink Amyloid_beta.
- JWH-133 wikiPageWikiLink Cannabinoid_receptor.
- JWH-133 wikiPageWikiLink Cannabinoid_receptor_type_1.
- JWH-133 wikiPageWikiLink Cannabinoid_receptor_type_2.
- JWH-133 wikiPageWikiLink Dissociation_constant.
- JWH-133 wikiPageWikiLink HU-210.
- JWH-133 wikiPageWikiLink JWH-018.
- JWH-133 wikiPageWikiLink John_W._Huffman.
- JWH-133 wikiPageWikiLink Microglia.
- JWH-133 wikiPageWikiLink WIN_55,212-2.
- JWH-133 wikiPageWikiLinkText "JWH-133".
- JWH-133 c "22".
- JWH-133 casNumber "259869".
- JWH-133 chembl "371214".
- JWH-133 chemspiderid "5293702".
- JWH-133 h "32".
- JWH-133 inchi "1".
- JWH-133 inchikey "YSBFLLZNALVODA-RBUKOAKNBY".
- JWH-133 iupacName "-3".
- JWH-133 iupharLigand "747".
- JWH-133 molecularWeight "312.489".
- JWH-133 o "1".
- JWH-133 pubchem "6918505".
- JWH-133 smiles "O3c1ccCCCC".
- JWH-133 stdinchi "1".
- JWH-133 stdinchikey "YSBFLLZNALVODA-RBUKOAKNSA-N".
- JWH-133 verifiedfields "changed".
- JWH-133 verifiedrevid "477496056".
- JWH-133 width "200".
- JWH-133 wikiPageUsesTemplate Template:Cascite.
- JWH-133 wikiPageUsesTemplate Template:Chemspidercite.
- JWH-133 wikiPageUsesTemplate Template:Citation_needed.
- JWH-133 wikiPageUsesTemplate Template:Drugbox.
- JWH-133 wikiPageUsesTemplate Template:Ebicite.
- JWH-133 wikiPageUsesTemplate Template:Stdinchicite.
- JWH-133 hypernym Agonist.
- JWH-133 type ChemicalSubstance.
- JWH-133 type Drug.
- JWH-133 type Cannabinoid.
- JWH-133 type Chemical.
- JWH-133 type Drug.
- JWH-133 type Heterocycle.
- JWH-133 type ChemicalObject.
- JWH-133 type Thing.
- JWH-133 type Q8386.
- JWH-133 comment "JWH-133 is a potent selective CB2 receptor agonist with a Ki of 3.4nM and selectivity of around 200x for CB2 over CB1 receptors. It was discovered by and named after, John W. Huffman.JWH-133, alongside WIN 55,212-2 and HU-210, is responsible for preventing the inflammation caused by Amyloid beta proteins involved in Alzheimer's Disease, in addition to preventing cognitive impairment and loss of neuronal markers.".
- JWH-133 label "JWH-133".
- JWH-133 sameAs Q6109195.
- JWH-133 sameAs m.0f_j08.
- JWH-133 sameAs JWH-133.
- JWH-133 sameAs JWH-133.
- JWH-133 sameAs Q6109195.
- JWH-133 wasDerivedFrom JWH-133?oldid=684383672.
- JWH-133 depiction JWH-133.png.
- JWH-133 isPrimaryTopicOf JWH-133.