Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/JARID2> ?p ?o }
Showing triples 1 to 73 of
73
with 100 triples per page.
- JARID2 abstract "Protein Jumonji is a protein that in humans is encoded by the JARID2 gene.Jarid2 (jumonji, AT rich interactive domain 2) is a protein coding gene that functions as a putative transcription factor. Distinguished as a nuclear protein necessary for mouse embryogenesis, Jarid2 is a member of the jumonji family that contains a DNA binding domain known as the AT-rich interaction domain (ARID)[2, 8, 11, 13]. In vitro studies of Jarid2 reveal that ARID along with other functional domains are involved in DNA binding, nuclear localization, transcriptional repression [5], and recruitment of Polycomb-repressive complex 2 (PRC2) [9, 10]. Intracellular mechanisms underlying these interactions remain largely unknown.In search of developmentally important genes, Jarid2 has previously been identified by gene trap technology as an important factor necessary for organ development [2, 3, 5]. During mouse organogenesis, Jarid2 is involved in the formation of the neural tube and development of the liver, spleen, thymus and cardiovascular system [6, 12]. Continuous Jarid2 expression in the tissues of the heart, highlight its presiding role in the development of both the embryonic and the adult heart [2]. Mutant models of Jarid2 embryos show severe heart malformations, ventricular septal defects, noncompaction of the ventricular wall, and dilated atria [4]. Homozygous mutants of Jarid2 are found to die soon after birth [4]. Overexpression of the mouse Jarid2 gene has been reported to repress cardiomyocyte proliferation through it close interaction with retinoblastoma protein (Rb), a master cell cycle regulator [3, 5, 7]. Retinoblastoma-binding protein-2 and the human SMCX protein share regions of homology between mice and humans [1, 14].".
- JARID2 entrezgene "3720".
- JARID2 wikiPageID "15215486".
- JARID2 wikiPageLength "13594".
- JARID2 wikiPageOutDegree "36".
- JARID2 wikiPageRevisionID "702213948".
- JARID2 wikiPageWikiLink Antibody.
- JARID2 wikiPageWikiLink Auditory_brainstem_response.
- JARID2 wikiPageWikiLink Blood_plasma.
- JARID2 wikiPageWikiLink Category:EC_1.14.11.
- JARID2 wikiPageWikiLink Category:Genes_mutated_in_mice.
- JARID2 wikiPageWikiLink Category:Human_2OG_oxygenases.
- JARID2 wikiPageWikiLink Category:Transcription_factors.
- JARID2 wikiPageWikiLink Citrobacter.
- JARID2 wikiPageWikiLink Clinical_chemistry.
- JARID2 wikiPageWikiLink Dominance_(genetics).
- JARID2 wikiPageWikiLink Dual-energy_X-ray_absorptiometry.
- JARID2 wikiPageWikiLink Edema.
- JARID2 wikiPageWikiLink Gene.
- JARID2 wikiPageWikiLink Glucose_tolerance_test.
- JARID2 wikiPageWikiLink Hematology.
- JARID2 wikiPageWikiLink Hot_plate_test.
- JARID2 wikiPageWikiLink Indirect_calorimetry.
- JARID2 wikiPageWikiLink International_Knockout_Mouse_Consortium.
- JARID2 wikiPageWikiLink Knockout_mouse.
- JARID2 wikiPageWikiLink Mendelian_inheritance.
- JARID2 wikiPageWikiLink Micronucleus_test.
- JARID2 wikiPageWikiLink Model_organism.
- JARID2 wikiPageWikiLink Mutant.
- JARID2 wikiPageWikiLink Open_Field_(animal_test).
- JARID2 wikiPageWikiLink Peripheral_blood_lymphocyte.
- JARID2 wikiPageWikiLink Phenotype.
- JARID2 wikiPageWikiLink Phenotypic_screening.
- JARID2 wikiPageWikiLink Protein.
- JARID2 wikiPageWikiLink Radiography.
- JARID2 wikiPageWikiLink Salmonella.
- JARID2 wikiPageWikiLink Teratology.
- JARID2 wikiPageWikiLink Weaning.
- JARID2 wikiPageWikiLink Wellcome_Trust_Sanger_Institute.
- JARID2 wikiPageWikiLink Zygosity.
- JARID2 wikiPageWikiLinkText "JARID2".
- JARID2 wikiPageUsesTemplate Template:Cite_journal.
- JARID2 wikiPageUsesTemplate Template:Dioxygenases.
- JARID2 wikiPageUsesTemplate Template:Enzymes.
- JARID2 wikiPageUsesTemplate Template:MeshName.
- JARID2 wikiPageUsesTemplate Template:NLM_content.
- JARID2 wikiPageUsesTemplate Template:PBB.
- JARID2 wikiPageUsesTemplate Template:Portal_bar.
- JARID2 wikiPageUsesTemplate Template:Refbegin.
- JARID2 wikiPageUsesTemplate Template:Refend.
- JARID2 wikiPageUsesTemplate Template:Reflist.
- JARID2 wikiPageUsesTemplate Template:Transcription_factors.
- JARID2 subject Category:EC_1.14.11.
- JARID2 subject Category:Genes_mutated_in_mice.
- JARID2 subject Category:Human_2OG_oxygenases.
- JARID2 subject Category:Transcription_factors.
- JARID2 hypernym Protein.
- JARID2 type Biomolecule.
- JARID2 type Protein.
- JARID2 type Factor.
- JARID2 type Institute.
- JARID2 type Redirect.
- JARID2 type Source.
- JARID2 type Thing.
- JARID2 type Q206229.
- JARID2 type Q8054.
- JARID2 comment "Protein Jumonji is a protein that in humans is encoded by the JARID2 gene.Jarid2 (jumonji, AT rich interactive domain 2) is a protein coding gene that functions as a putative transcription factor. Distinguished as a nuclear protein necessary for mouse embryogenesis, Jarid2 is a member of the jumonji family that contains a DNA binding domain known as the AT-rich interaction domain (ARID)[2, 8, 11, 13].".
- JARID2 label "JARID2".
- JARID2 sameAs Q18028093.
- JARID2 sameAs m.03hm44_.
- JARID2 sameAs Q18028093.
- JARID2 wasDerivedFrom JARID2?oldid=702213948.
- JARID2 isPrimaryTopicOf JARID2.