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- Induced_coma abstract "A barbiturate-induced coma, or barb coma, is a temporary coma (a deep state of unconsciousness) brought on by a controlled dose of a barbiturate drug, usually pentobarbital or thiopental. Barbiturate comas are used to protect the brain during major neurosurgery, and as a last line of treatment in certain cases of status epilepticus that have not responded to other treatments. Because patients are often seriously ill or injured, and are under general anesthesia and in a coma, careful airway management, which involves some form of mechanical ventilation, is needed.Barbiturates reduce the metabolic rate of brain tissue, as well as the cerebral blood flow. With these reductions, the blood vessels in the brain narrow, decreasing the amount of space occupied by the brain, and hence the intracranial pressure. The hope is that, with the swelling relieved, the pressure decreases and some or all brain damage may be averted. Several studies have supported this theory by showing reduced mortality when treating refractory intracranial hypertension with a barbiturate coma.Controversy exists, however, over the benefits of using barbiturates to control intracranial hypertension. Some studies have shown that barbiturate-induced coma can reduce intracranial hypertension but does not necessarily prevent brain damage. Furthermore, the reduction in intracranial hypertension may not be sustained. Some randomized trials have failed to demonstrate any survival or morbidity benefit of induced coma in diverse conditions such as neurosurgical operations, head trauma, intracranial aneurysm rupture, intracranial hemorrhage, ischemic stroke, and status epilepticus. If the patient survives, cognitive impairment may also follow recovery from the coma.About 55% of the glucose and oxygen use by the brain is meant for its electrical activity and the rest for all other activities such as metabolism. This is recognized by a device such as an electroencephalogram (EEG), which measures electrical activity in the brain. When barbiturates are given to brain injured patients for induced coma, they act by reducing the electrical activity of the brain, which in theory reduces the metabolic and oxygen demand. Once there is improvement in the patient's general condition, the barbiturates are withdrawn gradually and the patient regains consciousness.Induced coma is used in the treatment of symptomatic rabies through the Milwaukee protocol, first attempted in 2004.".
- Induced_coma wikiPageID "1275750".
- Induced_coma wikiPageLength "5023".
- Induced_coma wikiPageOutDegree "27".
- Induced_coma wikiPageRevisionID "691001086".
- Induced_coma wikiPageWikiLink Barbiturate.
- Induced_coma wikiPageWikiLink Blood_vessel.
- Induced_coma wikiPageWikiLink Brain.
- Induced_coma wikiPageWikiLink Brain_damage.
- Induced_coma wikiPageWikiLink Category:Coma.
- Induced_coma wikiPageWikiLink Category:Intensive_care_medicine.
- Induced_coma wikiPageWikiLink Category:Neurology_procedures.
- Induced_coma wikiPageWikiLink Cerebral_blood_flow.
- Induced_coma wikiPageWikiLink Coma.
- Induced_coma wikiPageWikiLink Electroencephalography.
- Induced_coma wikiPageWikiLink Head_injury.
- Induced_coma wikiPageWikiLink Insulin_shock_therapy.
- Induced_coma wikiPageWikiLink Intracranial_aneurysm.
- Induced_coma wikiPageWikiLink Intracranial_hemorrhage.
- Induced_coma wikiPageWikiLink Intracranial_pressure.
- Induced_coma wikiPageWikiLink Milwaukee_protocol.
- Induced_coma wikiPageWikiLink Neurosurgery.
- Induced_coma wikiPageWikiLink Pentobarbital.
- Induced_coma wikiPageWikiLink Rabies.
- Induced_coma wikiPageWikiLink Randomized_controlled_trial.
- Induced_coma wikiPageWikiLink Sodium_thiopental.
- Induced_coma wikiPageWikiLink Status_epilepticus.
- Induced_coma wikiPageWikiLink Stroke.
- Induced_coma wikiPageWikiLink Traumatic_brain_injury.
- Induced_coma wikiPageWikiLink Unconsciousness.
- Induced_coma wikiPageWikiLinkText "Induced coma".
- Induced_coma wikiPageWikiLinkText "Medically induced comas".
- Induced_coma wikiPageWikiLinkText "artificial coma".
- Induced_coma wikiPageWikiLinkText "artificially induced coma".
- Induced_coma wikiPageWikiLinkText "chemical coma".
- Induced_coma wikiPageWikiLinkText "chemically induced coma".
- Induced_coma wikiPageWikiLinkText "coma".
- Induced_coma wikiPageWikiLinkText "drug that will paralyze him".
- Induced_coma wikiPageWikiLinkText "induced coma".
- Induced_coma wikiPageWikiLinkText "induced into a coma".
- Induced_coma wikiPageWikiLinkText "induced".
- Induced_coma wikiPageWikiLinkText "medical coma".
- Induced_coma wikiPageWikiLinkText "medical comas".
- Induced_coma wikiPageWikiLinkText "medically induced coma".
- Induced_coma wikiPageWikiLinkText "medically induced comas".
- Induced_coma wikiPageWikiLinkText "medically-induced coma".
- Induced_coma wikiPageUsesTemplate Template:Citation_needed.
- Induced_coma wikiPageUsesTemplate Template:Reflist.
- Induced_coma subject Category:Coma.
- Induced_coma subject Category:Intensive_care_medicine.
- Induced_coma subject Category:Neurology_procedures.
- Induced_coma hypernym Coma.
- Induced_coma type Album.
- Induced_coma type Redirect.
- Induced_coma type Specialty.
- Induced_coma comment "A barbiturate-induced coma, or barb coma, is a temporary coma (a deep state of unconsciousness) brought on by a controlled dose of a barbiturate drug, usually pentobarbital or thiopental. Barbiturate comas are used to protect the brain during major neurosurgery, and as a last line of treatment in certain cases of status epilepticus that have not responded to other treatments.".
- Induced_coma label "Induced coma".
- Induced_coma sameAs Q933408.
- Induced_coma sameAs Coma_inducido.
- Induced_coma sameAs Coma_farmacologico.
- Induced_coma sameAs Mākslīgā_koma.
- Induced_coma sameAs Śpiączka_farmakologiczna.
- Induced_coma sameAs Coma_induzido.
- Induced_coma sameAs m.04pc6z.
- Induced_coma sameAs Искусственная_кома.
- Induced_coma sameAs Q933408.
- Induced_coma wasDerivedFrom Induced_coma?oldid=691001086.
- Induced_coma isPrimaryTopicOf Induced_coma.