Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Idiotopes> ?p ?o }
Showing triples 1 to 33 of
33
with 100 triples per page.
- Idiotopes abstract "An idiotope is the unique set of antigenic determinants (epitopes) of the variable portion of an antibody. In some cases it can be the actual antigen-binding site, and in some cases it may comprise variable region sequences outside of the antigen-binding site on the antibody itself. Thus each antibody would have multiple idiotopes; and the set of these individual idiotopes is termed the idiotype of the antibody. Idiotopes contrast with allotopes, which are non-varying structures on the Fc receptor.If a separate antibody is produced that has specific binding capabilities to an idiotope of the previously described antibody, it is said to be an \"anti-idiotypic antibody\". If such is the case, the anti-idiotypic antibodies will be able to bind to the B lymphocyte receptor for the original antigen and inhibit the immune response to that antigen. This type of regulation was proposed by Niels Jerne in 1974. He termed it the \"Network Hypothesis\". This type of B lymphocyte regulation may be partially responsible for preventing an immune response from getting out of control, which would elicit damage to host tissue or even cause an autoimmune diseased state.Because of the resemblance of anti-idiotypic antibodies to the original antigen, vaccine studies have been performed. These types of vaccines are called \"idiotypic vaccines\". None are produced commercially to date.".
- Idiotopes wikiPageID "4295385".
- Idiotopes wikiPageLength "2087".
- Idiotopes wikiPageOutDegree "12".
- Idiotopes wikiPageRevisionID "383098379".
- Idiotopes wikiPageWikiLink Allotope.
- Idiotopes wikiPageWikiLink Antibody.
- Idiotopes wikiPageWikiLink Autoimmune_disease.
- Idiotopes wikiPageWikiLink B_cell.
- Idiotopes wikiPageWikiLink Category:Antibodies.
- Idiotopes wikiPageWikiLink Category:Immune_system.
- Idiotopes wikiPageWikiLink Epitope.
- Idiotopes wikiPageWikiLink Fc_receptor.
- Idiotopes wikiPageWikiLink Immune_system.
- Idiotopes wikiPageWikiLink Niels_Kaj_Jerne.
- Idiotopes wikiPageWikiLink Tissue_(biology).
- Idiotopes wikiPageWikiLink Vaccine.
- Idiotopes wikiPageWikiLinkText "Idiotopes".
- Idiotopes wikiPageWikiLinkText "idiotopes".
- Idiotopes wikiPageUsesTemplate Template:Biology-stub.
- Idiotopes wikiPageUsesTemplate Template:Reflist.
- Idiotopes subject Category:Antibodies.
- Idiotopes subject Category:Immune_system.
- Idiotopes hypernym Set.
- Idiotopes type Glycoprotein.
- Idiotopes comment "An idiotope is the unique set of antigenic determinants (epitopes) of the variable portion of an antibody. In some cases it can be the actual antigen-binding site, and in some cases it may comprise variable region sequences outside of the antigen-binding site on the antibody itself. Thus each antibody would have multiple idiotopes; and the set of these individual idiotopes is termed the idiotype of the antibody.".
- Idiotopes label "Idiotopes".
- Idiotopes sameAs Q5989022.
- Idiotopes sameAs Idiotop.
- Idiotopes sameAs m.0bvncq.
- Idiotopes sameAs Q5989022.
- Idiotopes wasDerivedFrom Idiotopes?oldid=383098379.
- Idiotopes isPrimaryTopicOf Idiotopes.