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- Iain_Cheeseman abstract "Iain Cheeseman investigates the role of the kinetochore, a group of proteins required for cell division and chromosome segregation. This core network of proteins facilitates the attachment of chromosomes to microtubule polymers—the spindle structures that attach to the ends of cells, pulling and dividing them during cell division. The kinetochore is critical to ensuring duplication without loss or damage to the genetic material. Cheeseman is also investigating the activities of the individual molecular machines that make up this structure and how these proteins are controlled and regulated.Cheeseman is noted for discovering multiple new kinetochore proteins within yeast, the Caenorhabditis elegans worm and human cells. He has focused particularly on the proteins that are required to generate connections with spindle microtubules. He recently demonstrated a critical and direct role for a protein complex called Ndc80 (coded for by the gene NDC80) in directly associating with microtubules.Because many cancers may be driven by errors in chromosome segregation, it is hoped that Cheeseman’s studies will provide payoffs in cancer research. Certain cancer drugs target the connection between chromosomes and spindle microtubules, and some of the major proteins in the kinetochore complex have been implicated in leukemia and other diseases.Cheeseman is currently a junior Faculty Member at Whitehead Institute and an Assistant Professor at MIT. He did his undergraduate training at Duke University, and his graduate work at the University of California, Berkeley, where he earned a doctorate in 2002. Cheeseman carried out his postdoctoral work in the lab of Arshad Desai at the Ludwig Institute for Cancer Research in San Diego and the University of California, San Diego.".
- Iain_Cheeseman almaMater Duke_University.
- Iain_Cheeseman award Fred_Hutchinson_Cancer_Research_Center.
- Iain_Cheeseman citizenship United_States.
- Iain_Cheeseman field Biochemistry.
- Iain_Cheeseman knownFor Kinetochore.
- Iain_Cheeseman residence United_States.
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- Iain_Cheeseman wikiPageWikiLink Biochemistry.
- Iain_Cheeseman wikiPageWikiLink Caenorhabditis_elegans.
- Iain_Cheeseman wikiPageWikiLink Cambridge,_Massachusetts.
- Iain_Cheeseman wikiPageWikiLink Category:Cell_biologists.
- Iain_Cheeseman wikiPageWikiLink Category:Duke_University_alumni.
- Iain_Cheeseman wikiPageWikiLink Category:Living_people.
- Iain_Cheeseman wikiPageWikiLink Category:University_of_California,_Berkeley_alumni.
- Iain_Cheeseman wikiPageWikiLink Category:Whitehead_Institute_faculty.
- Iain_Cheeseman wikiPageWikiLink Cell_division.
- Iain_Cheeseman wikiPageWikiLink Chromosome.
- Iain_Cheeseman wikiPageWikiLink Chromosome_segregation.
- Iain_Cheeseman wikiPageWikiLink Duke_University.
- Iain_Cheeseman wikiPageWikiLink Fred_Hutchinson_Cancer_Research_Center.
- Iain_Cheeseman wikiPageWikiLink Kinetochore.
- Iain_Cheeseman wikiPageWikiLink Leukemia.
- Iain_Cheeseman wikiPageWikiLink Ludwig_Cancer_Research.
- Iain_Cheeseman wikiPageWikiLink Massachusetts_Institute_of_Technology.
- Iain_Cheeseman wikiPageWikiLink Microtubule.
- Iain_Cheeseman wikiPageWikiLink NDC80.
- Iain_Cheeseman wikiPageWikiLink Protein.
- Iain_Cheeseman wikiPageWikiLink Spindle_apparatus.
- Iain_Cheeseman wikiPageWikiLink United_States.
- Iain_Cheeseman wikiPageWikiLink University_of_California,_Berkeley.
- Iain_Cheeseman wikiPageWikiLink University_of_California,_San_Diego.
- Iain_Cheeseman wikiPageWikiLink Whitehead_Institute.
- Iain_Cheeseman wikiPageWikiLink Yeast.
- Iain_Cheeseman wikiPageWikiLinkText "Iain Cheeseman".
- Iain_Cheeseman almaMater Duke_University.
- Iain_Cheeseman awards "Fellow, Jane Coffin Childs Memorial Fund for Medical Research".
- Iain_Cheeseman awards "Harold W. Weintraub Graduate Student Award, Fred Hutchinson Cancer Research Center".
- Iain_Cheeseman awards "Kerr Award for Research Excellence, Ludwig Institute".
- Iain_Cheeseman awards "Smith Family New Investigator Award".
- Iain_Cheeseman citizenship United_States.
- Iain_Cheeseman fields Biochemistry.
- Iain_Cheeseman knownFor Kinetochore.
- Iain_Cheeseman name "Cheeseman, Iain".
- Iain_Cheeseman name "Iain Cheeseman".
- Iain_Cheeseman residence United_States.
- Iain_Cheeseman shortDescription "American biologist".
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- Iain_Cheeseman workplaces Ludwig_Cancer_Research.
- Iain_Cheeseman workplaces Massachusetts_Institute_of_Technology.
- Iain_Cheeseman workplaces University_of_California,_San_Diego.
- Iain_Cheeseman workplaces "Whitehead Institute for Biomedical Research".
- Iain_Cheeseman description "American biologist".
- Iain_Cheeseman description "American biologist".
- Iain_Cheeseman subject Category:Cell_biologists.
- Iain_Cheeseman subject Category:Duke_University_alumni.
- Iain_Cheeseman subject Category:Living_people.
- Iain_Cheeseman subject Category:University_of_California,_Berkeley_alumni.
- Iain_Cheeseman subject Category:Whitehead_Institute_faculty.
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- Iain_Cheeseman comment "Iain Cheeseman investigates the role of the kinetochore, a group of proteins required for cell division and chromosome segregation. This core network of proteins facilitates the attachment of chromosomes to microtubule polymers—the spindle structures that attach to the ends of cells, pulling and dividing them during cell division. The kinetochore is critical to ensuring duplication without loss or damage to the genetic material.".
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- Iain_Cheeseman givenName "Iain".
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- Iain_Cheeseman name "Cheeseman, Iain".
- Iain_Cheeseman name "Iain Cheeseman".
- Iain_Cheeseman surname "Cheeseman".