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- IDH3A abstract "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3α) is an enzyme that in humans is encoded by the IDH3A gene.Isocitrate dehydrogenases (IDHs) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008]".
- IDH3A entrezgene "3419".
- IDH3A wikiPageID "14874326".
- IDH3A wikiPageLength "14451".
- IDH3A wikiPageOutDegree "56".
- IDH3A wikiPageRevisionID "702233801".
- IDH3A wikiPageWikiLink Adenosine_triphosphate.
- IDH3A wikiPageWikiLink Allosteric_regulation.
- IDH3A wikiPageWikiLink Alpha-Ketoglutaric_acid.
- IDH3A wikiPageWikiLink Amino_acid.
- IDH3A wikiPageWikiLink Angiogenesis.
- IDH3A wikiPageWikiLink Arginine.
- IDH3A wikiPageWikiLink Aspartic_acid.
- IDH3A wikiPageWikiLink Bipolar_disorder.
- IDH3A wikiPageWikiLink Cancer.
- IDH3A wikiPageWikiLink Carboxylation.
- IDH3A wikiPageWikiLink Catalysis.
- IDH3A wikiPageWikiLink Category:EC_2.7.11.
- IDH3A wikiPageWikiLink Cerebellum.
- IDH3A wikiPageWikiLink Citric_acid_cycle.
- IDH3A wikiPageWikiLink Cytosol.
- IDH3A wikiPageWikiLink Electron_acceptor.
- IDH3A wikiPageWikiLink Electron_transport_chain.
- IDH3A wikiPageWikiLink Enzyme.
- IDH3A wikiPageWikiLink Gene.
- IDH3A wikiPageWikiLink Gene_duplication.
- IDH3A wikiPageWikiLink Glycolysis.
- IDH3A wikiPageWikiLink Heterotetramer.
- IDH3A wikiPageWikiLink Hypoxia-inducible_factors.
- IDH3A wikiPageWikiLink IDH1.
- IDH3A wikiPageWikiLink IDH2.
- IDH3A wikiPageWikiLink IDH3B.
- IDH3A wikiPageWikiLink IDH3G.
- IDH3A wikiPageWikiLink Isocitrate_dehydrogenase.
- IDH3A wikiPageWikiLink Isocitric_acid.
- IDH3A wikiPageWikiLink Isoelectric_point.
- IDH3A wikiPageWikiLink Ligand.
- IDH3A wikiPageWikiLink Major_depressive_disorder.
- IDH3A wikiPageWikiLink Mental_disorder.
- IDH3A wikiPageWikiLink Mitochondrion.
- IDH3A wikiPageWikiLink Nicotinamide_adenine_dinucleotide.
- IDH3A wikiPageWikiLink Nicotinamide_adenine_dinucleotide_phosphate.
- IDH3A wikiPageWikiLink Organic_redox_reaction.
- IDH3A wikiPageWikiLink Oxidative_phosphorylation.
- IDH3A wikiPageWikiLink Pathogenesis.
- IDH3A wikiPageWikiLink Peptide_sequence.
- IDH3A wikiPageWikiLink Protein_subunit.
- IDH3A wikiPageWikiLink Rate-determining_step.
- IDH3A wikiPageWikiLink Schizophrenia.
- IDH3A wikiPageWikiLink Subcellular_localization.
- IDH3A wikiPageWikiLink Substrate_(chemistry).
- IDH3A wikiPageWikiLink Warburg_effect.
- IDH3A wikiPageWikiLinkText "IDH3A".
- IDH3A requireManualInspection "no".
- IDH3A summaryText "Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD as the electron acceptor and the other NADP. Five isocitrate dehydrogenases have been reported: three NAD-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008]".
- IDH3A updateCitations "yes".
- IDH3A updatePage "yes".
- IDH3A updateProteinBox "yes".
- IDH3A updateSummary "yes".
- IDH3A wikiPageUsesTemplate Template:Cite_journal.
- IDH3A wikiPageUsesTemplate Template:Enzymes.
- IDH3A wikiPageUsesTemplate Template:Gene-15-stub.
- IDH3A wikiPageUsesTemplate Template:PBB.
- IDH3A wikiPageUsesTemplate Template:PBB_Controls.
- IDH3A wikiPageUsesTemplate Template:PBB_Further_reading.
- IDH3A wikiPageUsesTemplate Template:PBB_Summary.
- IDH3A wikiPageUsesTemplate Template:Portal_bar.
- IDH3A wikiPageUsesTemplate Template:Refbegin.
- IDH3A wikiPageUsesTemplate Template:Refend.
- IDH3A wikiPageUsesTemplate Template:Reflist.
- IDH3A wikiPageUsesTemplate threonine-specific_protein_kinases.
- IDH3A subject Category:EC_2.7.11.
- IDH3A hypernym Enzyme.
- IDH3A type Biomolecule.
- IDH3A type Protein.
- IDH3A type Thing.
- IDH3A type Q206229.
- IDH3A type Q8054.
- IDH3A comment "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3α) is an enzyme that in humans is encoded by the IDH3A gene.Isocitrate dehydrogenases (IDHs) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+).".
- IDH3A label "IDH3A".
- IDH3A sameAs Q18027551.
- IDH3A sameAs m.03g_t1t.
- IDH3A sameAs Q18027551.
- IDH3A wasDerivedFrom IDH3A?oldid=702233801.
- IDH3A isPrimaryTopicOf IDH3A.