Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Hypothetical_protein> ?p ?o }
Showing triples 1 to 51 of
51
with 100 triples per page.
- Hypothetical_protein abstract "In biochemistry, a hypothetical protein is a protein whose existence has been predicted, but for which there is a paucity of experimental evidence that it is expressed in vivo. Sequencing of several genomes has resulted in numerous predicted open reading frames to which functions cannot be readily assigned. These proteins, either orphan or conserved hypothetical proteins, make up ~ 20% to 40% of proteins encoded in each newly sequenced genome. Even when there is enough evidence that the product of the gene is expressed, by techniques such as microarray and mass-spectrometry, it is difficult to assign a function to it given its lack of identity to protein sequences with annotated biochemical function. Nowadays, most protein sequences are inferred from computational analysis of genomic DNA sequence. Hypothetical proteins are created by gene prediction software during genome analysis. When the bioinformatic tool used for the gene identification finds a large open reading frame without a characterised homologue in the protein database, it returns \"hypothetical protein\" as an annotation remark.The function of a hypothetical protein can be predicted by domain homology searches with various confidence levels. Conserved domains are available in the hypothetical proteins which need to be compared with the known family domains by which hypothetical protein could be classified into particular protein families even though they have not been in vivo investigated. The function of hypothetical protein could also be predicted by homology modelling, in which hypothetical protein has to align with known protein sequence whose three dimensional structure is known and by modelling method if structure predicted then the capability of hypothetical protein to function could be ascertained computationally.Further, approaches to annotate function to hypothetical proteins include determination of 3-dimensional structure of these proteins by structural genomics initiatives, understanding the nature and mode of prosthetic group/metal ion binding, fold similarity with other proteins of known functions and annotating possible catalytic site and regulatory site. Structure prediction with biochemical function assessment by screening for various substrate is another promising approach to annotate function".
- Hypothetical_protein wikiPageExternalLink get-entries?KW=Hypothetical%20protein.
- Hypothetical_protein wikiPageID "4635854".
- Hypothetical_protein wikiPageLength "6436".
- Hypothetical_protein wikiPageOutDegree "25".
- Hypothetical_protein wikiPageRevisionID "698384349".
- Hypothetical_protein wikiPageWikiLink Biochemistry.
- Hypothetical_protein wikiPageWikiLink Biocompx.
- Hypothetical_protein wikiPageWikiLink Biofrontiers.
- Hypothetical_protein wikiPageWikiLink Bioinformatics.
- Hypothetical_protein wikiPageWikiLink Biomirror.
- Hypothetical_protein wikiPageWikiLink Category:Bioinformatics.
- Hypothetical_protein wikiPageWikiLink Category:Proteins.
- Hypothetical_protein wikiPageWikiLink Current_Microbiology.
- Hypothetical_protein wikiPageWikiLink Domain_of_unknown_function.
- Hypothetical_protein wikiPageWikiLink Gene_prediction.
- Hypothetical_protein wikiPageWikiLink Genome.
- Hypothetical_protein wikiPageWikiLink IJSCB.
- Hypothetical_protein wikiPageWikiLink In_vivo.
- Hypothetical_protein wikiPageWikiLink Journal_of_Pharmacy_Research.
- Hypothetical_protein wikiPageWikiLink Nucleic_acid_sequence.
- Hypothetical_protein wikiPageWikiLink Open_reading_frame.
- Hypothetical_protein wikiPageWikiLink PLOS_ONE.
- Hypothetical_protein wikiPageWikiLink Prediction.
- Hypothetical_protein wikiPageWikiLink Proceedings_of_the_National_Academy_of_Sciences_of_the_United_States_of_America.
- Hypothetical_protein wikiPageWikiLink Protein.
- Hypothetical_protein wikiPageWikiLink Protein_domain.
- Hypothetical_protein wikiPageWikiLink Protein_superfamily.
- Hypothetical_protein wikiPageWikiLink Sequence_database.
- Hypothetical_protein wikiPageWikiLinkText "Hypothetical protein".
- Hypothetical_protein wikiPageWikiLinkText "hypothetical protein".
- Hypothetical_protein wikiPageUsesTemplate Template:Cite_journal.
- Hypothetical_protein wikiPageUsesTemplate Template:Protein-stub.
- Hypothetical_protein wikiPageUsesTemplate Template:Reflist.
- Hypothetical_protein subject Category:Bioinformatics.
- Hypothetical_protein subject Category:Proteins.
- Hypothetical_protein hypernym Protein.
- Hypothetical_protein type Biomolecule.
- Hypothetical_protein type Protein.
- Hypothetical_protein type Biomolecule.
- Hypothetical_protein type Biostatistic.
- Hypothetical_protein type Nutrient.
- Hypothetical_protein type Redirect.
- Hypothetical_protein comment "In biochemistry, a hypothetical protein is a protein whose existence has been predicted, but for which there is a paucity of experimental evidence that it is expressed in vivo. Sequencing of several genomes has resulted in numerous predicted open reading frames to which functions cannot be readily assigned. These proteins, either orphan or conserved hypothetical proteins, make up ~ 20% to 40% of proteins encoded in each newly sequenced genome.".
- Hypothetical_protein label "Hypothetical protein".
- Hypothetical_protein sameAs Q10855009.
- Hypothetical_protein sameAs 가설_단백질.
- Hypothetical_protein sameAs m.0cdst1.
- Hypothetical_protein sameAs Q10855009.
- Hypothetical_protein wasDerivedFrom Hypothetical_protein?oldid=698384349.
- Hypothetical_protein isPrimaryTopicOf Hypothetical_protein.