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- Hypotensive_transfusion_reaction abstract "A Hypotensive transfusion reaction or HTR is a rare condition that presents with low blood pressure associated with administration of blood products. The low blood pressure quickly resolves when the transfusion is stopped.HTRs are caused by the production of bradykinin produced through Factor XII activation by negatively charged surfaces such as filters. When mechanisms for the degradation of bradykinin are impaired, the peptide builds up and causes hypotension. Angiotensin converting enzyme (ACE) is primarily responsible for its degradation (75%) but can be inhibited by administration of blood pressure medications called ACE inhibitors. Polymorphisms in ACE or aminopeptidase P (APP), another enzyme responsible for bradykinin degradation (20%) may also contribute to HTRs.".
- Hypotensive_transfusion_reaction wikiPageID "27992782".
- Hypotensive_transfusion_reaction wikiPageLength "1046".
- Hypotensive_transfusion_reaction wikiPageOutDegree "12".
- Hypotensive_transfusion_reaction wikiPageRevisionID "653986619".
- Hypotensive_transfusion_reaction wikiPageWikiLink ACE_inhibitor.
- Hypotensive_transfusion_reaction wikiPageWikiLink Angiotensin-converting_enzyme.
- Hypotensive_transfusion_reaction wikiPageWikiLink Blood_pressure.
- Hypotensive_transfusion_reaction wikiPageWikiLink Blood_product.
- Hypotensive_transfusion_reaction wikiPageWikiLink Blood_transfusion.
- Hypotensive_transfusion_reaction wikiPageWikiLink Bradykinin.
- Hypotensive_transfusion_reaction wikiPageWikiLink Category:Hypotension.
- Hypotensive_transfusion_reaction wikiPageWikiLink Factor_XII.
- Hypotensive_transfusion_reaction wikiPageWikiLink Hypotension.
- Hypotensive_transfusion_reaction wikiPageWikiLink Peptide.
- Hypotensive_transfusion_reaction wikiPageWikiLink Polymorphism_(biology).
- Hypotensive_transfusion_reaction wikiPageWikiLink X-Pro_aminopeptidase.
- Hypotensive_transfusion_reaction wikiPageWikiLinkText "Hypotensive transfusion reaction".
- Hypotensive_transfusion_reaction wikiPageUsesTemplate Template:Refimprove.
- Hypotensive_transfusion_reaction wikiPageUsesTemplate Template:Reflist.
- Hypotensive_transfusion_reaction subject Category:Hypotension.
- Hypotensive_transfusion_reaction hypernym Condition.
- Hypotensive_transfusion_reaction type Disease.
- Hypotensive_transfusion_reaction comment "A Hypotensive transfusion reaction or HTR is a rare condition that presents with low blood pressure associated with administration of blood products. The low blood pressure quickly resolves when the transfusion is stopped.HTRs are caused by the production of bradykinin produced through Factor XII activation by negatively charged surfaces such as filters. When mechanisms for the degradation of bradykinin are impaired, the peptide builds up and causes hypotension.".
- Hypotensive_transfusion_reaction label "Hypotensive transfusion reaction".
- Hypotensive_transfusion_reaction sameAs Q5961215.
- Hypotensive_transfusion_reaction sameAs m.0ch5k6y.
- Hypotensive_transfusion_reaction sameAs Q5961215.
- Hypotensive_transfusion_reaction wasDerivedFrom Hypotensive_transfusion_reaction?oldid=653986619.
- Hypotensive_transfusion_reaction isPrimaryTopicOf Hypotensive_transfusion_reaction.