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- Hypereosinophilia abstract "Hypereosinophilia or hypereosinophilic syndrome is a disease characterised by a marked increase in the eosinophil count in the bloodstream.The eosinophil count in human blood is normally 0.4 × 109/L (0.1 - 0.6) and results from a balance between production of eosinophils and emigration through post-capillary venules (Yamaguchi et al. 1991). Eosinophils are only a small minority of peripheral blood leucocytes and in normal subjects, most are found in the tissues of the lung and gastro-intestinal tract (Beeken et al. 1987). Blood eosinophil counts are arbitrarily classified as mild - between 0.6 to 1.5 × 109/L; moderate between 1.5 to 5 × 109/L and severe when greater than 5 × 109/L.An elevated blood eosinophil count may be associated with a number of reactive conditions and with clonal disorders of the bone marrow. However, when the blood eosinophil count is persistently greater than 1.5 × 109 /L, for a period of more than six months, damage to end organs such as the heart, lungs, skin, joints and nervous system can be demonstrated, and in the absence of any clonal or reactive cause, the term idiopathic hypereosinophilic syndrome (HES) is used. The three defining criteria of HES are therefore: Eosinophil count persistently greater than 1.5 × 109/L Damage to end-organs No ascertainable cause for the eosinophilia and no evidence of clonality.There are three categories of blood eosinophilia: Reactive (non-clonal) eosinophilia: infections, parasitic infestations, asthma and allergies, respiratory diseases, cytokine infusions, vasculitides, non-haematological malignant diseases, drug reactions and connective tissue diseases, Hodgkin's and non-Hodgkin's lymphomas are included here as the eosinophils have not been shown to be clonal. Clonal Disorders of the Bone Marrow associated with eosinophilia: Acute and chronic eosinophilic leukaemia, chronic myeloid leukaemia, polycythaemia rubra vera, essential thrombocythaemia, acute myeloid leukaemia. Chromosome 16 variants, the 8p11 myeloproliferative syndrome (EMS) and T lymphoblastic lymphoma with eosinophilia, acute lymphoblastic leukaemia, myelodysplastic disorders (MDS) with eosinophilia, systemic mastocytosis and acute lymphoblastic leukaemia (Bain 1996). HES: After exclusion of the above two categories, cases of persistent, unexplained eosinophilia fall into the category of HES.↑".
- Hypereosinophilia wikiPageExternalLink hypereosinophilic-syndrome.
- Hypereosinophilia wikiPageExternalLink hypereosinophilic-syndrome.aspx.
- Hypereosinophilia wikiPageExternalLink www.hypereosinophilia.info.
- Hypereosinophilia wikiPageExternalLink con-20036168.
- Hypereosinophilia wikiPageID "6878422".
- Hypereosinophilia wikiPageLength "3581".
- Hypereosinophilia wikiPageOutDegree "17".
- Hypereosinophilia wikiPageRevisionID "687746586".
- Hypereosinophilia wikiPageWikiLink 8p11_myeloproliferative_syndrome.
- Hypereosinophilia wikiPageWikiLink Acute_myeloid_leukemia.
- Hypereosinophilia wikiPageWikiLink Category:Monocyte_and_granulocyte_disorders.
- Hypereosinophilia wikiPageWikiLink Chromosome_16_variants.
- Hypereosinophilia wikiPageWikiLink Chronic_myelogenous_leukemia.
- Hypereosinophilia wikiPageWikiLink Clonality.
- Hypereosinophilia wikiPageWikiLink Cytokine_infusions.
- Hypereosinophilia wikiPageWikiLink EMedicine.
- Hypereosinophilia wikiPageWikiLink Eosinophil_granulocyte.
- Hypereosinophilia wikiPageWikiLink Hodgkins_lymphoma.
- Hypereosinophilia wikiPageWikiLink Hypereosinophilic_syndrome.
- Hypereosinophilia wikiPageWikiLink Non-Hodgkin_lymphoma.
- Hypereosinophilia wikiPageWikiLink Polycythemia_vera.
- Hypereosinophilia wikiPageWikiLink T_lymphoblastic_lymphoma_with_eosinophilia.
- Hypereosinophilia wikiPageWikiLink Thrombocytosis.
- Hypereosinophilia wikiPageWikiLink White_blood_cell.
- Hypereosinophilia wikiPageWikiLinkText "Hypereosinophilia".
- Hypereosinophilia wikiPageWikiLinkText "an abnormally high level of eosinophils".
- Hypereosinophilia wikiPageWikiLinkText "hypereosinophilia".
- Hypereosinophilia wikiPageUsesTemplate Template:EMedicine2.
- Hypereosinophilia wikiPageUsesTemplate Template:More_footnotes.
- Hypereosinophilia wikiPageUsesTemplate Template:Reflist.
- Hypereosinophilia subject Category:Monocyte_and_granulocyte_disorders.
- Hypereosinophilia hypernym Disease.
- Hypereosinophilia type Disease.
- Hypereosinophilia type Disorder.
- Hypereosinophilia comment "Hypereosinophilia or hypereosinophilic syndrome is a disease characterised by a marked increase in the eosinophil count in the bloodstream.The eosinophil count in human blood is normally 0.4 × 109/L (0.1 - 0.6) and results from a balance between production of eosinophils and emigration through post-capillary venules (Yamaguchi et al. 1991).".
- Hypereosinophilia label "Hypereosinophilia".
- Hypereosinophilia sameAs Q2305206.
- Hypereosinophilia sameAs m.0gty88.
- Hypereosinophilia sameAs Q2305206.
- Hypereosinophilia wasDerivedFrom Hypereosinophilia?oldid=687746586.
- Hypereosinophilia isPrimaryTopicOf Hypereosinophilia.