Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Hydroxyzine> ?p ?o }
- Hydroxyzine abstract "Hydroxyzine (/haɪˈdrɒksᵻziːn/; sold as Vistaril, Atarax) is a first-generation antihistamine of the diphenylmethane and piperazine class. It was first synthesized by Union Chimique Belge in 1956 and was marketed by Pfizer in the United States later the same year, and is still in widespread use today.Due to its antagonistic effects on several receptor systems in the brain, hydroxyzine has strong anxiolytic and mild antiobsessive as well as antipsychotic properties. Today it is used primarily for the symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Because of its antihistamine effects it can also be used for the treatment of severe cases of itching, hyperalgesia and motion sickness-induced nausea, it has also been used in some cases to relieve the effects of opioid withdrawal. Even though it is an effective sedative, hypnotic, and anxiolytic, it shares virtually none of the abuse, dependence, addiction, and toxicity potential of other drugs used for the same range of therapeutic reasons. Hydroxyzine has also been used to potentiate the analgesia of opioids and to alleviate some of their side effects, such as itching, nausea, and vomiting.Hydroxyzine preparations usually require a doctor's prescription. The drug is available in two formulations, the pamoate and the dihydrochloride or hydrochloride salts. Vistaril, Equipose, Masmoran, and Paxistil are preparations of the pamoate salt, while Atarax, Alamon, Aterax, Durrax, Tran-Q, Orgatrax, Quiess, and Tranquizine are of the hydrochloride salt.Other drugs related to hydroxyzine are cyclizine, buclizine, and meclizine, and they share all or most of the benefits, indications, contraindications, cautions, and side effects of hydroxyzine. The second-generation antihistamine cetirizine is in fact one of the metabolites of hydroxyzine produced in the human body. Unlike hydroxyzine, cetirizine is not reported to appreciably cross the blood-brain barrier, but it has been reported to be associated with dystonic reactions as well as sedation. Therefore, it has a narrower spectrum of effects, making it an effective antihistamine but removing some or all of the anxiolytic and other psychoactive properties, but it may cause dystonic reactions and drowsiness in some patients.".
- Hydroxyzine atcPrefix "N05".
- Hydroxyzine atcSuffix "BB01".
- Hydroxyzine casNumber "68-88-2".
- Hydroxyzine chEBI "5818".
- Hydroxyzine drugbank "DB00557".
- Hydroxyzine fdaUniiCode "30S50YM8OG".
- Hydroxyzine iupacName "(±)-2-(2-{4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl}ethoxy)ethanol".
- Hydroxyzine pubchem "3658".
- Hydroxyzine thumbnail Hydroxyzine.svg?width=300.
- Hydroxyzine wikiPageExternalLink 11795s16.pdf.
- Hydroxyzine wikiPageExternalLink monograph?cid=med&drugid=6144&drugname=Vistaril+Oral&monotype=monograph&print=1.
- Hydroxyzine wikiPageExternalLink uspi_vistaril.pdf.
- Hydroxyzine wikiPageExternalLink hydrox_ids.htm.
- Hydroxyzine wikiPageExternalLink dpdirect.jsp?name=Hydroxyzine.
- Hydroxyzine wikiPageExternalLink ABSTRACT?SRETRY=0.
- Hydroxyzine wikiPageExternalLink ABSTRACT?CRETRY=1&SRETRY=0.
- Hydroxyzine wikiPageExternalLink ABSTRACT.
- Hydroxyzine wikiPageID "733497".
- Hydroxyzine wikiPageLength "28509".
- Hydroxyzine wikiPageOutDegree "123".
- Hydroxyzine wikiPageRevisionID "707114062".
- Hydroxyzine wikiPageWikiLink 5-HT2A_receptor.
- Hydroxyzine wikiPageWikiLink Addiction.
- Hydroxyzine wikiPageWikiLink Alcohol_dehydrogenase.
- Hydroxyzine wikiPageWikiLink Allergy.
- Hydroxyzine wikiPageWikiLink Alpha-1_adrenergic_receptor.
- Hydroxyzine wikiPageWikiLink Anticholinergic.
- Hydroxyzine wikiPageWikiLink Antihistamine.
- Hydroxyzine wikiPageWikiLink Antipsychotic.
- Hydroxyzine wikiPageWikiLink Anxiety.
- Hydroxyzine wikiPageWikiLink Anxiolytic.
- Hydroxyzine wikiPageWikiLink Athetosis.
- Hydroxyzine wikiPageWikiLink Atopic_dermatitis.
- Hydroxyzine wikiPageWikiLink Atropine.
- Hydroxyzine wikiPageWikiLink Barbiturate.
- Hydroxyzine wikiPageWikiLink Benzodiazepine.
- Hydroxyzine wikiPageWikiLink Blood–brain_barrier.
- Hydroxyzine wikiPageWikiLink Bromazepam.
- Hydroxyzine wikiPageWikiLink Buclizine.
- Hydroxyzine wikiPageWikiLink CYP3A4.
- Hydroxyzine wikiPageWikiLink CYP3A5.
- Hydroxyzine wikiPageWikiLink Category:Alcohols.
- Hydroxyzine wikiPageWikiLink Category:Antiemetics.
- Hydroxyzine wikiPageWikiLink Category:Anxiolytics.
- Hydroxyzine wikiPageWikiLink Category:Belgian_inventions.
- Hydroxyzine wikiPageWikiLink Category:Chloroarenes.
- Hydroxyzine wikiPageWikiLink Category:Ethers.
- Hydroxyzine wikiPageWikiLink Category:H1_receptor_antagonists.
- Hydroxyzine wikiPageWikiLink Category:Piperazines.
- Hydroxyzine wikiPageWikiLink Category:Sedatives.
- Hydroxyzine wikiPageWikiLink Central_nervous_system.
- Hydroxyzine wikiPageWikiLink Cetirizine.
- Hydroxyzine wikiPageWikiLink Contact_dermatitis.
- Hydroxyzine wikiPageWikiLink Cyclizine.
- Hydroxyzine wikiPageWikiLink Dialysis.
- Hydroxyzine wikiPageWikiLink Diphenylmethane.
- Hydroxyzine wikiPageWikiLink Dopamine_receptor_D2.
- Hydroxyzine wikiPageWikiLink Dosage_form.
- Hydroxyzine wikiPageWikiLink Elizabeth_Wurtzel.
- Hydroxyzine wikiPageWikiLink Ethanol.
- Hydroxyzine wikiPageWikiLink Etodroxizine.
- Hydroxyzine wikiPageWikiLink Feces.
- Hydroxyzine wikiPageWikiLink Food_and_Drug_Administration.
- Hydroxyzine wikiPageWikiLink Formulation.
- Hydroxyzine wikiPageWikiLink Gastrointestinal_tract.
- Hydroxyzine wikiPageWikiLink Generalized_anxiety_disorder.
- Hydroxyzine wikiPageWikiLink H1_antagonist.
- Hydroxyzine wikiPageWikiLink Hemolysis.
- Hydroxyzine wikiPageWikiLink Histamine.
- Hydroxyzine wikiPageWikiLink Histamine_H1_receptor.
- Hydroxyzine wikiPageWikiLink Hydrochloride.
- Hydroxyzine wikiPageWikiLink Hyoscine_hydrobromide.
- Hydroxyzine wikiPageWikiLink Hyperalgesia.
- Hydroxyzine wikiPageWikiLink Hypersensitivity.
- Hydroxyzine wikiPageWikiLink Hypnotic.
- Hydroxyzine wikiPageWikiLink Hypotension.
- Hydroxyzine wikiPageWikiLink In_vivo.
- Hydroxyzine wikiPageWikiLink Intramuscular_injection.
- Hydroxyzine wikiPageWikiLink Inverse_agonist.
- Hydroxyzine wikiPageWikiLink Itch.
- Hydroxyzine wikiPageWikiLink John_Wiley_&_Sons.
- Hydroxyzine wikiPageWikiLink Learned_helplessness.
- Hydroxyzine wikiPageWikiLink Lithium_(medication).
- Hydroxyzine wikiPageWikiLink Liver.
- Hydroxyzine wikiPageWikiLink Lorazepam.
- Hydroxyzine wikiPageWikiLink Love_&_Other_Drugs.
- Hydroxyzine wikiPageWikiLink McGraw-Hill_Education.
- Hydroxyzine wikiPageWikiLink Mechanism_of_action.
- Hydroxyzine wikiPageWikiLink Meclizine.
- Hydroxyzine wikiPageWikiLink Medical_prescription.
- Hydroxyzine wikiPageWikiLink Metabolite.
- Hydroxyzine wikiPageWikiLink Motion_sickness.
- Hydroxyzine wikiPageWikiLink Mouth.
- Hydroxyzine wikiPageWikiLink Muscarinic_acetylcholine_receptor.
- Hydroxyzine wikiPageWikiLink Muscarinic_antagonist.
- Hydroxyzine wikiPageWikiLink Nausea.
- Hydroxyzine wikiPageWikiLink Neurosis.
- Hydroxyzine wikiPageWikiLink Obsessive–compulsive_disorder.
- Hydroxyzine wikiPageWikiLink Opioid_addiction_and_dependence.