Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Hereditary_diffuse_leukoencephalopathy_with_spheroids> ?p ?o }
- Hereditary_diffuse_leukoencephalopathy_with_spheroids abstract "Hereditary diffuse leukoencephalopathy with spheroids (HDLS) is a rare adult onset autosomal dominant disorder characterized by cerebral white matter degeneration with demyelination and axonal spheroids leading to progressive cognitive and motor dysfunction. Spheroids are axonal swellings with discontinuous or absence of myelin sheaths. It is believed that the disease arises from primary microglial dysfunction that leads to secondary disruption of axonal integrity, neuroaxonal damage, and focal axonal spheroids leading to demyelination. Spheroids in HDLS resemble to some extent those produced by shear stress in a closed head injury with damage to axons, causing them to swell due to blockage of axoplasmic transport. In addition to trauma, axonal spheroids can be found in aged brain, stroke, and in other degenerative diseases. In HDLS, it is uncertain whether demyelination occurs prior to the axonal spheroids or what triggers neurodegeneration after apparently normal brain and white matter development, although genetic deficits suggest that demyelination and axonal pathology may be secondary to microglial dysfunction. The clinical syndrome in patients with HDLS is not specific and it can be mistaken for Alzheimer's disease, frontotemporal dementia, atypical Parkinsonism, multiple sclerosis, or corticobasal degeneration.".
- Hereditary_diffuse_leukoencephalopathy_with_spheroids omim "221820".
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageID "34231074".
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageLength "18047".
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageOutDegree "92".
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageRevisionID "591709236".
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Adrenoleukodystrophy.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Alcoholism.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Alzheimers_disease.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Amino_acid.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Apraxia.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Astrocyte.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Ataxia.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Autopsy.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Autosome.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Axon.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Axoplasmic_transport.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Basal_ganglia.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Brainstem.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Category:Genetic_disorders.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Category:Neurological_disorders.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Cerebellum.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Cerebrum.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Closed_head_injury.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Colony-stimulating_factor.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Colony_stimulating_factor_1_receptor.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Consortium.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Corticobasal_degeneration.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Deletion_(genetics).
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Dementia.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Demyelinating_disease.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Depression_(mood).
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Dominance_(genetics).
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Executive_dysfunction.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Exon.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Fibril.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Frontotemporal_dementia.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Gliosis.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink H&E_stain.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Histology.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Immunohistochemistry.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Intracellular.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Kinase.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Krabbe_disease.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Lateral_ventricles.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Leukodystrophy.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Leukoencephalopathy_with_vanishing_white_matter.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Macrophage.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Magnetic_resonance_imaging.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Mayo_Clinic.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Medical_history.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Metachromatic_leukodystrophy.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Microcephaly.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Midbrain.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Mini–mental_state_examination.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Missense_mutation.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Multiple_sclerosis.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Muteness.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Myelin.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Neocortex.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Neurodegeneration.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Neuropathology.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Neuropsychiatry.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Nucleotide.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Oligodendrocyte.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Paraffin_wax.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Paraplegia.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Parkinsonism.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Pathogenesis.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Pathology.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Polycystic_lipomembranous_osteodysplasia_with_sclerosing_leukoencephalopathy.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Pons.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Proband.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Pyramidal_tracts.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Rarefaction.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Sex_linkage.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Shear_stress.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Signal_transduction.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Spastic_hemiplegia.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Spinal_cord.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Splice_site_mutation.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Substance_abuse.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Sweden.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink TREM2.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink TYROBP.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Tetraplegia.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Thalamus.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Tyrosine.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Ubiquitin.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink Unified_Parkinsons_disease_rating_scale.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink White_matter.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLink File:Leukencephalopathy.PNG.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageWikiLinkText "hereditary diffuse leukoencephalopathy with spheroids".
- Hereditary_diffuse_leukoencephalopathy_with_spheroids name "Hereditary diffuse leukoencephalopathy with spheroids".
- Hereditary_diffuse_leukoencephalopathy_with_spheroids omim "221820".
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageUsesTemplate Template:Infobox_disease.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids wikiPageUsesTemplate Template:OMIM2.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids subject Category:Genetic_disorders.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids subject Category:Neurological_disorders.
- Hereditary_diffuse_leukoencephalopathy_with_spheroids hypernym Disorder.