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- suppressor_ratio abstract "The T-Lymphocyte Helper/Suppressor Profile (Helper/Suppressor ratio, T4:T8 ratio, CD4:CD8 ratio) is a basic laboratory test in which the percentage of CD3-positive lymphocytes in the blood positive for CD4 (T helper cells) and CD8 (a class of regulatory T cells) are counted and compared. Normal values (95% confidence intervals) are approximately 30-60% CD4 and 10-30% CD8 depending on age (ratio 0.9 to 3.7 in adults). One reason for abnormal results is the loss of CD4-positive cells to the Human Immunodeficiency Virus [HIV] infection.The loss of CD4-positive cells to HIV infection can result in various distortions in the ratio, as in the initial period, production of HIV specific CD8 positive cells will cause a large fall in the ratio, but subsequent immunosuppression over time may lead to overall non production of immune cells and inversion of the ratio. It has been shown that the degree of inversion of this ratio in individuals on antiretroviral therapy is indicative of the age of the infection and independently predictive of mortality associated with non HIV events.".
- suppressor_ratio wikiPageID "12846099".
- suppressor_ratio wikiPageLength "1659".
- suppressor_ratio wikiPageOutDegree "7".
- suppressor_ratio wikiPageRevisionID "590869691".
- suppressor_ratio wikiPageWikiLink CD3_(immunology).
- suppressor_ratio wikiPageWikiLink CD4.
- suppressor_ratio wikiPageWikiLink CD8.
- suppressor_ratio wikiPageWikiLink Category:Blood_tests.
- suppressor_ratio wikiPageWikiLink Lymphocyte.
- suppressor_ratio wikiPageWikiLink Regulatory_T_cell.
- suppressor_ratio wikiPageWikiLink T_helper_cell.
- suppressor_ratio wikiPageWikiLinkText "Helper/suppressor ratio".
- suppressor_ratio wikiPageWikiLinkText "helper/suppressor ratio".
- suppressor_ratio wikiPageWikiLinkText "helper/suppressor".
- suppressor_ratio wikiPageUsesTemplate Template:Immunology-stub.
- suppressor_ratio wikiPageUsesTemplate Template:Reflist.
- suppressor_ratio subject Category:Blood_tests.
- suppressor_ratio hypernym Test.
- suppressor_ratio type Cricketer.
- suppressor_ratio comment "The T-Lymphocyte Helper/Suppressor Profile (Helper/Suppressor ratio, T4:T8 ratio, CD4:CD8 ratio) is a basic laboratory test in which the percentage of CD3-positive lymphocytes in the blood positive for CD4 (T helper cells) and CD8 (a class of regulatory T cells) are counted and compared. Normal values (95% confidence intervals) are approximately 30-60% CD4 and 10-30% CD8 depending on age (ratio 0.9 to 3.7 in adults).".
- suppressor_ratio label "Helper/suppressor ratio".
- suppressor_ratio sameAs Q5710202.
- suppressor_ratio sameAs m.0ggcb6.
- suppressor_ratio sameAs Q5710202.
- suppressor_ratio wasDerivedFrom suppressor_ratio?oldid=590869691.
- suppressor_ratio isPrimaryTopicOf suppressor_ratio.