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- HYAL2 abstract "Hyaluronidase-2 is an enzyme that in humans is encoded by the HYAL2 gene.This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. Varying functions have been described for this protein. It has been described as a lysosomal hyaluronidase which is active at a pH below 4 and specifically hydrolyzes high molecular weight hyaluronan. It has also been described as a GPI-anchored cell surface protein which does not display hyaluronidase activity but does serve as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.".
- HYAL2 entrezgene "8692".
- HYAL2 wikiPageID "14769849".
- HYAL2 wikiPageLength "9853".
- HYAL2 wikiPageOutDegree "2".
- HYAL2 wikiPageRevisionID "678282405".
- HYAL2 wikiPageWikiLink Enzyme.
- HYAL2 wikiPageWikiLink Gene.
- HYAL2 wikiPageWikiLinkText "HYAL2".
- HYAL2 requireManualInspection "no".
- HYAL2 summaryText "300.0".
- HYAL2 updateCitations "yes".
- HYAL2 updatePage "yes".
- HYAL2 updateProteinBox "yes".
- HYAL2 updateSummary "yes".
- HYAL2 wikiPageUsesTemplate Template:Cite_journal.
- HYAL2 wikiPageUsesTemplate Template:Gene-3-stub.
- HYAL2 wikiPageUsesTemplate Template:PBB.
- HYAL2 wikiPageUsesTemplate Template:PBB_Controls.
- HYAL2 wikiPageUsesTemplate Template:PBB_Further_reading.
- HYAL2 wikiPageUsesTemplate Template:PBB_Summary.
- HYAL2 wikiPageUsesTemplate Template:Refbegin.
- HYAL2 wikiPageUsesTemplate Template:Refend.
- HYAL2 wikiPageUsesTemplate Template:Reflist.
- HYAL2 wikiPageUsesTemplate Template:Underlinked.
- HYAL2 hypernym Enzyme.
- HYAL2 type Biomolecule.
- HYAL2 type Protein.
- HYAL2 type Thing.
- HYAL2 type Q206229.
- HYAL2 type Q8054.
- HYAL2 comment "Hyaluronidase-2 is an enzyme that in humans is encoded by the HYAL2 gene.This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. Varying functions have been described for this protein.".
- HYAL2 label "HYAL2".
- HYAL2 sameAs Q18033221.
- HYAL2 sameAs m.03gxd3c.
- HYAL2 sameAs Q18033221.
- HYAL2 wasDerivedFrom HYAL2?oldid=678282405.
- HYAL2 isPrimaryTopicOf HYAL2.