Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/HT-2157> ?p ?o }
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- HT-2157 abstract "HT-2157 (former code name SNAP-37889) is a drug which acts as a selective non-peptide antagonist for the receptor GAL-3, which is usually activated by the neuropeptide galanin. Blocking this receptor with HT-2157 produced increased serotonin release, as well as producing antidepressant and anxiolytic effects in animal studies, and it was also being researched for treatment of cognitive dysfunction. All human clinical trials were terminated due to safety concerns however, and new GAL-3 antagonists are now being sought instead.".
- HT-2157 atcPrefix "none".
- HT-2157 casNumber "303149-14-6".
- HT-2157 iupacName "1-phenyl-3-[3-(trifluoromethyl)phenyl]iminoindol-2-one".
- HT-2157 pubchem "1471834".
- HT-2157 thumbnail HT-2157_structure.png?width=300.
- HT-2157 wikiPageID "44748690".
- HT-2157 wikiPageLength "2093".
- HT-2157 wikiPageOutDegree "10".
- HT-2157 wikiPageRevisionID "667233745".
- HT-2157 wikiPageWikiLink Antidepressant.
- HT-2157 wikiPageWikiLink Anxiolytic.
- HT-2157 wikiPageWikiLink Category:Peptides.
- HT-2157 wikiPageWikiLink Category:Receptor_antagonists.
- HT-2157 wikiPageWikiLink Cognitive_disorder.
- HT-2157 wikiPageWikiLink Galanin.
- HT-2157 wikiPageWikiLink Galanin_receptor_3.
- HT-2157 wikiPageWikiLink Neuropeptide.
- HT-2157 wikiPageWikiLink Receptor_antagonist.
- HT-2157 wikiPageWikiLink Serotonin.
- HT-2157 wikiPageWikiLinkText "HT-2157".
- HT-2157 atcPrefix "none".
- HT-2157 c "21".
- HT-2157 casNumber "303149".
- HT-2157 f "3".
- HT-2157 h "13".
- HT-2157 iupacName "1".
- HT-2157 iupharLigand "6126".
- HT-2157 molecularWeight "366.335".
- HT-2157 n "2".
- HT-2157 o "1".
- HT-2157 pubchem "1471834".
- HT-2157 smiles "c14ccccc4ncc1=N\ccccc2CF".
- HT-2157 wikiPageUsesTemplate Template:Drugbox.
- HT-2157 wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- HT-2157 wikiPageUsesTemplate Template:Neuropeptidergics.
- HT-2157 wikiPageUsesTemplate Template:Reflist.
- HT-2157 subject Category:Peptides.
- HT-2157 subject Category:Receptor_antagonists.
- HT-2157 hypernym Drug.
- HT-2157 type ChemicalSubstance.
- HT-2157 type Drug.
- HT-2157 type ChemicalObject.
- HT-2157 type Thing.
- HT-2157 type Q8386.
- HT-2157 comment "HT-2157 (former code name SNAP-37889) is a drug which acts as a selective non-peptide antagonist for the receptor GAL-3, which is usually activated by the neuropeptide galanin. Blocking this receptor with HT-2157 produced increased serotonin release, as well as producing antidepressant and anxiolytic effects in animal studies, and it was also being researched for treatment of cognitive dysfunction.".
- HT-2157 label "HT-2157".
- HT-2157 sameAs Q19597525.
- HT-2157 sameAs m.012hdy1p.
- HT-2157 sameAs Q19597525.
- HT-2157 wasDerivedFrom HT-2157?oldid=667233745.
- HT-2157 depiction HT-2157_structure.png.
- HT-2157 isPrimaryTopicOf HT-2157.