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- HMA_domain abstract "In molecular biology, the HMA domain (heavy-metal-associated domain) is a conserved protein domain found in a number of heavy metal transport or detoxification proteins.Proteins that transport heavy metals in micro-organisms and mammals share similarities in their sequences and structures. These proteins provide an important focus for research, some being involved in bacterial resistance to toxic metals, such as lead and cadmium, while others are involved in inherited human syndromes, such as Wilson's and Menke's diseases.The HMA domain, contains two conserved cysteines that are probably involved in metal binding. The fourth HMA domain of the Menke's copper transporting ATPase shows a well-defined structure comprising a four-stranded antiparallel beta-sheet and two alpha helices packed in an alpha-beta sandwich fold. This fold is common to other domains and is classified as \"ferredoxin-like\".".
- HMA_domain symbol "HMA".
- HMA_domain thumbnail PDB_1mwz_EBI.jpg?width=300.
- HMA_domain wikiPageID "33458450".
- HMA_domain wikiPageLength "2481".
- HMA_domain wikiPageOutDegree "31".
- HMA_domain wikiPageRevisionID "591673286".
- HMA_domain wikiPageWikiLink ATP7A.
- HMA_domain wikiPageWikiLink Alpha_helix.
- HMA_domain wikiPageWikiLink Antiparallel_(biochemistry).
- HMA_domain wikiPageWikiLink Bacteria.
- HMA_domain wikiPageWikiLink Beta_sheet.
- HMA_domain wikiPageWikiLink Biomolecular_structure.
- HMA_domain wikiPageWikiLink Cadmium.
- HMA_domain wikiPageWikiLink Category:Protein_domains.
- HMA_domain wikiPageWikiLink Conserved_sequence.
- HMA_domain wikiPageWikiLink Cysteine.
- HMA_domain wikiPageWikiLink Detoxification.
- HMA_domain wikiPageWikiLink Ferredoxin.
- HMA_domain wikiPageWikiLink Homo_sapiens.
- HMA_domain wikiPageWikiLink Lead.
- HMA_domain wikiPageWikiLink Mammal.
- HMA_domain wikiPageWikiLink Menkes_disease.
- HMA_domain wikiPageWikiLink Microorganism.
- HMA_domain wikiPageWikiLink Molecular_binding.
- HMA_domain wikiPageWikiLink Protein.
- HMA_domain wikiPageWikiLink Protein_domain.
- HMA_domain wikiPageWikiLink Protein_folding.
- HMA_domain wikiPageWikiLink Protein_structure.
- HMA_domain wikiPageWikiLink Sequence_(biology).
- HMA_domain wikiPageWikiLink Toxic_heavy_metal.
- HMA_domain wikiPageWikiLink Toxicity.
- HMA_domain wikiPageWikiLink Transport_protein.
- HMA_domain wikiPageWikiLink Wilsons_disease.
- HMA_domain wikiPageWikiLinkText "heavy metal-binding domains".
- HMA_domain caption "solution structure of the n-terminal domain of znta in the zn-form".
- HMA_domain interpro "IPR006121".
- HMA_domain name "Heavy-metal-associated domain".
- HMA_domain pfam "PF00403".
- HMA_domain prosite "PDOC00804".
- HMA_domain scop "2".
- HMA_domain symbol "HMA".
- HMA_domain tcdb "9".
- HMA_domain wikiPageUsesTemplate Template:Infobox_protein_family.
- HMA_domain wikiPageUsesTemplate Template:InterPro_content.
- HMA_domain wikiPageUsesTemplate Template:Reflist.
- HMA_domain subject Category:Protein_domains.
- HMA_domain hypernym Domain.
- HMA_domain type Biomolecule.
- HMA_domain type Protein.
- HMA_domain type Chemical.
- HMA_domain type Domain.
- HMA_domain type Thing.
- HMA_domain type Q206229.
- HMA_domain type Q8054.
- HMA_domain comment "In molecular biology, the HMA domain (heavy-metal-associated domain) is a conserved protein domain found in a number of heavy metal transport or detoxification proteins.Proteins that transport heavy metals in micro-organisms and mammals share similarities in their sequences and structures.".
- HMA_domain label "HMA domain".
- HMA_domain sameAs Q5630682.
- HMA_domain sameAs m.0h94mh8.
- HMA_domain sameAs Q5630682.
- HMA_domain wasDerivedFrom HMA_domain?oldid=591673286.
- HMA_domain depiction PDB_1mwz_EBI.jpg.
- HMA_domain isPrimaryTopicOf HMA_domain.