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- HES1 abstract "Transcription factor HES1 (hairy and enhancer of split-1) is a protein that is encoded by the Hes1 gene, and is the mammalian homolog of the hairy gene in Drosophila. HES1 is one of the seven members of the Hes gene family (HES1-7). Hes genes code nuclear proteins that suppress transcription.This protein belongs to the basic helix-loop-helix (bHLH) family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box promoter region rather than the canonical enhancer box (E-box). As a member of the bHLH family, it is a transcriptional repressor that influences cell proliferation and differentiation in embryogenesis. HES1 regulates its own expression via a negative feedback loop, and oscillates with approximately 2-hour periodicity.".
- HES1 entrezgene "3280".
- HES1 wikiPageID "14761897".
- HES1 wikiPageLength "22201".
- HES1 wikiPageOutDegree "51".
- HES1 wikiPageRevisionID "640532689".
- HES1 wikiPageWikiLink ASCL1.
- HES1 wikiPageWikiLink ATOH1.
- HES1 wikiPageWikiLink Alagille_syndrome.
- HES1 wikiPageWikiLink Astrocyte.
- HES1 wikiPageWikiLink Basic_helix-loop-helix.
- HES1 wikiPageWikiLink Brachyury.
- HES1 wikiPageWikiLink C-terminus.
- HES1 wikiPageWikiLink Category:Transcription_factors.
- HES1 wikiPageWikiLink Cholangiocyte.
- HES1 wikiPageWikiLink DNA_methylation.
- HES1 wikiPageWikiLink Delta-like_1.
- HES1 wikiPageWikiLink Drosophila.
- HES1 wikiPageWikiLink E-box.
- HES1 wikiPageWikiLink Embryogenesis.
- HES1 wikiPageWikiLink Enteroendocrine_cell.
- HES1 wikiPageWikiLink Epigenetic_regulation_of_neurogenesis.
- HES1 wikiPageWikiLink FGF5.
- HES1 wikiPageWikiLink Gene.
- HES1 wikiPageWikiLink Goblet_cell.
- HES1 wikiPageWikiLink HEY1.
- HES1 wikiPageWikiLink HEY2.
- HES1 wikiPageWikiLink Hepatocyte.
- HES1 wikiPageWikiLink Human_gastrointestinal_tract.
- HES1 wikiPageWikiLink Intestinal_gland.
- HES1 wikiPageWikiLink JAG1.
- HES1 wikiPageWikiLink Knockout_mouse.
- HES1 wikiPageWikiLink Negative_feedback.
- HES1 wikiPageWikiLink Nervous_system.
- HES1 wikiPageWikiLink Nestin_(protein).
- HES1 wikiPageWikiLink Neuroepithelial_cell.
- HES1 wikiPageWikiLink Neurogenins.
- HES1 wikiPageWikiLink Notch_signaling_pathway.
- HES1 wikiPageWikiLink Orange_carotenoid_N-terminal_domain.
- HES1 wikiPageWikiLink PAX6.
- HES1 wikiPageWikiLink PTF1A.
- HES1 wikiPageWikiLink Pancreatic_islets.
- HES1 wikiPageWikiLink Paneth_cell.
- HES1 wikiPageWikiLink Progenitor_cell.
- HES1 wikiPageWikiLink Proline.
- HES1 wikiPageWikiLink Protein.
- HES1 wikiPageWikiLink Protein_dimer.
- HES1 wikiPageWikiLink Protein_domain.
- HES1 wikiPageWikiLink Protein–protein_interaction.
- HES1 wikiPageWikiLink RBPJ.
- HES1 wikiPageWikiLink Radial_glial_cell.
- HES1 wikiPageWikiLink Real-time_polymerase_chain_reaction.
- HES1 wikiPageWikiLink Sirtuin_1.
- HES1 wikiPageWikiLink Stem_cell.
- HES1 wikiPageWikiLink Subventricular_zone.
- HES1 wikiPageWikiLink TLE2.
- HES1 wikiPageWikiLink Transcription_factor.
- HES1 wikiPageWikiLinkText "HES1 gene".
- HES1 wikiPageWikiLinkText "HES1".
- HES1 wikiPageUsesTemplate Template:Cite_journal.
- HES1 wikiPageUsesTemplate Template:MeshName.
- HES1 wikiPageUsesTemplate Template:NLM_content.
- HES1 wikiPageUsesTemplate Template:PBB.
- HES1 wikiPageUsesTemplate Template:Refbegin.
- HES1 wikiPageUsesTemplate Template:Refend.
- HES1 wikiPageUsesTemplate Template:Reflist.
- HES1 wikiPageUsesTemplate Template:Transcription_factors.
- HES1 subject Category:Transcription_factors.
- HES1 hypernym Protein.
- HES1 type Biomolecule.
- HES1 type Protein.
- HES1 type Factor.
- HES1 type Institute.
- HES1 type Source.
- HES1 type Thing.
- HES1 type Q206229.
- HES1 type Q8054.
- HES1 comment "Transcription factor HES1 (hairy and enhancer of split-1) is a protein that is encoded by the Hes1 gene, and is the mammalian homolog of the hairy gene in Drosophila. HES1 is one of the seven members of the Hes gene family (HES1-7). Hes genes code nuclear proteins that suppress transcription.This protein belongs to the basic helix-loop-helix (bHLH) family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription.".
- HES1 label "HES1".
- HES1 sameAs Q18027301.
- HES1 sameAs m.03gx2mn.
- HES1 sameAs Q18027301.
- HES1 wasDerivedFrom HES1?oldid=640532689.
- HES1 isPrimaryTopicOf HES1.