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- HERG abstract "hERG (the human Ether-à-go-go-Related Gene) is a gene (KCNH2) that codes for a protein known as Kv11.1, the alpha subunit of a potassium ion channel. This ion channel (sometimes simply denoted as 'hERG') is best known for its contribution to the electrical activity of the heart that coordinates the heart's beating (i.e., the hERG channel mediates the repolarizing IKr current in the cardiac action potential). When this channel's ability to conduct electrical current across the cell membrane is inhibited or compromised, either by application of drugs or by rare mutations in some families, it can result in a potentially fatal disorder called long QT syndrome; a number of clinically successful drugs in the market have had the tendency to inhibit hERG, and create a concomitant risk of sudden death, as a side-effect, which has made hERG inhibition an important antitarget that must be avoided during drug development. hERG has also been associated with modulating the functions of some cells of the nervous system and with establishing and maintaining cancer-like features in leukemic cells.".
- HERG entrezgene "3757".
- HERG wikiPageExternalLink fbidq.html?FBgn0000535&resultlist=fbgn26618.data.
- HERG wikiPageExternalLink www.herg.ch.
- HERG wikiPageExternalLink www.ich.org.
- HERG wikiPageExternalLink br.fcgi?book=gene&part=rws.
- HERG wikiPageExternalLink detail.asp?id=1521.
- HERG wikiPageID "1938822".
- HERG wikiPageLength "19008".
- HERG wikiPageOutDegree "39".
- HERG wikiPageRevisionID "699279466".
- HERG wikiPageWikiLink Alpha_helix.
- HERG wikiPageWikiLink Antitarget.
- HERG wikiPageWikiLink Arginine.
- HERG wikiPageWikiLink C-terminus.
- HERG wikiPageWikiLink Cardiac_action_potential.
- HERG wikiPageWikiLink Cardiac_arrhythmia.
- HERG wikiPageWikiLink Cardiac_muscle.
- HERG wikiPageWikiLink Category:Ion_channels.
- HERG wikiPageWikiLink Category:Medicinal_chemistry.
- HERG wikiPageWikiLink Cell_membrane.
- HERG wikiPageWikiLink Channelopathy.
- HERG wikiPageWikiLink City_of_Hope_National_Medical_Center.
- HERG wikiPageWikiLink Crystallography.
- HERG wikiPageWikiLink Diethyl_ether.
- HERG wikiPageWikiLink Drosophila.
- HERG wikiPageWikiLink Duarte,_California.
- HERG wikiPageWikiLink Good_laboratory_practice.
- HERG wikiPageWikiLink Heterologous.
- HERG wikiPageWikiLink KcsA_potassium_channel.
- HERG wikiPageWikiLink Long_QT_syndrome.
- HERG wikiPageWikiLink Lysine.
- HERG wikiPageWikiLink Mutagenesis.
- HERG wikiPageWikiLink N-terminus.
- HERG wikiPageWikiLink PAS_domain.
- HERG wikiPageWikiLink Potassium_channel.
- HERG wikiPageWikiLink Protein_isoform.
- HERG wikiPageWikiLink Protein–protein_interaction.
- HERG wikiPageWikiLink Schizophrenia_Research_Forum.
- HERG wikiPageWikiLink Short_QT_syndrome.
- HERG wikiPageWikiLink Torsades_de_pointes.
- HERG wikiPageWikiLink University_of_Wisconsin–Madison.
- HERG wikiPageWikiLink Voltage-gated_potassium_channel.
- HERG wikiPageWikiLink West_Hollywood,_California.
- HERG wikiPageWikiLink Whisky_a_Go_Go.
- HERG wikiPageWikiLink YWHAE.
- HERG wikiPageWikiLinkText "HERG".
- HERG wikiPageWikiLinkText "hERG Inhibition".
- HERG wikiPageWikiLinkText "hERG".
- HERG wikiPageWikiLinkText "hERG-type".
- HERG wikiPageWikiLinkText "human Ether-à-go-go Related Gene".
- HERG wikiPageWikiLinkText "human ether-a-go-go-related gene".
- HERG wikiPageWikiLinkText "rapid delayed rectifier channels".
- HERG wikiPageWikiLinkText "rapid delayed rectifier".
- HERG wikiPageUsesTemplate Template:Cite_journal.
- HERG wikiPageUsesTemplate Template:Gene.
- HERG wikiPageUsesTemplate Template:Ion_channels.
- HERG wikiPageUsesTemplate Template:Lowercase_title.
- HERG wikiPageUsesTemplate Template:PBB.
- HERG wikiPageUsesTemplate Template:PDB_Gallery.
- HERG wikiPageUsesTemplate Template:Refbegin.
- HERG wikiPageUsesTemplate Template:Refend.
- HERG wikiPageUsesTemplate Template:Reflist.
- HERG subject Category:Ion_channels.
- HERG subject Category:Medicinal_chemistry.
- HERG hypernym Gene.
- HERG type Biomolecule.
- HERG type Protein.
- HERG type Biophysic.
- HERG type Channel.
- HERG type Redirect.
- HERG type Science.
- HERG type Thing.
- HERG type Q206229.
- HERG type Q8054.
- HERG comment "hERG (the human Ether-à-go-go-Related Gene) is a gene (KCNH2) that codes for a protein known as Kv11.1, the alpha subunit of a potassium ion channel. This ion channel (sometimes simply denoted as 'hERG') is best known for its contribution to the electrical activity of the heart that coordinates the heart's beating (i.e., the hERG channel mediates the repolarizing IKr current in the cardiac action potential).".
- HERG label "HERG".
- HERG sameAs Q14865830.
- HERG sameAs قناة-HERG.
- HERG sameAs HERG-Kanal.
- HERG sameAs HERG.
- HERG sameAs m.067jzx.
- HERG sameAs Q14865830.
- HERG sameAs HERG.
- HERG wasDerivedFrom HERG?oldid=699279466.
- HERG isPrimaryTopicOf HERG.