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- HAIR-AN_syndrome abstract "HAIR-AN syndrome consists of hyperandrogenism (HA), insulin resistance (IR), and acanthosis nigricans (AN).Although it is a rare subset of polycystic ovary syndrome, studies on patients with HAIR-AN played a key role in elucidating the pathogenesis of the former. In particular, although HAIR-AN results from two very different types of abnormalities - blocking antibodies against the insulin receptor OR genetically absent/reduced insulin receptor number/function - patients with both types have high levels of androgens (male hormones). Research on the two types of HAIR-AN demonstrated that patients with both forms of HAIR-AN had very high levels of insulin and, critically, that it was the high insulin that caused the elevation in androgens. In other words, regardless of how it comes about, high levels of insulin lead to high levels of androgens. This insight had important implications for the understanding of the more common form of polycystic ovarian syndrome and ultimately led to new treatments for it, such as metformin.".
- HAIR-AN_syndrome wikiPageID "21385384".
- HAIR-AN_syndrome wikiPageLength "2098".
- HAIR-AN_syndrome wikiPageOutDegree "10".
- HAIR-AN_syndrome wikiPageRevisionID "696112332".
- HAIR-AN_syndrome wikiPageWikiLink Acanthosis_nigricans.
- HAIR-AN_syndrome wikiPageWikiLink Androgen.
- HAIR-AN_syndrome wikiPageWikiLink Category:Endocrine-related_cutaneous_conditions.
- HAIR-AN_syndrome wikiPageWikiLink Cutaneous_condition.
- HAIR-AN_syndrome wikiPageWikiLink Hyperandrogenism.
- HAIR-AN_syndrome wikiPageWikiLink Insulin_resistance.
- HAIR-AN_syndrome wikiPageWikiLink List_of_cutaneous_conditions.
- HAIR-AN_syndrome wikiPageWikiLink Metformin.
- HAIR-AN_syndrome wikiPageWikiLink Polycystic_ovary_syndrome.
- HAIR-AN_syndrome wikiPageWikiLink SAHA_syndrome.
- HAIR-AN_syndrome wikiPageWikiLinkText "HAIR-AN syndrome".
- HAIR-AN_syndrome wikiPageUsesTemplate Template:Cutaneous-condition-stub.
- HAIR-AN_syndrome wikiPageUsesTemplate Template:Reflist.
- HAIR-AN_syndrome wikiPageUsesTemplate Template:Rp.
- HAIR-AN_syndrome subject Category:Endocrine-related_cutaneous_conditions.
- HAIR-AN_syndrome type Disease.
- HAIR-AN_syndrome type Redirect.
- HAIR-AN_syndrome type Thing.
- HAIR-AN_syndrome type Q12136.
- HAIR-AN_syndrome comment "HAIR-AN syndrome consists of hyperandrogenism (HA), insulin resistance (IR), and acanthosis nigricans (AN).Although it is a rare subset of polycystic ovary syndrome, studies on patients with HAIR-AN played a key role in elucidating the pathogenesis of the former.".
- HAIR-AN_syndrome label "HAIR-AN syndrome".
- HAIR-AN_syndrome sameAs Q5628903.
- HAIR-AN_syndrome sameAs m.05f8zvp.
- HAIR-AN_syndrome sameAs Q5628903.
- HAIR-AN_syndrome wasDerivedFrom HAIR-AN_syndrome?oldid=696112332.
- HAIR-AN_syndrome isPrimaryTopicOf HAIR-AN_syndrome.