Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/GoLoco_motif> ?p ?o }
Showing triples 1 to 53 of
53
with 100 triples per page.
- GoLoco_motif abstract "GoLoco motif is a protein structural motif.In heterotrimeric G-protein signalling, cell surface receptors (GPCRs) are coupled to membrane-associated heterotrimers comprising a GTP-hydrolyzing subunit G-alpha and a G-beta/G-gamma dimer. The inactive form contains the alpha subunit bound to GDP and complexes with the beta and gamma subunit. When the ligand is associated to the receptor, GDP is displaced from G-alpha and GTP is bound. The GTP/G-alpha complex dissociates from the trimer and associates to an effector until the intrinsic GTPase activity of G-alpha returns the protein to GDP bound form. Reassociation of GDP-bound G-alpha with G-beta/G-gamma dimer terminates the signal. Several mechanisms regulate the signal output at different stage of the G-protein cascade. Two classes of intracellular proteins act as inhibitors of G protein activation: GTPase activating proteins (GAPs), which enhance GTP hydrolysis (see PDOC50132), and guanine dissociation inhibitors (GDIs), which inhibit GDP dissociation. The GoLoco or G-protein regulatory (GPR) motif found in various G-protein regulators. acts as a GDI on G-alpha(i).".
- GoLoco_motif symbol "GoLoco".
- GoLoco_motif thumbnail PDB_1kjy_EBI.jpg?width=300.
- GoLoco_motif wikiPageExternalLink prosite-search-ac?PDOC50132.
- GoLoco_motif wikiPageExternalLink prosite-search-ac?PDOC50238.
- GoLoco_motif wikiPageID "28866317".
- GoLoco_motif wikiPageLength "5496".
- GoLoco_motif wikiPageOutDegree "13".
- GoLoco_motif wikiPageRevisionID "607595045".
- GoLoco_motif wikiPageWikiLink Category:Membrane_proteins.
- GoLoco_motif wikiPageWikiLink GPSM1.
- GoLoco_motif wikiPageWikiLink GPSM2.
- GoLoco_motif wikiPageWikiLink GPSM3.
- GoLoco_motif wikiPageWikiLink G_alpha_subunit.
- GoLoco_motif wikiPageWikiLink G_beta-gamma_complex.
- GoLoco_motif wikiPageWikiLink G_protein–coupled_receptor.
- GoLoco_motif wikiPageWikiLink Heterotrimeric_G_protein.
- GoLoco_motif wikiPageWikiLink PCP2.
- GoLoco_motif wikiPageWikiLink RAP1GAP.
- GoLoco_motif wikiPageWikiLink RGS12.
- GoLoco_motif wikiPageWikiLink RGS14.
- GoLoco_motif wikiPageWikiLink Structural_motif.
- GoLoco_motif wikiPageWikiLinkText "GoLoco motif".
- GoLoco_motif wikiPageWikiLinkText "GoLoco".
- GoLoco_motif caption "crystal structure of human g[alpha]i1 bound to the goloco motif of rgs14".
- GoLoco_motif interpro "IPR003109".
- GoLoco_motif name "GoLoco motif".
- GoLoco_motif pfam "PF02188".
- GoLoco_motif scop "1".
- GoLoco_motif smart "GoLoco".
- GoLoco_motif symbol "GoLoco".
- GoLoco_motif wikiPageUsesTemplate Template:Infobox_protein_family.
- GoLoco_motif wikiPageUsesTemplate Template:InterPro_content.
- GoLoco_motif wikiPageUsesTemplate Template:Membrane-protein-stub.
- GoLoco_motif wikiPageUsesTemplate Template:Reflist.
- GoLoco_motif subject Category:Membrane_proteins.
- GoLoco_motif hypernym Motif.
- GoLoco_motif type Biomolecule.
- GoLoco_motif type Protein.
- GoLoco_motif type Chemical.
- GoLoco_motif type Thing.
- GoLoco_motif type Q206229.
- GoLoco_motif type Q8054.
- GoLoco_motif comment "GoLoco motif is a protein structural motif.In heterotrimeric G-protein signalling, cell surface receptors (GPCRs) are coupled to membrane-associated heterotrimers comprising a GTP-hydrolyzing subunit G-alpha and a G-beta/G-gamma dimer. The inactive form contains the alpha subunit bound to GDP and complexes with the beta and gamma subunit. When the ligand is associated to the receptor, GDP is displaced from G-alpha and GTP is bound.".
- GoLoco_motif label "GoLoco motif".
- GoLoco_motif sameAs Q5574642.
- GoLoco_motif sameAs m.0ddfh5t.
- GoLoco_motif sameAs GoLoco_motiv.
- GoLoco_motif sameAs GoLoco_motiv.
- GoLoco_motif sameAs Q5574642.
- GoLoco_motif wasDerivedFrom GoLoco_motif?oldid=607595045.
- GoLoco_motif depiction PDB_1kjy_EBI.jpg.
- GoLoco_motif isPrimaryTopicOf GoLoco_motif.