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- Glutaredoxin abstract "Glutaredoxins are small redox enzymes of approximately one hundred amino-acid residues that use glutathione as a cofactor. Glutaredoxins are oxidized by substrates, and reduced non-enzymatically by glutathione. In contrast to thioredoxins, which are reduced by thioredoxin reductase, no oxidoreductase exists that specifically reduces glutaredoxins. Instead, glutaredoxins are reduced by the oxidation of glutathione. Oxidized glutathione is then regenerated by glutathione reductase. Together these components compose the glutathione system.Like thioredoxin, which functions in a similar way, glutaredoxin possesses an active centre disulfide bond. It exists in either a reduced or an oxidized form where the two cysteine residues are linked in an intramolecular disulfide bond. Glutaredoxins function as electron carriers in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. Moreover, GRX act in antioxidant defence by reducing dehydroascorbate, peroxiredoxins, and methionine sulfoxide reductase. Beside their function in antioxidant defence, bacterial and plant GRX were shown to bind iron-sulfur clusters and to deliver the cluster to enzymes on demand.".
- Glutaredoxin symbol "Glutaredoxin".
- Glutaredoxin thumbnail PDB_1kte_EBI.jpg?width=300.
- Glutaredoxin wikiPageExternalLink 1.20.4.1.
- Glutaredoxin wikiPageID "9642591".
- Glutaredoxin wikiPageLength "5617".
- Glutaredoxin wikiPageOutDegree "26".
- Glutaredoxin wikiPageRevisionID "706052382".
- Glutaredoxin wikiPageWikiLink Arabidopsis_thaliana.
- Glutaredoxin wikiPageWikiLink Category:Antioxidants.
- Glutaredoxin wikiPageWikiLink Category:EC_1.20.4.
- Glutaredoxin wikiPageWikiLink Category:Protein_domains.
- Glutaredoxin wikiPageWikiLink Category:Single-pass_transmembrane_proteins.
- Glutaredoxin wikiPageWikiLink Dehydroascorbic_acid.
- Glutaredoxin wikiPageWikiLink Deoxyribonucleotide.
- Glutaredoxin wikiPageWikiLink Enterobacteria_phage_T4.
- Glutaredoxin wikiPageWikiLink GLRX.
- Glutaredoxin wikiPageWikiLink GLRX2.
- Glutaredoxin wikiPageWikiLink GLRX3.
- Glutaredoxin wikiPageWikiLink GLRX5.
- Glutaredoxin wikiPageWikiLink Glutathione.
- Glutaredoxin wikiPageWikiLink Glutathione_reductase.
- Glutaredoxin wikiPageWikiLink Iron-sulfur_cluster.
- Glutaredoxin wikiPageWikiLink PTGES2.
- Glutaredoxin wikiPageWikiLink Peroxiredoxin.
- Glutaredoxin wikiPageWikiLink Redox.
- Glutaredoxin wikiPageWikiLink Ribonucleotide_reductase.
- Glutaredoxin wikiPageWikiLink Salicylic_acid.
- Glutaredoxin wikiPageWikiLink Thioredoxin.
- Glutaredoxin wikiPageWikiLink Thioredoxin_reductase.
- Glutaredoxin wikiPageWikiLink Vaccinia.
- Glutaredoxin wikiPageWikiLink Vascular_plant.
- Glutaredoxin wikiPageWikiLink Virus.
- Glutaredoxin wikiPageWikiLinkText "Glutaredoxin".
- Glutaredoxin wikiPageWikiLinkText "glutaredoxin".
- Glutaredoxin cdd "cd02066".
- Glutaredoxin interpro "IPR002109".
- Glutaredoxin name "Glutaredoxin".
- Glutaredoxin opmFamily "139".
- Glutaredoxin opmProtein "32400.0".
- Glutaredoxin pdb "A:17-81 A:250-314 A:69-131 A:69-131 :15-80 A:15-80 :15-80 B:172-230 :4-63 A:4-63 A:4-63 :3-69 :3-69 :3-69 A:3-69 B:2-76 A:2-76 A:2-76 :2-76 A:5-66 A:6-67 A:138-162 :138-162 B:3-61 A:3-61 B:102-152 A:155-181 B:155-181 B:155-181".
- Glutaredoxin pfam "PF00462".
- Glutaredoxin pfamClan "CL0172".
- Glutaredoxin prosite "PDOC00173".
- Glutaredoxin scop "1".
- Glutaredoxin symbol "Glutaredoxin".
- Glutaredoxin wikiPageUsesTemplate Template:1.20-enzyme-stub.
- Glutaredoxin wikiPageUsesTemplate Template:Enzymes.
- Glutaredoxin wikiPageUsesTemplate Template:InterPro.
- Glutaredoxin wikiPageUsesTemplate Template:Membrane-protein-stub.
- Glutaredoxin wikiPageUsesTemplate Template:MeshName.
- Glutaredoxin wikiPageUsesTemplate Template:Other_oxidoreductases.
- Glutaredoxin wikiPageUsesTemplate Template:PDB3.
- Glutaredoxin wikiPageUsesTemplate Template:Pfam_box.
- Glutaredoxin wikiPageUsesTemplate Template:Portal_bar.
- Glutaredoxin wikiPageUsesTemplate Template:Reflist.
- Glutaredoxin subject Category:Antioxidants.
- Glutaredoxin subject Category:EC_1.20.4.
- Glutaredoxin subject Category:Protein_domains.
- Glutaredoxin subject Category:Single-pass_transmembrane_proteins.
- Glutaredoxin hypernym Enzymes.
- Glutaredoxin type Biomolecule.
- Glutaredoxin type Protein.
- Glutaredoxin type Biomolecule.
- Glutaredoxin type Chemical.
- Glutaredoxin type Domain.
- Glutaredoxin type Redirect.
- Glutaredoxin type Thing.
- Glutaredoxin type Q206229.
- Glutaredoxin type Q8054.
- Glutaredoxin comment "Glutaredoxins are small redox enzymes of approximately one hundred amino-acid residues that use glutathione as a cofactor. Glutaredoxins are oxidized by substrates, and reduced non-enzymatically by glutathione. In contrast to thioredoxins, which are reduced by thioredoxin reductase, no oxidoreductase exists that specifically reduces glutaredoxins. Instead, glutaredoxins are reduced by the oxidation of glutathione. Oxidized glutathione is then regenerated by glutathione reductase.".
- Glutaredoxin label "Glutaredoxin".
- Glutaredoxin sameAs Q5572458.
- Glutaredoxin sameAs Glutarredoxina.
- Glutaredoxin sameAs Glutarédoxine.
- Glutaredoxin sameAs Glutarredoxina.
- Glutaredoxin sameAs m.02pmw1f.
- Glutaredoxin sameAs Q5572458.
- Glutaredoxin sameAs 谷氧还蛋白.
- Glutaredoxin wasDerivedFrom Glutaredoxin?oldid=706052382.
- Glutaredoxin depiction PDB_1kte_EBI.jpg.
- Glutaredoxin isPrimaryTopicOf Glutaredoxin.