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- Global_distance_test abstract "The global distance test (GDT), also written as GDT TS to represent \"total score\", is a measure of similarity between two protein structures with identical amino acid sequences but different tertiary structures. It is most commonly used to compare the results of protein structure prediction to the experimentally determined structure as measured by X-ray crystallography or protein NMR. The metric is intended as a more accurate measurement than the more common RMSD metric, which is sensitive to outlier regions created by poor modeling of individual loop regions in a structure that is otherwise reasonably accurate. GDT_TS measurements are used as major assessment criteria in the production of results from the Critical Assessment of Structure Prediction (CASP), a large-scale experiment in the structure prediction community dedicated to assessing current modeling techniques and identifying their primary deficiencies. In general, the higher GDT_TS is, the better a given model is in comparison to reference structure.The GDT score is calculated as the largest set of amino acid residues' alpha carbon atoms in the model structure falling within a defined distance cutoff of their position in the experimental structure. It is typical to calculate the GDT score under several cutoff distances, and scores generally increase with increasing cutoff. A plateau in this increase may indicate an extreme divergence between the experimental and predicted structures, such that no additional atoms are included in any cutoff of a reasonable distance. The high accuracy version of the GDT measure is called GDT-HA. It uses smaller cut off distances (half the size of GDT_TS) and thus is more rigorous.".
- Global_distance_test wikiPageExternalLink LCS_GDT.README.
- Global_distance_test wikiPageExternalLink results.cgi.
- Global_distance_test wikiPageID "7214369".
- Global_distance_test wikiPageLength "3644".
- Global_distance_test wikiPageOutDegree "16".
- Global_distance_test wikiPageRevisionID "703935742".
- Global_distance_test wikiPageWikiLink Alpha_and_beta_carbon.
- Global_distance_test wikiPageWikiLink Amino_acid.
- Global_distance_test wikiPageWikiLink Biomolecular_structure.
- Global_distance_test wikiPageWikiLink CASP.
- Global_distance_test wikiPageWikiLink Category:Bioinformatics.
- Global_distance_test wikiPageWikiLink Category:Computational_chemistry.
- Global_distance_test wikiPageWikiLink Nuclear_magnetic_resonance_spectroscopy_of_proteins.
- Global_distance_test wikiPageWikiLink Outlier.
- Global_distance_test wikiPageWikiLink Peptide_sequence.
- Global_distance_test wikiPageWikiLink Protein_structure.
- Global_distance_test wikiPageWikiLink Protein_structure_prediction.
- Global_distance_test wikiPageWikiLink Root-mean-square_deviation_of_atomic_positions.
- Global_distance_test wikiPageWikiLink Template_modeling_score.
- Global_distance_test wikiPageWikiLink Turn_(biochemistry).
- Global_distance_test wikiPageWikiLink X-ray_crystallography.
- Global_distance_test wikiPageWikiLinkText "GDT (Global Distance Test)".
- Global_distance_test wikiPageWikiLinkText "GDT".
- Global_distance_test wikiPageWikiLinkText "GDT-TS (Global Distance Test — Total Score)".
- Global_distance_test wikiPageWikiLinkText "Global distance test".
- Global_distance_test wikiPageWikiLinkText "global distance test".
- Global_distance_test wikiPageUsesTemplate Template:Reflist.
- Global_distance_test subject Category:Bioinformatics.
- Global_distance_test subject Category:Computational_chemistry.
- Global_distance_test hypernym Measure.
- Global_distance_test type Software.
- Global_distance_test type Biostatistic.
- Global_distance_test comment "The global distance test (GDT), also written as GDT TS to represent \"total score\", is a measure of similarity between two protein structures with identical amino acid sequences but different tertiary structures. It is most commonly used to compare the results of protein structure prediction to the experimentally determined structure as measured by X-ray crystallography or protein NMR.".
- Global_distance_test label "Global distance test".
- Global_distance_test sameAs Q5570829.
- Global_distance_test sameAs m.025wbqb.
- Global_distance_test sameAs Q5570829.
- Global_distance_test wasDerivedFrom Global_distance_test?oldid=703935742.
- Global_distance_test isPrimaryTopicOf Global_distance_test.