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- Gintonin abstract "Gintonin is a glycolipoprotein fraction isolated from ginseng. The non-saponin ingredient was designated as gintonin, where gin was derived from ginseng, ton from the tonic effects of ginseng, and in from protein. The main component of gintonin is a complex of lysophosphatidic acids (LPA) and ginseng proteins such as Ginseng major latex-like protein151 (GLP151) and ginseng ribonuclease-like storage protein.GLP151 is a first plant-derived LPA binding protein as one of Bet v 1 superfamily. GLP151 has a LPA binding domain on H147 and H148 at C-terminal. These two histidine residues bind to phosphate group of LPA and deliver LPA to its cognate receptors to elicit cellular effects such as [Ca2+]i transient and morphological changes.Lysophospholipid receptors are the high affinity and selective target receptor of gintonin. Gintonin induces [Ca2+]i transient in animal cells. Gintonin also shows in vivo anti-Alzheimer's disease through LPA receptor-mediated non-amyloidogenic pathway and boosting of hippocampal cholinergic system and in vivo anti-metastatic effect by inhibition of autotaxin activity.".
- Gintonin thumbnail Gintonin_structure.jpg?width=300.
- Gintonin wikiPageID "34586185".
- Gintonin wikiPageLength "16601".
- Gintonin wikiPageOutDegree "13".
- Gintonin wikiPageRevisionID "696193544".
- Gintonin wikiPageWikiLink Autotaxin.
- Gintonin wikiPageWikiLink Category:Glycolipids.
- Gintonin wikiPageWikiLink Fraction_(chemistry).
- Gintonin wikiPageWikiLink Ginseng.
- Gintonin wikiPageWikiLink Ginsenoside.
- Gintonin wikiPageWikiLink Glycolipoprotein.
- Gintonin wikiPageWikiLink Lysophosphatidic_acid.
- Gintonin wikiPageWikiLink Lysophospholipid_receptor.
- Gintonin wikiPageWikiLink Saponin.
- Gintonin wikiPageWikiLink File:Gintonin_structure.jpg.
- Gintonin wikiPageWikiLinkText "Gintonin".
- Gintonin wikiPageWikiLinkText "gintonin".
- Gintonin wikiPageUsesTemplate Template:Cite_journal.
- Gintonin wikiPageUsesTemplate Template:Reflist.
- Gintonin subject Category:Glycolipids.
- Gintonin hypernym Fraction.
- Gintonin type ChemicalSubstance.
- Gintonin type Lipid.
- Gintonin type Carbohydrate.
- Gintonin type Lipid.
- Gintonin comment "Gintonin is a glycolipoprotein fraction isolated from ginseng. The non-saponin ingredient was designated as gintonin, where gin was derived from ginseng, ton from the tonic effects of ginseng, and in from protein. The main component of gintonin is a complex of lysophosphatidic acids (LPA) and ginseng proteins such as Ginseng major latex-like protein151 (GLP151) and ginseng ribonuclease-like storage protein.GLP151 is a first plant-derived LPA binding protein as one of Bet v 1 superfamily.".
- Gintonin label "Gintonin".
- Gintonin sameAs Q5563294.
- Gintonin sameAs m.0j43wzf.
- Gintonin sameAs Q5563294.
- Gintonin wasDerivedFrom Gintonin?oldid=696193544.
- Gintonin depiction Gintonin_structure.jpg.
- Gintonin isPrimaryTopicOf Gintonin.
