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- Geranylgeranylation abstract "Geranylgeranylation is a form of prenylation, which is a post-translational modification of proteins that involves the attachment of one or two 20-carbon lipophilic geranylgeranyl isoprene units from geranylgeranyl diphosphate to one or two cysteine residue(s) at the C-terminus of specific proteins. Prenylation (including geranylgeranylation) is thought to function, at least in part, as a membrane anchor for proteins.The process of geranylgeranylation can be catalyzed by either geranylgeranyl transferase I (GGTase I) or Rab GGTase (also GGTase II). GGTase I catalyzes the addition of one geranylgeranyl group onto the C-terminal consensus sequence CAAL (somewhat similar to farnesyltransferase reactions), where C=cysteine, A=any aliphatic amino acid, and L=leucine. Rab GGTase adds a total of two geranylgeranyl groups onto two cysteine residues at the C-terminal consensus sequence CXC or XXCC. The source of the geranylgeranyl group is geranylgeranyl diphosphate, which is synthesized by GGPS1 within the isoprenoid biosynthetic pathway.An example of this can be seen in the lipid anchoring of the Rho GTPase family of signaling molecules and the gamma subunit of heterotrimeric G proteins.".
- Geranylgeranylation wikiPageID "10175256".
- Geranylgeranylation wikiPageLength "2073".
- Geranylgeranylation wikiPageOutDegree "17".
- Geranylgeranylation wikiPageRevisionID "695937829".
- Geranylgeranylation wikiPageWikiLink C-terminus.
- Geranylgeranylation wikiPageWikiLink Category:Gene_expression.
- Geranylgeranylation wikiPageWikiLink Category:Molecular_biology.
- Geranylgeranylation wikiPageWikiLink Category:Proteins.
- Geranylgeranylation wikiPageWikiLink Cell_signaling.
- Geranylgeranylation wikiPageWikiLink Cysteine.
- Geranylgeranylation wikiPageWikiLink GGPS1.
- Geranylgeranylation wikiPageWikiLink Geranylgeranyl_pyrophosphate.
- Geranylgeranylation wikiPageWikiLink Geranylgeranyltransferase_type_1.
- Geranylgeranylation wikiPageWikiLink Heterotrimeric_G_protein.
- Geranylgeranylation wikiPageWikiLink Isoprene.
- Geranylgeranylation wikiPageWikiLink Lipid-anchored_protein.
- Geranylgeranylation wikiPageWikiLink Post-translational_modification.
- Geranylgeranylation wikiPageWikiLink Prenylation.
- Geranylgeranylation wikiPageWikiLink Rab_geranylgeranyltransferase.
- Geranylgeranylation wikiPageWikiLink Rho_family_of_GTPases.
- Geranylgeranylation wikiPageWikiLink Terpenoid.
- Geranylgeranylation wikiPageWikiLinkText "Geranylgeranylation".
- Geranylgeranylation wikiPageWikiLinkText "geranylgeranyl".
- Geranylgeranylation wikiPageWikiLinkText "geranylgeranylated".
- Geranylgeranylation wikiPageWikiLinkText "geranylgeranylation".
- Geranylgeranylation wikiPageUsesTemplate Template:Reflist.
- Geranylgeranylation subject Category:Gene_expression.
- Geranylgeranylation subject Category:Molecular_biology.
- Geranylgeranylation subject Category:Proteins.
- Geranylgeranylation hypernym Form.
- Geranylgeranylation type Biomolecule.
- Geranylgeranylation type Biomolecule.
- Geranylgeranylation type Nutrient.
- Geranylgeranylation type Process.
- Geranylgeranylation comment "Geranylgeranylation is a form of prenylation, which is a post-translational modification of proteins that involves the attachment of one or two 20-carbon lipophilic geranylgeranyl isoprene units from geranylgeranyl diphosphate to one or two cysteine residue(s) at the C-terminus of specific proteins.".
- Geranylgeranylation label "Geranylgeranylation".
- Geranylgeranylation sameAs Q5549891.
- Geranylgeranylation sameAs Geranylgeranylierung.
- Geranylgeranylation sameAs m.02q465z.
- Geranylgeranylation sameAs Q5549891.
- Geranylgeranylation wasDerivedFrom Geranylgeranylation?oldid=695937829.
- Geranylgeranylation isPrimaryTopicOf Geranylgeranylation.