Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Genotoxicity> ?p ?o }
- Genotoxicity abstract "In genetics, genotoxicity describes the property of chemical agents that damages the genetic information within a cell causing mutations, which may lead to cancer. While genotoxicity is often confused with mutagenicity, all mutagens are genotoxic, however, not all genotoxic substances are mutagenic. The alteration can have direct or indirect effects on the DNA: the induction of mutations, mistimed event activation, and direct DNA damage leading to mutations. The permanent, heritable changes can affect either somatic cells of the organism or germ cells to be passed on to future generations. Cells prevent expression of the genotoxic mutation by either DNA repair or apoptosis; however, the damage may not always be fixed leading to mutagenesis.To assay for genotoxic molecules, researchers assay for DNA damage in cells exposed to the toxic substrates. This DNA damage can be in the form of single- and double-strand breaks, loss of excision repair, cross-linking, alkali-labile sites, point mutations, and structural and numerical chromosomal aberrations. The compromised integrity of the genetic material has been known to cause cancer. As a consequence, many sophisticated techniques including Ames Assay, in vitro and in vivo Toxicology Tests, and Comet Assay have been developed to assess the chemicals' potential to cause DNA damage that may lead to cancer.".
- Genotoxicity thumbnail Ssvsds.jpg?width=300.
- Genotoxicity wikiPageID "632874".
- Genotoxicity wikiPageLength "18914".
- Genotoxicity wikiPageOutDegree "76".
- Genotoxicity wikiPageRevisionID "702798832".
- Genotoxicity wikiPageWikiLink Adenine.
- Genotoxicity wikiPageWikiLink Alkylation.
- Genotoxicity wikiPageWikiLink Ames_test.
- Genotoxicity wikiPageWikiLink Aneugen.
- Genotoxicity wikiPageWikiLink Apoptosis.
- Genotoxicity wikiPageWikiLink Arsenic.
- Genotoxicity wikiPageWikiLink Bioassay.
- Genotoxicity wikiPageWikiLink Busulfan.
- Genotoxicity wikiPageWikiLink Cancer.
- Genotoxicity wikiPageWikiLink Carcinogen.
- Genotoxicity wikiPageWikiLink Carcinogenesis.
- Genotoxicity wikiPageWikiLink Carmustine.
- Genotoxicity wikiPageWikiLink Category:Carcinogenesis.
- Genotoxicity wikiPageWikiLink Category:Mutation.
- Genotoxicity wikiPageWikiLink Cell_growth.
- Genotoxicity wikiPageWikiLink Chemotherapy_regimen.
- Genotoxicity wikiPageWikiLink Chlormethine.
- Genotoxicity wikiPageWikiLink Chromium.
- Genotoxicity wikiPageWikiLink Chromosomal_fragile_site.
- Genotoxicity wikiPageWikiLink Chromosome.
- Genotoxicity wikiPageWikiLink Chromosome_abnormality.
- Genotoxicity wikiPageWikiLink Clastogen.
- Genotoxicity wikiPageWikiLink Comet_assay.
- Genotoxicity wikiPageWikiLink Comfrey.
- Genotoxicity wikiPageWikiLink Cytotoxicity.
- Genotoxicity wikiPageWikiLink DNA_repair.
- Genotoxicity wikiPageWikiLink Daunorubicin.
- Genotoxicity wikiPageWikiLink Decitabine.
- Genotoxicity wikiPageWikiLink Doxorubicin.
- Genotoxicity wikiPageWikiLink Endothelium.
- Genotoxicity wikiPageWikiLink Enzyme_inhibitor.
- Genotoxicity wikiPageWikiLink Epirubicin.
- Genotoxicity wikiPageWikiLink Etoposide.
- Genotoxicity wikiPageWikiLink Frameshift_mutation.
- Genotoxicity wikiPageWikiLink Genetics.
- Genotoxicity wikiPageWikiLink Germ_cell.
- Genotoxicity wikiPageWikiLink Guanine.
- Genotoxicity wikiPageWikiLink Hepatocyte.
- Genotoxicity wikiPageWikiLink Hydroxyl_radical.
- Genotoxicity wikiPageWikiLink In_vitro.
- Genotoxicity wikiPageWikiLink In_vivo.
- Genotoxicity wikiPageWikiLink Intercalation_(chemistry).
- Genotoxicity wikiPageWikiLink Irinotecan.
- Genotoxicity wikiPageWikiLink Lesion.
- Genotoxicity wikiPageWikiLink Leukemia.
- Genotoxicity wikiPageWikiLink Lymphoma.
- Genotoxicity wikiPageWikiLink Metabolism.
- Genotoxicity wikiPageWikiLink Micronucleus.
- Genotoxicity wikiPageWikiLink Micronucleus_test.
- Genotoxicity wikiPageWikiLink Mutagen.
- Genotoxicity wikiPageWikiLink Mutagenesis.
- Genotoxicity wikiPageWikiLink Mutation.
- Genotoxicity wikiPageWikiLink Oncogene.
- Genotoxicity wikiPageWikiLink Polymorphism_(biology).
- Genotoxicity wikiPageWikiLink Property.
- Genotoxicity wikiPageWikiLink Pyrrolizidine_alkaloid.
- Genotoxicity wikiPageWikiLink Reactive_oxygen_species.
- Genotoxicity wikiPageWikiLink SOS_chromotest.
- Genotoxicity wikiPageWikiLink Somatic_cell.
- Genotoxicity wikiPageWikiLink Spindle_apparatus.
- Genotoxicity wikiPageWikiLink Transversion.
- Genotoxicity wikiPageWikiLink White_blood_cell.
- Genotoxicity wikiPageWikiLink Xenobiotic.
- Genotoxicity wikiPageWikiLink File:Ames_test.svg.
- Genotoxicity wikiPageWikiLink File:Genotoxic_Damage.png.
- Genotoxicity wikiPageWikiLink File:Normal_cancer_cell_division_from_NIH-2.svg.
- Genotoxicity wikiPageWikiLink File:Ssvsds.jpg.
- Genotoxicity wikiPageWikiLink File:Transitions_and_transversions.svg.
- Genotoxicity wikiPageWikiLinkText "DNA damaging chemicals".
- Genotoxicity wikiPageWikiLinkText "Genotoxicity of metal ions: chemical insights".
- Genotoxicity wikiPageWikiLinkText "Genotoxicity".
- Genotoxicity wikiPageWikiLinkText "damage DNA".
- Genotoxicity wikiPageWikiLinkText "genotoxic agents".
- Genotoxicity wikiPageWikiLinkText "genotoxic substances".
- Genotoxicity wikiPageWikiLinkText "genotoxic".
- Genotoxicity wikiPageWikiLinkText "genotoxicity".
- Genotoxicity wikiPageUsesTemplate Template:Cite_book.
- Genotoxicity wikiPageUsesTemplate Template:Cite_journal.
- Genotoxicity wikiPageUsesTemplate Template:Genotoxicity.
- Genotoxicity wikiPageUsesTemplate Template:Refbegin.
- Genotoxicity wikiPageUsesTemplate Template:Refend.
- Genotoxicity wikiPageUsesTemplate Template:Reflist.
- Genotoxicity wikiPageUsesTemplate Template:See_also.
- Genotoxicity subject Category:Carcinogenesis.
- Genotoxicity subject Category:Mutation.
- Genotoxicity type Thing.
- Genotoxicity comment "In genetics, genotoxicity describes the property of chemical agents that damages the genetic information within a cell causing mutations, which may lead to cancer. While genotoxicity is often confused with mutagenicity, all mutagens are genotoxic, however, not all genotoxic substances are mutagenic. The alteration can have direct or indirect effects on the DNA: the induction of mutations, mistimed event activation, and direct DNA damage leading to mutations.".
- Genotoxicity label "Genotoxicity".
- Genotoxicity seeAlso Ames_test.
- Genotoxicity seeAlso Comet_assay.
- Genotoxicity sameAs Q1009245.
- Genotoxicity sameAs سمية_جينية.
- Genotoxicity sameAs Genotoxicitat.
- Genotoxicity sameAs Genotoxizität.