DBpedia – Linked Data Fragments

Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Gene_regulatory_network> ?p ?o }

• Gene_regulatory_network abstract "A gene regulatory network or genetic regulatory network (GRN) is a collection of regulators thatinteract with each other and with other substances in the cell to govern the gene expression levels of mRNA and proteins.The regulator can be DNA, RNA, protein and their complex. The interaction can be direct or indirect (through their transcribed RNA or translated protein).In general, each mRNA molecule goes on to make a specific protein (or set of proteins). In some cases this protein will be structural, and will accumulate at the cell membrane or within the cell to give it particular structural properties. In other cases the protein will be an enzyme, i.e., a micro-machine that catalyses a certain reaction, such as the breakdown of a food source or toxin. Some proteins though serve only to activate other genes, and these are the transcription factors that are the main players in regulatory networks or cascades. By binding to the promoter region at the start of other genes they turn them on, initiating the production of another protein, and so on. Some transcription factors are inhibitory.In single-celled organisms, regulatory networks respond to the external environment, optimising the cell at a given time for survival in this environment. Thus a yeast cell, finding itself in a sugar solution, will turn on genes to make enzymes that process the sugar to alcohol. This process, which we associate with wine-making, is how the yeast cell makes its living, gaining energy to multiply, which under normal circumstances would enhance its survival prospects.In multicellular animals the same principle has been put in the service of gene cascades that control body-shape. Each time a cell divides, two cells result which, although they contain the same genome in full, can differ in which genes are turned on and making proteins. Sometimes a 'self-sustaining feedback loop' ensures that a cell maintains its identity and passes it on. Less understood is the mechanism of epigenetics by which chromatin modification may provide cellular memory by blocking or allowing transcription. A major feature of multicellular animals is the use of morphogen gradients, which in effect provide a positioning system that tells a cell where in the body it is, and hence what sort of cell to become. A gene that is turned on in one cell may make a product that leaves the cell and diffuses through adjacent cells, entering them and turning on genes only when it is present above a certain threshold level. These cells are thus induced into a new fate, and may even generate other morphogens that signal back to the original cell. Over longer distances morphogens may use the active process of signal transduction. Such signalling controls embryogenesis, the building of a body plan from scratch through a series of sequential steps. They also control and maintain adult bodies through feedback processes, and the loss of such feedback because of a mutation can be responsible for the cell proliferation that is seen in cancer. In parallel with this process of building structure, the gene cascade turns on genes that make structural proteins that give each cell the physical properties it needs.It has been suggested that, because biological molecular interactions are intrinsically stochastic, gene networks are the result of cellular processes and not their cause (i.e. cellular Darwinism). However, recent experimental evidence has favored the attractor view of cell fates.".
• Gene_regulatory_network thumbnail Gene_Regulatory_Network.jpg?width=300.
• Gene_regulatory_network wikiPageExternalLink abl.
• Gene_regulatory_network wikiPageExternalLink crn.vistainformatics.com.
• Gene_regulatory_network wikiPageExternalLink biorel.
• Gene_regulatory_network wikiPageExternalLink GRNclocks.
• Gene_regulatory_network wikiPageExternalLink ICSBtut.
• Gene_regulatory_network wikiPageExternalLink bio.
• Gene_regulatory_network wikiPageExternalLink ggm.html.
• Gene_regulatory_network wikiPageExternalLink www.genenetwork.org.
• Gene_regulatory_network wikiPageExternalLink network-bib.pdf.
• Gene_regulatory_network wikiPageExternalLink cellcyle_addmaterial.
• Gene_regulatory_network wikiPageID "356382".
• Gene_regulatory_network wikiPageLength "44210".
• Gene_regulatory_network wikiPageOutDegree "99".
• Gene_regulatory_network wikiPageRevisionID "705799115".
• Gene_regulatory_network wikiPageWikiLink Adaptation.
• Gene_regulatory_network wikiPageWikiLink Ansatz.
• Gene_regulatory_network wikiPageWikiLink Artificial_neural_network.
• Gene_regulatory_network wikiPageWikiLink Attractor.
• Gene_regulatory_network wikiPageWikiLink Bacteria.
• Gene_regulatory_network wikiPageWikiLink Bayesian_network.
• Gene_regulatory_network wikiPageWikiLink Bifurcation_theory.
• Gene_regulatory_network wikiPageWikiLink Body_plan.
• Gene_regulatory_network wikiPageWikiLink Boolean_function.
• Gene_regulatory_network wikiPageWikiLink Boolean_network.
• Gene_regulatory_network wikiPageWikiLink Caenorhabditis.
• Gene_regulatory_network wikiPageWikiLink Cancer.
• Gene_regulatory_network wikiPageWikiLink Category:Gene_expression.
• Gene_regulatory_network wikiPageWikiLink Category:Networks.
• Gene_regulatory_network wikiPageWikiLink Category:Systems_biology.
• Gene_regulatory_network wikiPageWikiLink Cellular_differentiation.
• Gene_regulatory_network wikiPageWikiLink Chaos_theory.
• Gene_regulatory_network wikiPageWikiLink Chromatin.
• Gene_regulatory_network wikiPageWikiLink Cis-regulatory_module.
• Gene_regulatory_network wikiPageWikiLink Convergent_evolution.
• Gene_regulatory_network wikiPageWikiLink Critical_point_(mathematics).
• Gene_regulatory_network wikiPageWikiLink DNA.
• Gene_regulatory_network wikiPageWikiLink Differential_equation.
• Gene_regulatory_network wikiPageWikiLink Diffusion.
• Gene_regulatory_network wikiPageWikiLink Directed_graph.
• Gene_regulatory_network wikiPageWikiLink Drosophila.
• Gene_regulatory_network wikiPageWikiLink Dynamical_system.
• Gene_regulatory_network wikiPageWikiLink Embryogenesis.
• Gene_regulatory_network wikiPageWikiLink Enzyme.
• Gene_regulatory_network wikiPageWikiLink Epigenesis_(biology).
• Gene_regulatory_network wikiPageWikiLink Epigenetics.
• Gene_regulatory_network wikiPageWikiLink Feedback.
• Gene_regulatory_network wikiPageWikiLink File:Feed-forward_motif.GIF.
• Gene_regulatory_network wikiPageWikiLink Fixed_point_(mathematics).
• Gene_regulatory_network wikiPageWikiLink Gene.
• Gene_regulatory_network wikiPageWikiLink GeneNetwork.
• Gene_regulatory_network wikiPageWikiLink Gene_duplication.
• Gene_regulatory_network wikiPageWikiLink Gene_expression.
• Gene_regulatory_network wikiPageWikiLink Gillespie_algorithm.
• Gene_regulatory_network wikiPageWikiLink Graphical_Gaussian_model.
• Gene_regulatory_network wikiPageWikiLink Hill_equation_(biochemistry).
• Gene_regulatory_network wikiPageWikiLink Hippo_signaling_pathway.
• Gene_regulatory_network wikiPageWikiLink Information_processing.
• Gene_regulatory_network wikiPageWikiLink James_Collins_(bioengineer).
• Gene_regulatory_network wikiPageWikiLink Journal_of_Theoretical_Biology.
• Gene_regulatory_network wikiPageWikiLink Mathematical_model.
• Gene_regulatory_network wikiPageWikiLink Messenger_RNA.
• Gene_regulatory_network wikiPageWikiLink Michaelis–Menten_kinetics.
• Gene_regulatory_network wikiPageWikiLink Modularity_(biology).
• Gene_regulatory_network wikiPageWikiLink Morphogen.
• Gene_regulatory_network wikiPageWikiLink Morphogenesis.
• Gene_regulatory_network wikiPageWikiLink Network_motif.
• Gene_regulatory_network wikiPageWikiLink Network_topology.
• Gene_regulatory_network wikiPageWikiLink Nonlinear_system.
• Gene_regulatory_network wikiPageWikiLink Operon.
• Gene_regulatory_network wikiPageWikiLink Ordinary_differential_equation.
• Gene_regulatory_network wikiPageWikiLink Oscillation.
• Gene_regulatory_network wikiPageWikiLink Petri_net.
• Gene_regulatory_network wikiPageWikiLink Pleiotropy.
• Gene_regulatory_network wikiPageWikiLink Polynomial.
• Gene_regulatory_network wikiPageWikiLink Preferential_attachment.
• Gene_regulatory_network wikiPageWikiLink Process_calculus.
• Gene_regulatory_network wikiPageWikiLink Promoter_(genetics).
• Gene_regulatory_network wikiPageWikiLink Protein.
• Gene_regulatory_network wikiPageWikiLink RNA.
• Gene_regulatory_network wikiPageWikiLink Rate_equation.
• Gene_regulatory_network wikiPageWikiLink Reaction_rate.
• Gene_regulatory_network wikiPageWikiLink Recurrent_neural_network.
• Gene_regulatory_network wikiPageWikiLink Scale-free_network.
• Gene_regulatory_network wikiPageWikiLink Signal_transduction.
• Gene_regulatory_network wikiPageWikiLink Stability_theory.
• Gene_regulatory_network wikiPageWikiLink Steady_state.
• Gene_regulatory_network wikiPageWikiLink Steady_state_(biochemistry).
• Gene_regulatory_network wikiPageWikiLink Stochastic.
• Gene_regulatory_network wikiPageWikiLink Stochastic_differential_equation.
• Gene_regulatory_network wikiPageWikiLink Stuart_Kauffman.
• Gene_regulatory_network wikiPageWikiLink Synexpression.
• Gene_regulatory_network wikiPageWikiLink Systems_biology.
• Gene_regulatory_network wikiPageWikiLink Time_series.
• Gene_regulatory_network wikiPageWikiLink Transcription_factor.
• Gene_regulatory_network wikiPageWikiLink Vertex_(graph_theory).
• Gene_regulatory_network wikiPageWikiLink Weighted_correlation_network_analysis.
• Gene_regulatory_network wikiPageWikiLink Xenopus.
• Gene_regulatory_network wikiPageWikiLink File:DG_Network_in_Hybrid_Rice.png.

• next