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- Gastrin-releasing_peptide_receptor abstract "The gastrin-releasing peptide receptor (GRPR), now properly known as BB2 is a G protein-coupled receptor whose endogenous ligand is gastrin releasing peptide. In humans it is highly expressed in the pancreas and is also expressed in the stomach, adrenal cortex and brain.Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.The transcription factor CREB is a regulator of human GRP-R expression in colon cancer.".
- Gastrin-releasing_peptide_receptor entrezgene "2925".
- Gastrin-releasing_peptide_receptor wikiPageExternalLink ReceptorDisplayForward?receptorID=2957.
- Gastrin-releasing_peptide_receptor wikiPageID "12910855".
- Gastrin-releasing_peptide_receptor wikiPageLength "10612".
- Gastrin-releasing_peptide_receptor wikiPageOutDegree "12".
- Gastrin-releasing_peptide_receptor wikiPageRevisionID "678831549".
- Gastrin-releasing_peptide_receptor wikiPageWikiLink Adrenal_cortex.
- Gastrin-releasing_peptide_receptor wikiPageWikiLink Brain.
- Gastrin-releasing_peptide_receptor wikiPageWikiLink CREB.
- Gastrin-releasing_peptide_receptor wikiPageWikiLink Category:G_protein_coupled_receptors.
- Gastrin-releasing_peptide_receptor wikiPageWikiLink Colorectal_cancer.
- Gastrin-releasing_peptide_receptor wikiPageWikiLink Endogeny_(biology).
- Gastrin-releasing_peptide_receptor wikiPageWikiLink G_protein–coupled_receptor.
- Gastrin-releasing_peptide_receptor wikiPageWikiLink Gastrin-releasing_peptide.
- Gastrin-releasing_peptide_receptor wikiPageWikiLink Pancreas.
- Gastrin-releasing_peptide_receptor wikiPageWikiLink Regulation_of_gene_expression.
- Gastrin-releasing_peptide_receptor wikiPageWikiLink Stomach.
- Gastrin-releasing_peptide_receptor wikiPageWikiLink Transcription_factor.
- Gastrin-releasing_peptide_receptor wikiPageWikiLinkText "Gastrin-releasing peptide receptor".
- Gastrin-releasing_peptide_receptor wikiPageWikiLinkText "gastrin-releasing peptide receptor".
- Gastrin-releasing_peptide_receptor requireManualInspection "no".
- Gastrin-releasing_peptide_receptor summaryText "Gastrin-releasing peptide regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.".
- Gastrin-releasing_peptide_receptor updateCitations "yes".
- Gastrin-releasing_peptide_receptor updatePage "yes".
- Gastrin-releasing_peptide_receptor updateProteinBox "yes".
- Gastrin-releasing_peptide_receptor updateSummary "yes".
- Gastrin-releasing_peptide_receptor wikiPageUsesTemplate Template:Cite_journal.
- Gastrin-releasing_peptide_receptor wikiPageUsesTemplate Template:Cite_web.
- Gastrin-releasing_peptide_receptor wikiPageUsesTemplate Template:G_protein-coupled_receptors.
- Gastrin-releasing_peptide_receptor wikiPageUsesTemplate Template:MeshName.
- Gastrin-releasing_peptide_receptor wikiPageUsesTemplate Template:NLM_content.
- Gastrin-releasing_peptide_receptor wikiPageUsesTemplate Template:PBB.
- Gastrin-releasing_peptide_receptor wikiPageUsesTemplate Template:PBB_Controls.
- Gastrin-releasing_peptide_receptor wikiPageUsesTemplate Template:PBB_Further_reading.
- Gastrin-releasing_peptide_receptor wikiPageUsesTemplate Template:PBB_Summary.
- Gastrin-releasing_peptide_receptor wikiPageUsesTemplate Template:Refbegin.
- Gastrin-releasing_peptide_receptor wikiPageUsesTemplate Template:Refend.
- Gastrin-releasing_peptide_receptor wikiPageUsesTemplate Template:Reflist.
- Gastrin-releasing_peptide_receptor wikiPageUsesTemplate Template:Transmembranereceptor-stub.
- Gastrin-releasing_peptide_receptor subject Category:G_protein_coupled_receptors.
- Gastrin-releasing_peptide_receptor hypernym Receptor.
- Gastrin-releasing_peptide_receptor type Biomolecule.
- Gastrin-releasing_peptide_receptor type Protein.
- Gastrin-releasing_peptide_receptor type Institute.
- Gastrin-releasing_peptide_receptor type Source.
- Gastrin-releasing_peptide_receptor type Thing.
- Gastrin-releasing_peptide_receptor type Q206229.
- Gastrin-releasing_peptide_receptor type Q8054.
- Gastrin-releasing_peptide_receptor comment "The gastrin-releasing peptide receptor (GRPR), now properly known as BB2 is a G protein-coupled receptor whose endogenous ligand is gastrin releasing peptide.".
- Gastrin-releasing_peptide_receptor label "Gastrin-releasing peptide receptor".
- Gastrin-releasing_peptide_receptor sameAs Q15318423.
- Gastrin-releasing_peptide_receptor sameAs m.02xckyv.
- Gastrin-releasing_peptide_receptor sameAs Gastrin-oslobađajući_peptidni_receptor.
- Gastrin-releasing_peptide_receptor sameAs Gastrin-oslobađajući_peptidni_receptor.
- Gastrin-releasing_peptide_receptor sameAs Q15318423.
- Gastrin-releasing_peptide_receptor wasDerivedFrom Gastrin-releasing_peptide_receptor?oldid=678831549.
- Gastrin-releasing_peptide_receptor isPrimaryTopicOf Gastrin-releasing_peptide_receptor.