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- Gab_operon abstract "The gab operon is responsible for the conversion of γ-aminobutyrate (GABA) to succinate. The gab operon comprises three structural genes – gabD, gabT and gabP – that encode for a succinate semialdehyde dehydrogenase, GABA transaminase and a GABA permease respectively. There is a regulatory gene csiR, downstream of the operon, that codes for a putative transcriptional repressor and is activated when nitrogen is limiting.The gab operon has been characterized in Escherichia coli and significant homologies for the enzymes have been found in organisms such as Saccharomyces cerevisiae, rats and humans.Limited nitrogen conditions activate the gab genes. The enzymes produced by these genes convert GABA to succinate, which then enters the TCA cycle, to be used as a source of energy. The gab operon is also known to contribute to polyamine homeostasis during nitrogen-limited growth and to maintain high internal glutamate concentrations under stress conditions.".
- Gab_operon thumbnail Gab_reaction.jpg?width=300.
- Gab_operon wikiPageID "37242178".
- Gab_operon wikiPageLength "6983".
- Gab_operon wikiPageOutDegree "16".
- Gab_operon wikiPageRevisionID "648647363".
- Gab_operon wikiPageWikiLink 4-aminobutyrate_transaminase.
- Gab_operon wikiPageWikiLink CAMP_receptor_protein.
- Gab_operon wikiPageWikiLink Category:Gene_expression.
- Gab_operon wikiPageWikiLink Citric_acid_cycle.
- Gab_operon wikiPageWikiLink Gamma-Aminobutyric_acid.
- Gab_operon wikiPageWikiLink Glutamic_acid.
- Gab_operon wikiPageWikiLink Neurotransmitter.
- Gab_operon wikiPageWikiLink Operon.
- Gab_operon wikiPageWikiLink Polyamine.
- Gab_operon wikiPageWikiLink Putrescine.
- Gab_operon wikiPageWikiLink RpoS.
- Gab_operon wikiPageWikiLink Succinate-semialdehyde_dehydrogenase.
- Gab_operon wikiPageWikiLink Succinic_acid.
- Gab_operon wikiPageWikiLink File:Gab_reaction.jpg.
- Gab_operon wikiPageWikiLink File:Structure_and_regulation_of_the_gab_Operon.jpg.
- Gab_operon wikiPageWikiLinkText "gab operon".
- Gab_operon wikiPageUsesTemplate Template:Reflist.
- Gab_operon wikiPageUsesTemplate Template:Unreferencedsection.
- Gab_operon subject Category:Gene_expression.
- Gab_operon type Process.
- Gab_operon comment "The gab operon is responsible for the conversion of γ-aminobutyrate (GABA) to succinate. The gab operon comprises three structural genes – gabD, gabT and gabP – that encode for a succinate semialdehyde dehydrogenase, GABA transaminase and a GABA permease respectively.".
- Gab_operon label "Gab operon".
- Gab_operon sameAs Q5515236.
- Gab_operon sameAs m.0n5t__x.
- Gab_operon sameAs ГАМК-оперон.
- Gab_operon sameAs Q5515236.
- Gab_operon wasDerivedFrom Gab_operon?oldid=648647363.
- Gab_operon depiction Gab_reaction.jpg.
- Gab_operon isPrimaryTopicOf Gab_operon.