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- GDF11 abstract "Growth differentiation factor 11 (GDF11) also known as bone morphogenetic protein 11 (BMP-11) is a protein that in humans is encoded by the GDF11 gene.It acts as a cytokine. The BMP group of proteins is characterized by a polybasic proteolytic processing site, which is cleaved to produce a protein containing seven conserved cysteine residues. GDF11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development.In 2014, GDF11 was described as an anti-aging factor in two publications based on the results of a parabiosis experiments with mice that were chosen as Science's scientific breakthrough of the year. Later studies questioned these findings. Researchers disagree on the selectivity of the tests used to measure GDF11 and on the activity of GDF11 from various commercially-available sources. The full relationship of GDF11 to aging—and any possible differences in the action of GDF11 in mice, rats, and humans—is unclear and continues to be researched.".
- GDF11 entrezgene "10220".
- GDF11 wikiPageID "10267706".
- GDF11 wikiPageLength "17730".
- GDF11 wikiPageOutDegree "35".
- GDF11 wikiPageRevisionID "706605691".
- GDF11 wikiPageWikiLink ACVR1B.
- GDF11 wikiPageWikiLink ACVR1C.
- GDF11 wikiPageWikiLink Anatomical_terms_of_location.
- GDF11 wikiPageWikiLink Atrial_natriuretic_peptide.
- GDF11 wikiPageWikiLink Brain_natriuretic_peptide.
- GDF11 wikiPageWikiLink Cardiac_muscle_cell.
- GDF11 wikiPageWikiLink Category:Aging-related_proteins.
- GDF11 wikiPageWikiLink Category:Developmental_genes_and_proteins.
- GDF11 wikiPageWikiLink Category:TGFβ_domain.
- GDF11 wikiPageWikiLink Cell_cycle.
- GDF11 wikiPageWikiLink Cytokine.
- GDF11 wikiPageWikiLink FOX_proteins.
- GDF11 wikiPageWikiLink Ganglion.
- GDF11 wikiPageWikiLink Gene.
- GDF11 wikiPageWikiLink Hematopoietic_stem_cell.
- GDF11 wikiPageWikiLink Hox_gene.
- GDF11 wikiPageWikiLink Myostatin.
- GDF11 wikiPageWikiLink Neural_plate.
- GDF11 wikiPageWikiLink Olfactory_epithelium.
- GDF11 wikiPageWikiLink Olfactory_receptor.
- GDF11 wikiPageWikiLink Parabiosis.
- GDF11 wikiPageWikiLink Progenitor_cell.
- GDF11 wikiPageWikiLink Protein.
- GDF11 wikiPageWikiLink Retina.
- GDF11 wikiPageWikiLink SERCA.
- GDF11 wikiPageWikiLink Skeletal_muscle.
- GDF11 wikiPageWikiLink Spinal_cord.
- GDF11 wikiPageWikiLink Stem_cell.
- GDF11 wikiPageWikiLink TGF_beta_receptor_1.
- GDF11 wikiPageWikiLink Transforming_growth_factor_beta_superfamily.
- GDF11 wikiPageWikiLink WFIKKN2.
- GDF11 wikiPageWikiLinkText "GDF11".
- GDF11 wikiPageUsesTemplate Template:Cite_journal.
- GDF11 wikiPageUsesTemplate Template:Clear.
- GDF11 wikiPageUsesTemplate Template:PBB.
- GDF11 wikiPageUsesTemplate Template:Refbegin.
- GDF11 wikiPageUsesTemplate Template:Refend.
- GDF11 wikiPageUsesTemplate Template:Reflist.
- GDF11 wikiPageUsesTemplate Template:TGF_beta_signaling.
- GDF11 wikiPageUsesTemplate Template:UCSC_gene_details.
- GDF11 wikiPageUsesTemplate Template:UCSC_genome_browser.
- GDF11 subject Category:Aging-related_proteins.
- GDF11 subject Category:Developmental_genes_and_proteins.
- GDF11 subject Category:TGFβ_domain.
- GDF11 hypernym Protein.
- GDF11 type Biomolecule.
- GDF11 type Protein.
- GDF11 type Thing.
- GDF11 type Q206229.
- GDF11 type Q8054.
- GDF11 comment "Growth differentiation factor 11 (GDF11) also known as bone morphogenetic protein 11 (BMP-11) is a protein that in humans is encoded by the GDF11 gene.It acts as a cytokine. The BMP group of proteins is characterized by a polybasic proteolytic processing site, which is cleaved to produce a protein containing seven conserved cysteine residues. GDF11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth.".
- GDF11 label "GDF11".
- GDF11 sameAs Q14912147.
- GDF11 sameAs GDF11.
- GDF11 sameAs m.02q6_jb.
- GDF11 sameAs Q14912147.
- GDF11 wasDerivedFrom GDF11?oldid=706605691.
- GDF11 isPrimaryTopicOf GDF11.