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- GAB2 abstract "GRB2-associated-binding protein 2 also known as GAB2 is a protein that in humans is encoded by the GAB2 gene.GAB2 is a docking protein with a conserved, folded PH domain attached to the membrane and a large disordered region, which hosts interactions with signaling molecules. It is a member of the GAB/DOS family localized on the internal membrane of the cell. It mediates the interaction between receptor tyrosine kinases (RTKs) and non-RTK receptors serving as the gateway into the cell for activation of SHP2, Phosphatidylinositol 3-kinase (PI3K), Grb2, ERK, and AKT and acting as one of the first steps in these signaling pathways. GAB2 has been shown to be important in physiological functions such as growth in bone marrow and cardiac function. GAB2 has also been associated with many diseases including leukemia and Alzheimer's disease.".
- GAB2 entrezgene "9846".
- GAB2 wikiPageExternalLink 6731227.stm.
- GAB2 wikiPageID "11677095".
- GAB2 wikiPageLength "24708".
- GAB2 wikiPageOutDegree "82".
- GAB2 wikiPageRevisionID "674196654".
- GAB2 wikiPageWikiLink Adapter_molecule_crk.
- GAB2 wikiPageWikiLink Alzheimers_disease.
- GAB2 wikiPageWikiLink Amyloid.
- GAB2 wikiPageWikiLink Amyloid_precursor_protein.
- GAB2 wikiPageWikiLink Anaphylaxis.
- GAB2 wikiPageWikiLink Angiopoietin.
- GAB2 wikiPageWikiLink Apolipoprotein_E.
- GAB2 wikiPageWikiLink Assay.
- GAB2 wikiPageWikiLink Biochemistry_of_Alzheimers_disease.
- GAB2 wikiPageWikiLink C-Jun_N-terminal_kinases.
- GAB2 wikiPageWikiLink CRKL.
- GAB2 wikiPageWikiLink Category:Alzheimers_disease.
- GAB2 wikiPageWikiLink Category:Molecular_neuroscience.
- GAB2 wikiPageWikiLink Category:Proteins.
- GAB2 wikiPageWikiLink Complementary_DNA.
- GAB2 wikiPageWikiLink Cytokine_receptor.
- GAB2 wikiPageWikiLink Epidermal_growth_factor.
- GAB2 wikiPageWikiLink Erythropoietin.
- GAB2 wikiPageWikiLink Extracellular_signal-regulated_kinases.
- GAB2 wikiPageWikiLink Fc_receptor.
- GAB2 wikiPageWikiLink GAB1.
- GAB2 wikiPageWikiLink GRB2.
- GAB2 wikiPageWikiLink GSK-3.
- GAB2 wikiPageWikiLink Gene.
- GAB2 wikiPageWikiLink Growth_hormone.
- GAB2 wikiPageWikiLink Homology_(biology).
- GAB2 wikiPageWikiLink Immunoprecipitation.
- GAB2 wikiPageWikiLink Insulin.
- GAB2 wikiPageWikiLink Integrin.
- GAB2 wikiPageWikiLink Intrinsically_disordered_proteins.
- GAB2 wikiPageWikiLink Juvenile_myelomonocytic_leukemia.
- GAB2 wikiPageWikiLink Leukemia.
- GAB2 wikiPageWikiLink Microglia.
- GAB2 wikiPageWikiLink Mitogen-activated_protein_kinase.
- GAB2 wikiPageWikiLink Mutagenesis.
- GAB2 wikiPageWikiLink Neurofibrillary_tangle.
- GAB2 wikiPageWikiLink Non-receptor_tyrosine_kinase.
- GAB2 wikiPageWikiLink Osteopetrosis.
- GAB2 wikiPageWikiLink PLCG2.
- GAB2 wikiPageWikiLink PTPN11.
- GAB2 wikiPageWikiLink Philadelphia_chromosome.
- GAB2 wikiPageWikiLink Phosphatidylinositol_(3,4,5)-trisphosphate.
- GAB2 wikiPageWikiLink Phosphoinositide_3-kinase.
- GAB2 wikiPageWikiLink Pleckstrin_homology_domain.
- GAB2 wikiPageWikiLink Protein.
- GAB2 wikiPageWikiLink Protein_kinase_B.
- GAB2 wikiPageWikiLink Protein_secondary_structure.
- GAB2 wikiPageWikiLink Protein–protein_interaction.
- GAB2 wikiPageWikiLink RICS_(gene).
- GAB2 wikiPageWikiLink Rac_(GTPase).
- GAB2 wikiPageWikiLink Ras_subfamily.
- GAB2 wikiPageWikiLink Receptor_tyrosine_kinase.
- GAB2 wikiPageWikiLink Red_blood_cell.
- GAB2 wikiPageWikiLink SH2_domain.
- GAB2 wikiPageWikiLink SH3_domain.
- GAB2 wikiPageWikiLink SHC1.
- GAB2 wikiPageWikiLink Short_linear_motif.
- GAB2 wikiPageWikiLink Tau_protein.
- GAB2 wikiPageWikiLink Western_blot.
- GAB2 wikiPageWikiLinkText "GAB2".
- GAB2 wikiPageUsesTemplate Template:Cite_journal.
- GAB2 wikiPageUsesTemplate Template:PBB.
- GAB2 wikiPageUsesTemplate Template:Refbegin.
- GAB2 wikiPageUsesTemplate Template:Refend.
- GAB2 wikiPageUsesTemplate Template:Reflist.
- GAB2 wikiPageUsesTemplate Template:Use_dmy_dates.
- GAB2 subject Category:Alzheimers_disease.
- GAB2 subject Category:Molecular_neuroscience.
- GAB2 subject Category:Proteins.
- GAB2 hypernym Protein.
- GAB2 type Biomolecule.
- GAB2 type Protein.
- GAB2 type Biomolecule.
- GAB2 type Disorder.
- GAB2 type Nutrient.
- GAB2 type Thing.
- GAB2 type Q206229.
- GAB2 type Q8054.
- GAB2 comment "GRB2-associated-binding protein 2 also known as GAB2 is a protein that in humans is encoded by the GAB2 gene.GAB2 is a docking protein with a conserved, folded PH domain attached to the membrane and a large disordered region, which hosts interactions with signaling molecules. It is a member of the GAB/DOS family localized on the internal membrane of the cell.".
- GAB2 label "GAB2".
- GAB2 sameAs Q14914401.
- GAB2 sameAs m.02rnlwq.
- GAB2 sameAs GAB2.
- GAB2 sameAs Q14914401.
- GAB2 wasDerivedFrom GAB2?oldid=674196654.
- GAB2 isPrimaryTopicOf GAB2.