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- Fluorinase abstract "The fluorinase enzyme (EC 2.5.1.63, also known as adenosyl-fluoride synthase) catalyzes the reaction between fluoride ion and the co-factor S-adenosyl-L-methionine to generate L-methionine and 5'-fluoro-5'-deoxyadenosine, the first committed product of the fluorometabolite biosynthesis pathway. The fluorinase was originally isolated from the soil bacterium Streptomyces cattleya, but homologues have since been identified in a number of other bacterial species, including Streptomyces sp. MA37, Nocardia brasiliensis and Actinoplanes sp. N902-109. This is the only known enzyme capable of catalysing the formation of a carbon-fluorine bond, the strongest single bond in organic chemistry.A homologous chlorinase enzyme, which catalyses the same reaction with chloride rather than fluoride ion, has been isolated from Salinospora tropica, from the biosynthetic pathway of salinosporamide A.".
- Fluorinase ecNumber "2.5.1.63".
- Fluorinase thumbnail Fluorinase_crystal_structure.png?width=300.
- Fluorinase wikiPageID "17180844".
- Fluorinase wikiPageLength "11866".
- Fluorinase wikiPageOutDegree "27".
- Fluorinase wikiPageRevisionID "699081641".
- Fluorinase wikiPageWikiLink Actinoplanes.
- Fluorinase wikiPageWikiLink Adenozil-chloride_synthase.
- Fluorinase wikiPageWikiLink Biomolecular_structure.
- Fluorinase wikiPageWikiLink Carbon–fluorine_bond.
- Fluorinase wikiPageWikiLink Catalysis.
- Fluorinase wikiPageWikiLink Category:EC_2.5.1.
- Fluorinase wikiPageWikiLink Category:Enzymes.
- Fluorinase wikiPageWikiLink Fluoride.
- Fluorinase wikiPageWikiLink Fluorine-18.
- Fluorinase wikiPageWikiLink L-amino-acid_oxidase.
- Fluorinase wikiPageWikiLink Methionine.
- Fluorinase wikiPageWikiLink Nocardia_brasiliensis.
- Fluorinase wikiPageWikiLink Nucleophile.
- Fluorinase wikiPageWikiLink Organofluorine_chemistry.
- Fluorinase wikiPageWikiLink Positron_emission_tomography.
- Fluorinase wikiPageWikiLink Protein_Data_Bank.
- Fluorinase wikiPageWikiLink Radioactive_tracer.
- Fluorinase wikiPageWikiLink S-Adenosyl_methionine.
- Fluorinase wikiPageWikiLink SN2_reaction.
- Fluorinase wikiPageWikiLink Salinosporamide_A.
- Fluorinase wikiPageWikiLink Selenomethionine.
- Fluorinase wikiPageWikiLink Streptomyces_cattleya.
- Fluorinase wikiPageWikiLink Turnover_number.
- Fluorinase wikiPageWikiLink File:Chlorinase_reaction.png.
- Fluorinase wikiPageWikiLink File:Fluorinase_reaction.png.
- Fluorinase wikiPageWikiLink File:Transhalogenation.png.
- Fluorinase wikiPageWikiLinkText "Fluorinase".
- Fluorinase wikiPageWikiLinkText "fluorinase".
- Fluorinase ecNumber "2.5".
- Fluorinase iubmbEcNumber "2".
- Fluorinase name "Fluorinase".
- Fluorinase wikiPageUsesTemplate Template:Alkyl_and_aryl_transferases.
- Fluorinase wikiPageUsesTemplate Template:Cite_journal.
- Fluorinase wikiPageUsesTemplate Template:EC_number.
- Fluorinase wikiPageUsesTemplate Template:Empty_section.
- Fluorinase wikiPageUsesTemplate Template:Enzyme.
- Fluorinase wikiPageUsesTemplate Template:Enzymes.
- Fluorinase wikiPageUsesTemplate Template:PDB_link.
- Fluorinase wikiPageUsesTemplate Template:Portal_bar.
- Fluorinase wikiPageUsesTemplate Template:Reflist.
- Fluorinase subject Category:EC_2.5.1.
- Fluorinase subject Category:Enzymes.
- Fluorinase type Biomolecule.
- Fluorinase type Enzyme.
- Fluorinase type Redirect.
- Fluorinase type Thing.
- Fluorinase type Q206229.
- Fluorinase type Q8047.
- Fluorinase comment "The fluorinase enzyme (EC 2.5.1.63, also known as adenosyl-fluoride synthase) catalyzes the reaction between fluoride ion and the co-factor S-adenosyl-L-methionine to generate L-methionine and 5'-fluoro-5'-deoxyadenosine, the first committed product of the fluorometabolite biosynthesis pathway. The fluorinase was originally isolated from the soil bacterium Streptomyces cattleya, but homologues have since been identified in a number of other bacterial species, including Streptomyces sp.".
- Fluorinase label "Fluorinase".
- Fluorinase sameAs Q4682288.
- Fluorinase sameAs m.03d7968.
- Fluorinase sameAs Adenozil-fluorid_sintaza.
- Fluorinase sameAs Adenozil-fluorid_sintaza.
- Fluorinase sameAs Q4682288.
- Fluorinase wasDerivedFrom Fluorinase?oldid=699081641.
- Fluorinase depiction Fluorinase_crystal_structure.png.
- Fluorinase isPrimaryTopicOf Fluorinase.
- Fluorinase name "Fluorinase (adenosyl-fluoride synthase)".