Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Fibulin> ?p ?o }
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- Fibulin abstract "Fibulin (FY-beau-lin) (now known as Fibulin-1 FBLN1) is the prototypic member of a multigene family, currently with seven members. Fibulin-1 is a calcium-binding glycoprotein. In vertebrates, fibulin-1 is found in blood and extracellular matrices. In the extracellular matrix, fibulin-1 associates with basement membranes and elastic fibers. The association with these matrix structures is mediated by its ability to interact with numerous extracellular matrix constituents including fibronectin, proteoglycans, laminins and tropoelastin. In blood, fibulin-1 binds to fibrinogen and incorporates into clots. Fibulins are secreted glycoproteins that become incorporated into a fibrillar extracellular matrix when expressed by cultured cells or added exogenously to cell monolayers. The five known members of the family share an elongated structure and many calcium-binding sites, owing to the presence of tandem arrays of epidermal growth factor-like domains. They have overlapping binding sites for several basement-membrane proteins, tropoelastin, fibrillin, fibronectin and proteoglycans, and they participate in diverse supramolecular structures. The amino-terminal domain I of fibulin consists of three anaphylatoxin-like (AT) modules, each approximately 40 residues long and containing four or six cysteines. The structure of an AT module was determined for the complement-derived anaphylatoxin C3a, and was found to be a compact alpha-helical fold that is stabilized by three disulphide bridges in the pattern Cys14, Cys25 and Cys36 (where Cys is cysteine). The bulk of the remaining portion of the fibulin molecule is a series of nine EGF-like repeats.".
- Fibulin symbol "ANATO".
- Fibulin thumbnail PDB_1c5a_EBI.jpg?width=300.
- Fibulin wikiPageID "11648371".
- Fibulin wikiPageLength "4386".
- Fibulin wikiPageOutDegree "23".
- Fibulin wikiPageRevisionID "661025870".
- Fibulin wikiPageWikiLink Anaphylatoxin.
- Fibulin wikiPageWikiLink Basement_membrane.
- Fibulin wikiPageWikiLink Blood.
- Fibulin wikiPageWikiLink Calcium-binding_protein.
- Fibulin wikiPageWikiLink Category:Blood_proteins.
- Fibulin wikiPageWikiLink Category:Protein_domains.
- Fibulin wikiPageWikiLink EFEMP1.
- Fibulin wikiPageWikiLink EFEMP2.
- Fibulin wikiPageWikiLink Elastic_fiber.
- Fibulin wikiPageWikiLink Extracellular_matrix.
- Fibulin wikiPageWikiLink FBLN1.
- Fibulin wikiPageWikiLink FBLN2.
- Fibulin wikiPageWikiLink FBLN5.
- Fibulin wikiPageWikiLink FBLN7.
- Fibulin wikiPageWikiLink Fibrinogen.
- Fibulin wikiPageWikiLink Fibronectin.
- Fibulin wikiPageWikiLink HMCN1.
- Fibulin wikiPageWikiLink Laminin.
- Fibulin wikiPageWikiLink Proteoglycan.
- Fibulin wikiPageWikiLink Tropoelastin.
- Fibulin wikiPageWikiLink Vertebrate.
- Fibulin wikiPageWikiLinkText "Fibulin".
- Fibulin wikiPageWikiLinkText "fibulin".
- Fibulin caption "Structure of porcine C5adesArg.".
- Fibulin cdd "cd00017".
- Fibulin interpro "IPR000020".
- Fibulin name "Anaphylotoxin-like domain".
- Fibulin pdb "B:693-728 :21-55 A:698-732 :698-732".
- Fibulin pfam "PF01821".
- Fibulin prosite "PDOC00906".
- Fibulin scop "1".
- Fibulin smart "ANATO".
- Fibulin symbol "ANATO".
- Fibulin wikiPageUsesTemplate Template:Biochemistry-stub.
- Fibulin wikiPageUsesTemplate Template:Calcium-binding_proteins.
- Fibulin wikiPageUsesTemplate Template:Cite_journal.
- Fibulin wikiPageUsesTemplate Template:InterPro_content.
- Fibulin wikiPageUsesTemplate Template:MeshName.
- Fibulin wikiPageUsesTemplate Template:PDB3.
- Fibulin wikiPageUsesTemplate Template:Pfam_box.
- Fibulin wikiPageUsesTemplate Template:Reflist.
- Fibulin subject Category:Blood_proteins.
- Fibulin subject Category:Protein_domains.
- Fibulin hypernym Member.
- Fibulin type Biomolecule.
- Fibulin type Person.
- Fibulin type Protein.
- Fibulin type Chemical.
- Fibulin type Domain.
- Fibulin type Thing.
- Fibulin type Q206229.
- Fibulin type Q8054.
- Fibulin comment "Fibulin (FY-beau-lin) (now known as Fibulin-1 FBLN1) is the prototypic member of a multigene family, currently with seven members. Fibulin-1 is a calcium-binding glycoprotein. In vertebrates, fibulin-1 is found in blood and extracellular matrices. In the extracellular matrix, fibulin-1 associates with basement membranes and elastic fibers.".
- Fibulin label "Fibulin".
- Fibulin sameAs Q5446488.
- Fibulin sameAs m.02rmnsw.
- Fibulin sameAs Q5446488.
- Fibulin wasDerivedFrom Fibulin?oldid=661025870.
- Fibulin depiction PDB_1c5a_EBI.jpg.
- Fibulin isPrimaryTopicOf Fibulin.