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- Fenretinide abstract "Fenretinide (4-hydroxy(phenyl)retinamide; 4-HPR) (INN) is a synthetic retinoid derivative. Retinoids are substances related to vitamin A. It has been investigated for potential use in the treatment of cancer, as well as in the treatment of cystic fibrosis, rheumatoid arthritis, acne, psoriasis, and has been found to also slow the production and accumulation of a toxin that leads to vision loss in Stargardt's patients.In cancer studies, Fenretinide treatment may cause ceramide (a wax-like substance) to build up in tumor cells and is associated with the accumulation of reactive oxygen species (ROS), resulting in cell death through apoptosis and/or necrosis. Fenretinide accumulates preferentially in fatty tissue such as the breast, which may contribute to the effectiveness of fenretinide against breast cancer. Phase III clinical trial data has suggested that fenretinide reduces breast cancer relapse in pre-menopausal women. Common side effects associated with fenretinide treatment include skin dryness and night-blindness, which is reversible upon cessation of treatment. Specific types of cancer under investigation include or have included ovarian, prostate, cervical, lung, renal, bladder, breast, glioma, skin, head and neck carcinoma, non-Hodgkin's lymphoma, neuroblastoma, and Ewing's sarcoma.".
- Fenretinide iupacName "15-[(4-hydroxyphenyl)amino]retinal".
- Fenretinide thumbnail Fenretinide.svg?width=300.
- Fenretinide wikiPageExternalLink 1664.
- Fenretinide wikiPageID "9694808".
- Fenretinide wikiPageLength "5694".
- Fenretinide wikiPageOutDegree "9".
- Fenretinide wikiPageRevisionID "677381243".
- Fenretinide wikiPageWikiLink Cancer.
- Fenretinide wikiPageWikiLink Category:Anilides.
- Fenretinide wikiPageWikiLink Category:Phenols.
- Fenretinide wikiPageWikiLink Category:Retinoids.
- Fenretinide wikiPageWikiLink Ceramide.
- Fenretinide wikiPageWikiLink Cystic_fibrosis.
- Fenretinide wikiPageWikiLink International_nonproprietary_name.
- Fenretinide wikiPageWikiLink Reactive_oxygen_species.
- Fenretinide wikiPageWikiLink Retinoid.
- Fenretinide wikiPageWikiLinkText "4HPR".
- Fenretinide wikiPageWikiLinkText "Fenretinide".
- Fenretinide wikiPageWikiLinkText "fenretinide".
- Fenretinide imagealt "Skeletal formula of fenretinide".
- Fenretinide imagealt "Space-filling model of the Fenretinide molecule".
- Fenretinide imagefile "Fenretinide 3D spacefill.png".
- Fenretinide imagefile "Fenretinide.svg".
- Fenretinide imagesize "270".
- Fenretinide imagesize "280".
- Fenretinide iupacname "15".
- Fenretinide verifiedrevid "443758270".
- Fenretinide watchedfields "changed".
- Fenretinide wikiPageUsesTemplate Template:Carotenoids.
- Fenretinide wikiPageUsesTemplate Template:Cascite.
- Fenretinide wikiPageUsesTemplate Template:Chembox.
- Fenretinide wikiPageUsesTemplate Template:Chembox_Hazards.
- Fenretinide wikiPageUsesTemplate Template:Chembox_Identifiers.
- Fenretinide wikiPageUsesTemplate Template:Chembox_Properties.
- Fenretinide wikiPageUsesTemplate Template:Chemspidercite.
- Fenretinide wikiPageUsesTemplate Template:Drugbankcite.
- Fenretinide wikiPageUsesTemplate Template:Ebicite.
- Fenretinide wikiPageUsesTemplate Template:Fdacite.
- Fenretinide wikiPageUsesTemplate Template:Keggcite.
- Fenretinide wikiPageUsesTemplate Template:Nuclear_receptor_ligands.
- Fenretinide wikiPageUsesTemplate Template:Stdinchicite.
- Fenretinide subject Category:Anilides.
- Fenretinide subject Category:Phenols.
- Fenretinide subject Category:Retinoids.
- Fenretinide type ChemicalCompound.
- Fenretinide type ChemicalSubstance.
- Fenretinide type Alcohol.
- Fenretinide type Teratogen.
- Fenretinide type Terpene.
- Fenretinide type ChemicalObject.
- Fenretinide type Thing.
- Fenretinide type Q11173.
- Fenretinide comment "Fenretinide (4-hydroxy(phenyl)retinamide; 4-HPR) (INN) is a synthetic retinoid derivative. Retinoids are substances related to vitamin A.".
- Fenretinide label "Fenretinide".
- Fenretinide sameAs Q5443576.
- Fenretinide sameAs فنترهتینید.
- Fenretinide sameAs m.02ppdcf.
- Fenretinide sameAs Fenretinid.
- Fenretinide sameAs Fenretinid.
- Fenretinide sameAs Q5443576.
- Fenretinide wasDerivedFrom Fenretinide?oldid=677381243.
- Fenretinide depiction Fenretinide.svg.
- Fenretinide isPrimaryTopicOf Fenretinide.