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- F-box_protein abstract "F-box proteins are proteins containing at least one F-box domain. The first identified F-box protein is one of three components of the SCF complex, which mediates ubiquitination of proteins targeted for degradation by the proteasome. F-box proteins have also been associated with cellular functions such as signal transduction and regulation of the cell cycle. In plants, many F-box proteins are represented in gene networks broadly regulated by microRNA-mediated gene silencing via RNA interference.In human cells, in high-iron condition, two iron atoms stabilise the F-Box FBXL5 and then the complex mediates the ubiquitination of IRP2.The F-box domain is a protein structural motif of about 50 amino acids that mediates protein–protein interactions. It was first identified in cyclin F.The F-box motif interacts directly with the SCF protein Skp1, and F-box domains commonly exist in proteins in concert with other protein–protein interaction motifs such as leucine-rich repeats and WD repeats, which are thought to mediate interactions with SCF substrates.".
- F-box_protein symbol "F-box".
- F-box_protein thumbnail PDB_1fs2_EBI.jpg?width=300.
- F-box_protein wikiPageID "9434427".
- F-box_protein wikiPageLength "3964".
- F-box_protein wikiPageOutDegree "23".
- F-box_protein wikiPageRevisionID "661023111".
- F-box_protein wikiPageWikiLink Amino_acid.
- F-box_protein wikiPageWikiLink Category:Protein_domains.
- F-box_protein wikiPageWikiLink Category:Protein_structural_motifs.
- F-box_protein wikiPageWikiLink Category:Proteins.
- F-box_protein wikiPageWikiLink Cell_cycle.
- F-box_protein wikiPageWikiLink Cyclin.
- F-box_protein wikiPageWikiLink FBXL5.
- F-box_protein wikiPageWikiLink Gene_regulatory_network.
- F-box_protein wikiPageWikiLink Gene_silencing.
- F-box_protein wikiPageWikiLink Iron-responsive_element-binding_protein.
- F-box_protein wikiPageWikiLink Leucine-rich_repeat.
- F-box_protein wikiPageWikiLink MicroRNA.
- F-box_protein wikiPageWikiLink Proteasome.
- F-box_protein wikiPageWikiLink Protein.
- F-box_protein wikiPageWikiLink Protein–protein_interaction.
- F-box_protein wikiPageWikiLink RNA_interference.
- F-box_protein wikiPageWikiLink SCF_complex.
- F-box_protein wikiPageWikiLink SKP1A.
- F-box_protein wikiPageWikiLink Signal_transduction.
- F-box_protein wikiPageWikiLink Structural_motif.
- F-box_protein wikiPageWikiLink Ubiquitin.
- F-box_protein wikiPageWikiLink WD40_repeat.
- F-box_protein wikiPageWikiLinkText "F-box protein".
- F-box_protein wikiPageWikiLinkText "F-box".
- F-box_protein wikiPageWikiLinkText "FWD1".
- F-box_protein caption "Structure of the Skp1-Skp2 complex.".
- F-box_protein interpro "IPR001810".
- F-box_protein name "F-box domain".
- F-box_protein pdb ", , , , , , , , , ,".
- F-box_protein pfam "PF00646".
- F-box_protein pfamClan "CL0271".
- F-box_protein prosite "PS50181".
- F-box_protein scop "1".
- F-box_protein smart "SM00256".
- F-box_protein symbol "F-box".
- F-box_protein wikiPageUsesTemplate Template:Carrier_proteins.
- F-box_protein wikiPageUsesTemplate Template:Citation_needed.
- F-box_protein wikiPageUsesTemplate Template:Cite_journal.
- F-box_protein wikiPageUsesTemplate Template:Infobox_protein_family.
- F-box_protein wikiPageUsesTemplate Template:MeshName.
- F-box_protein wikiPageUsesTemplate Template:PDB2.
- F-box_protein wikiPageUsesTemplate Template:Protein-stub.
- F-box_protein wikiPageUsesTemplate Template:Refbegin.
- F-box_protein wikiPageUsesTemplate Template:Refend.
- F-box_protein wikiPageUsesTemplate Template:Reflist.
- F-box_protein subject Category:Protein_domains.
- F-box_protein subject Category:Protein_structural_motifs.
- F-box_protein subject Category:Proteins.
- F-box_protein hypernym Proteins.
- F-box_protein type Biomolecule.
- F-box_protein type Protein.
- F-box_protein type Biomolecule.
- F-box_protein type Chemical.
- F-box_protein type Domain.
- F-box_protein type Nutrient.
- F-box_protein type Thing.
- F-box_protein type Q206229.
- F-box_protein type Q8054.
- F-box_protein comment "F-box proteins are proteins containing at least one F-box domain. The first identified F-box protein is one of three components of the SCF complex, which mediates ubiquitination of proteins targeted for degradation by the proteasome. F-box proteins have also been associated with cellular functions such as signal transduction and regulation of the cell cycle.".
- F-box_protein label "F-box protein".
- F-box_protein sameAs Q5423632.
- F-box_protein sameAs m.0288tm5.
- F-box_protein sameAs Белки_F-box.
- F-box_protein sameAs Q5423632.
- F-box_protein wasDerivedFrom F-box_protein?oldid=661023111.
- F-box_protein depiction PDB_1fs2_EBI.jpg.
- F-box_protein isPrimaryTopicOf F-box_protein.