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- Eye_development abstract "Eye formation in the human embryo begins at approximately 3 weeks into embryonic development and continues through the tenth week. Cells from both the mesodermal and the ectodermal tissues contribute to the formation of the eye. Specifically, the eye is derived from the neuroepithelium, surface ectoderm, and the extracellular mesenchyme which consists of both the neural crest and mesoderm.[2] Neuroepithelium forms the retina, ciliary body, iris, and optic nerves. Surface ectoderm forms the lens, corneal epithelium and eyelid. The extracellular mesenchyme forms the sclera, cornea, blood vessels, muscles, and vitreous.The eye begins to develop as a pair of optic vesicles on each side of the forebrain at the end of the 4th week of pregnancy. Optic vesicles are outgrowings of the brain which make contact with the surface ectoderm and this contact induces changes necessary for further development of the eye. Through a groove at the bottom of the optic vesicle known as choroid fissure the blood vessels enter the eye. Several layers such as the neural tube, neural crest, surface ectoderm, and mesoderm contribute to the development of the eye.Eye development is initiated by the master control gene Pax-6, a homeobox gene known as Andridia in humans, small eye in mouse, and eyeless in Drosphilia. The Pax-6 gene locus is a transcription factor for the various genes and growth factors involved in eye formation. Eye morphogenesis begins with the evagination, or outgrowth, of the optic grooves or sulci. These two grooves in the neural folds transform into optic vesicles with the closure of the neural tube. The optic vesicles then develop into the optic cup with the inner layer forming the retina and the outer portion forming the retinal pigment epithelium. The middle portion of the optic cup develops into the ciliary body and iris. During the invagination of the optic cup, the ectoderm begins to thicken and form the lens placode, which eventually separates from the ectoderm to form the lens vesicle at the open end of the optic cup. Further differentiation and mechanical rearrangement of cells in and around the optic cup gives rise to the fully developed eye.".
- Eye_development thumbnail Gray863.png?width=300.
- Eye_development wikiPageExternalLink lecture17.htm.
- Eye_development wikiPageID "8133296".
- Eye_development wikiPageLength "14350".
- Eye_development wikiPageOutDegree "71".
- Eye_development wikiPageRevisionID "689996267".
- Eye_development wikiPageWikiLink Anterior_segment_of_eyeball.
- Eye_development wikiPageWikiLink Blood_vessel.
- Eye_development wikiPageWikiLink Category:Embryology_of_nervous_system.
- Eye_development wikiPageWikiLink Category:Eye.
- Eye_development wikiPageWikiLink Choroid.
- Eye_development wikiPageWikiLink Choroid_fissure.
- Eye_development wikiPageWikiLink Ciliary_body.
- Eye_development wikiPageWikiLink Cornea.
- Eye_development wikiPageWikiLink Corneal_epithelium.
- Eye_development wikiPageWikiLink Cyclopia.
- Eye_development wikiPageWikiLink Descemets_membrane.
- Eye_development wikiPageWikiLink Drosphilia.
- Eye_development wikiPageWikiLink Ectoderm.
- Eye_development wikiPageWikiLink Embryo.
- Eye_development wikiPageWikiLink Endoderm.
- Eye_development wikiPageWikiLink Endodermic_evagination.
- Eye_development wikiPageWikiLink Endothelium.
- Eye_development wikiPageWikiLink Extraocular_muscles.
- Eye_development wikiPageWikiLink Eye.
- Eye_development wikiPageWikiLink Eyelid.
- Eye_development wikiPageWikiLink Gastrulation.
- Eye_development wikiPageWikiLink Invagination.
- Eye_development wikiPageWikiLink Iris_(anatomy).
- Eye_development wikiPageWikiLink LMX1B.
- Eye_development wikiPageWikiLink Lens_(anatomy).
- Eye_development wikiPageWikiLink Lens_placode.
- Eye_development wikiPageWikiLink Lens_vesicle.
- Eye_development wikiPageWikiLink Mesoderm.
- Eye_development wikiPageWikiLink Muscle.
- Eye_development wikiPageWikiLink Neural_crest.
- Eye_development wikiPageWikiLink Neural_plate.
- Eye_development wikiPageWikiLink Neural_tube.
- Eye_development wikiPageWikiLink Neuroectoderm.
- Eye_development wikiPageWikiLink Neuroepithelial_cell.
- Eye_development wikiPageWikiLink Neurulation.
- Eye_development wikiPageWikiLink Optic_cup_(embryology).
- Eye_development wikiPageWikiLink Optic_nerve.
- Eye_development wikiPageWikiLink Optic_vesicle.
- Eye_development wikiPageWikiLink PAX6.
- Eye_development wikiPageWikiLink Retina.
- Eye_development wikiPageWikiLink Retinoic_acid.
- Eye_development wikiPageWikiLink Sclera.
- Eye_development wikiPageWikiLink Sonic_hedgehog.
- Eye_development wikiPageWikiLink Stroma_of_cornea.
- Eye_development wikiPageWikiLink Surface_ectoderm.
- Eye_development wikiPageWikiLink Vitamin_A.
- Eye_development wikiPageWikiLink Vitamin_A_deficiency.
- Eye_development wikiPageWikiLink Vitreous_membrane.
- Eye_development wikiPageWikiLink File:Gray863.png.
- Eye_development wikiPageWikiLink File:Gray864.png.
- Eye_development wikiPageWikiLinkText "Eye development".
- Eye_development wikiPageWikiLinkText "eye development".
- Eye_development wikiPageUsesTemplate Template:Development_of_eye_and_ear.
- Eye_development wikiPageUsesTemplate Template:Reflist.
- Eye_development subject Category:Embryology_of_nervous_system.
- Eye_development subject Category:Eye.
- Eye_development type Feature.
- Eye_development comment "Eye formation in the human embryo begins at approximately 3 weeks into embryonic development and continues through the tenth week. Cells from both the mesodermal and the ectodermal tissues contribute to the formation of the eye. Specifically, the eye is derived from the neuroepithelium, surface ectoderm, and the extracellular mesenchyme which consists of both the neural crest and mesoderm.[2] Neuroepithelium forms the retina, ciliary body, iris, and optic nerves.".
- Eye_development label "Eye development".
- Eye_development sameAs Q5422650.
- Eye_development sameAs Augenentwicklung_(Wirbeltiere).
- Eye_development sameAs Dxc3xa9veloppement_de_lxc5x93il_des_vertxc3xa9brxc3xa9s.
- Eye_development sameAs m.026st9c.
- Eye_development sameAs Q5422650.
- Eye_development wasDerivedFrom Eye_development?oldid=689996267.
- Eye_development depiction Gray863.png.
- Eye_development isPrimaryTopicOf Eye_development.