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- Evans_Blue_(dye) abstract "T-1824 or Evans Blue, often incorrectly rendered as Evan's Blue, is an azo dye which has a very high affinity for serum albumin. Because of this, it can be useful in physiology in estimating the proportion of body water contained in blood plasma.Evans blue dye has been used as a viability assay on the basis of its penetration into non-viable cells, although the method is subject to error because it assumes that damaged or otherwise altered cells are not capable of repair and therefore are notviable.Evans blue is also used to assess the permeability of the blood–brain barrier to macromolecules. Because serum albumin cannot cross the barrier, and virtually all Evans Blue is bound to albumin, normally the neural tissue remains unstained. When the BBB has been compromised, albumin-bound Evans blue enters the CNS. It fluoresces with excitation peaks at 470 and 540 nm and an emission peak at 680 nm. Evans blue is pharmacologically active, acting as a negative allosteric modulator of the AMPA and kainate receptors and as an inhibitor of vesicular glutamate transporters. It also acts on P2 receptors.It was named after Herbert McLean Evans, an American chemist.".
- Evans_Blue_(dye) iupacName "tetrasodium (6E,6'E)-6,6-[(3,3'-dimethylbiphenyl-4,4'-diyl)di(1E)hydrazin-2-yl-1-ylidene]bis(4-amino-5-oxo-5,6-dihydronaphthalene-1,3-disulfonate)".
- Evans_Blue_(dye) thumbnail Evans_Blue.svg?width=300.
- Evans_Blue_(dye) wikiPageID "5310657".
- Evans_Blue_(dye) wikiPageLength "4100".
- Evans_Blue_(dye) wikiPageOutDegree "19".
- Evans_Blue_(dye) wikiPageRevisionID "707101541".
- Evans_Blue_(dye) wikiPageWikiLink AMPA_receptor.
- Evans_Blue_(dye) wikiPageWikiLink Allosteric_modulator.
- Evans_Blue_(dye) wikiPageWikiLink Azo_compound.
- Evans_Blue_(dye) wikiPageWikiLink Blood_plasma.
- Evans_Blue_(dye) wikiPageWikiLink Blood–brain_barrier.
- Evans_Blue_(dye) wikiPageWikiLink Body_water.
- Evans_Blue_(dye) wikiPageWikiLink Category:AMPA_receptor_antagonists.
- Evans_Blue_(dye) wikiPageWikiLink Category:Azo_dyes.
- Evans_Blue_(dye) wikiPageWikiLink Category:Kainate_receptor_antagonists.
- Evans_Blue_(dye) wikiPageWikiLink Category:Naphthalenesulfonates.
- Evans_Blue_(dye) wikiPageWikiLink Category:Naphthylamines.
- Evans_Blue_(dye) wikiPageWikiLink Glutamate_transporter.
- Evans_Blue_(dye) wikiPageWikiLink Herbert_McLean_Evans.
- Evans_Blue_(dye) wikiPageWikiLink Kainate_receptor.
- Evans_Blue_(dye) wikiPageWikiLink P2_receptor.
- Evans_Blue_(dye) wikiPageWikiLink Physiology.
- Evans_Blue_(dye) wikiPageWikiLink Reuptake_inhibitor.
- Evans_Blue_(dye) wikiPageWikiLink Serum_albumin.
- Evans_Blue_(dye) wikiPageWikiLink Viability_assay.
- Evans_Blue_(dye) wikiPageWikiLinkText "Evans Blue (dye)".
- Evans_Blue_(dye) imagealt "Space-filling model of the Evans blue molecule, sodium salt".
- Evans_Blue_(dye) imagefile "Evans Blue.svg".
- Evans_Blue_(dye) imagefile "Evans blue sodium 3D spacefill.png".
- Evans_Blue_(dye) imagesize "310".
- Evans_Blue_(dye) iupacname "tetrasodium -6,6-[dihydrazin-2-yl-1-ylidene]bis".
- Evans_Blue_(dye) verifiedfields "changed".
- Evans_Blue_(dye) verifiedrevid "417240354".
- Evans_Blue_(dye) watchedfields "changed".
- Evans_Blue_(dye) wikiPageUsesTemplate Template:Cascite.
- Evans_Blue_(dye) wikiPageUsesTemplate Template:Chembox.
- Evans_Blue_(dye) wikiPageUsesTemplate Template:Chembox_Hazards.
- Evans_Blue_(dye) wikiPageUsesTemplate Template:Chembox_Identifiers.
- Evans_Blue_(dye) wikiPageUsesTemplate Template:Chembox_Properties.
- Evans_Blue_(dye) wikiPageUsesTemplate Template:Citation_needed.
- Evans_Blue_(dye) wikiPageUsesTemplate Template:Cite_journal.
- Evans_Blue_(dye) wikiPageUsesTemplate Template:Ebicite.
- Evans_Blue_(dye) wikiPageUsesTemplate Template:For.
- Evans_Blue_(dye) wikiPageUsesTemplate Template:Glutamatergics.
- Evans_Blue_(dye) wikiPageUsesTemplate Template:Keggcite.
- Evans_Blue_(dye) wikiPageUsesTemplate Template:Purinergics.
- Evans_Blue_(dye) subject Category:AMPA_receptor_antagonists.
- Evans_Blue_(dye) subject Category:Azo_dyes.
- Evans_Blue_(dye) subject Category:Kainate_receptor_antagonists.
- Evans_Blue_(dye) subject Category:Naphthalenesulfonates.
- Evans_Blue_(dye) subject Category:Naphthylamines.
- Evans_Blue_(dye) hypernym Dye.
- Evans_Blue_(dye) type ChemicalCompound.
- Evans_Blue_(dye) type ChemicalSubstance.
- Evans_Blue_(dye) type Chemical.
- Evans_Blue_(dye) type Sulfonate.
- Evans_Blue_(dye) type ChemicalObject.
- Evans_Blue_(dye) type Thing.
- Evans_Blue_(dye) type Q11173.
- Evans_Blue_(dye) comment "T-1824 or Evans Blue, often incorrectly rendered as Evan's Blue, is an azo dye which has a very high affinity for serum albumin.".
- Evans_Blue_(dye) label "Evans Blue (dye)".
- Evans_Blue_(dye) sameAs Q5415983.
- Evans_Blue_(dye) sameAs Evansi_sinine.
- Evans_Blue_(dye) sameAs آبی_اوانز.
- Evans_Blue_(dye) sameAs m.02p963z.
- Evans_Blue_(dye) sameAs T-1824.
- Evans_Blue_(dye) sameAs T-1824.
- Evans_Blue_(dye) sameAs Q5415983.
- Evans_Blue_(dye) wasDerivedFrom Evans_Blue_(dye)?oldid=707101541.
- Evans_Blue_(dye) depiction Evans_Blue.svg.
- Evans_Blue_(dye) isPrimaryTopicOf Evans_Blue_(dye).