Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/Epothilone> ?p ?o }
- Epothilone abstract "The epothilones are a class of potential cancer drugs. Like taxanes, they prevent cancer cells from dividing by interfering with tubulin, but in early trials epithilones have better efficacy and milder adverse effects than taxanes.As of September 2008, epothilones A to F have been identified and characterised.Early studies in cancer cell lines and in human cancer patients indicate superior efficacy to the taxanes. Their mechanism of action is similar, but their chemical structure is simpler. Due to their better water solubility, cremophors (solubilizing agents used for paclitaxel which can affect cardiac function and cause severe hypersensitivity) are not needed. Endotoxin-like properties known from paclitaxel, like activation of macrophages synthesizing inflammatory cytokines and nitric oxide, are not observed for epothilone B.Epothilones were originally identified as metabolites produced by the soil-dwelling myxobacterium Sorangium cellulosum.".
- Epothilone thumbnail Epothilone_A_B.svg?width=300.
- Epothilone wikiPageID "5139511".
- Epothilone wikiPageLength "18200".
- Epothilone wikiPageOutDegree "89".
- Epothilone wikiPageRevisionID "651487330".
- Epothilone wikiPageWikiLink Acetate.
- Epothilone wikiPageWikiLink Aldehyde.
- Epothilone wikiPageWikiLink Aldol_reaction.
- Epothilone wikiPageWikiLink Alkane.
- Epothilone wikiPageWikiLink Alkene.
- Epothilone wikiPageWikiLink Amino_acid.
- Epothilone wikiPageWikiLink CAS_Registry_Number.
- Epothilone wikiPageWikiLink Carrier_protein.
- Epothilone wikiPageWikiLink Category:Epoxides.
- Epothilone wikiPageWikiLink Category:Lactams.
- Epothilone wikiPageWikiLink Category:Mitotic_inhibitors.
- Epothilone wikiPageWikiLink Category:Thiazoles.
- Epothilone wikiPageWikiLink Category:Total_synthesis.
- Epothilone wikiPageWikiLink Chemical_formula.
- Epothilone wikiPageWikiLink Coenzyme_A.
- Epothilone wikiPageWikiLink Cysteine.
- Epothilone wikiPageWikiLink Diisobutylaluminium_hydride.
- Epothilone wikiPageWikiLink Diisopinocampheylborane.
- Epothilone wikiPageWikiLink Discodermolide.
- Epothilone wikiPageWikiLink RAMP_hydrazone-alkylation_reaction.
- Epothilone wikiPageWikiLink Epimer.
- Epothilone wikiPageWikiLink Epoxide.
- Epothilone wikiPageWikiLink Ester.
- Epothilone wikiPageWikiLink European_Medicines_Agency.
- Epothilone wikiPageWikiLink Food_and_Drug_Administration.
- Epothilone wikiPageWikiLink Glycidol.
- Epothilone wikiPageWikiLink Grignard_reaction.
- Epothilone wikiPageWikiLink Grubbs_catalyst.
- Epothilone wikiPageWikiLink Hydrogenolysis.
- Epothilone wikiPageWikiLink Hydroxyl.
- Epothilone wikiPageWikiLink Ixabepilone.
- Epothilone wikiPageWikiLink K._C._Nicolaou.
- Epothilone wikiPageWikiLink Lead(IV)_acetate.
- Epothilone wikiPageWikiLink Lindgren_oxidation.
- Epothilone wikiPageWikiLink Macrolactone.
- Epothilone wikiPageWikiLink Metabolite.
- Epothilone wikiPageWikiLink Methyl_group.
- Epothilone wikiPageWikiLink Methylation.
- Epothilone wikiPageWikiLink Microtubule.
- Epothilone wikiPageWikiLink Molecular_mass.
- Epothilone wikiPageWikiLink Myxobacteria.
- Epothilone wikiPageWikiLink Nonribosomal_peptide.
- Epothilone wikiPageWikiLink Olefin_metathesis.
- Epothilone wikiPageWikiLink Osmium_tetroxide.
- Epothilone wikiPageWikiLink Ovarian_cancer.
- Epothilone wikiPageWikiLink Ozonolysis.
- Epothilone wikiPageWikiLink Paclitaxel.
- Epothilone wikiPageWikiLink Patupilone.
- Epothilone wikiPageWikiLink Phosphopantheteine.
- Epothilone wikiPageWikiLink Pinnick_oxidation.
- Epothilone wikiPageWikiLink Polyketide.
- Epothilone wikiPageWikiLink Polyketide_synthase.
- Epothilone wikiPageWikiLink PubChem.
- Epothilone wikiPageWikiLink Sagopilone.
- Epothilone wikiPageWikiLink Silyl_ether.
- Epothilone wikiPageWikiLink Sorangium_cellulosum.
- Epothilone wikiPageWikiLink Stereocenter.
- Epothilone wikiPageWikiLink Structural_analog.
- Epothilone wikiPageWikiLink Swern_oxidation.
- Epothilone wikiPageWikiLink Taxane.
- Epothilone wikiPageWikiLink Tetrapropylammonium_perruthenate.
- Epothilone wikiPageWikiLink Thiazole.
- Epothilone wikiPageWikiLink Thin-layer_chromatography.
- Epothilone wikiPageWikiLink Total_synthesis.
- Epothilone wikiPageWikiLink Tubulin.
- Epothilone wikiPageWikiLink Wikipedia:Chemical_infobox.
- Epothilone wikiPageWikiLink Wittig_reaction.
- Epothilone wikiPageWikiLink X-ray_crystallography.
- Epothilone wikiPageWikiLink Yamaguchi_esterification.
- Epothilone wikiPageWikiLink File:Construction_of_building_blocks_for_Nicolaous_total_synthesis_of_epothilone_B_(1997).png.
- Epothilone wikiPageWikiLink File:Epothilone_A_B.svg.
- Epothilone wikiPageWikiLink File:Epothilone_C_D.svg.
- Epothilone wikiPageWikiLink File:Epothilone_E_F.svg.
- Epothilone wikiPageWikiLink File:Nicolaous_retrosynthesis_of_epothilone_B_(1997).png.
- Epothilone wikiPageWikiLink File:Nicolaous_total_synthesis_of_epothilone_B_(1997).png.
- Epothilone wikiPageWikiLinkText "Epothilone A".
- Epothilone wikiPageWikiLinkText "Epothilone".
- Epothilone wikiPageWikiLinkText "epothilone A".
- Epothilone wikiPageWikiLinkText "epothilone".
- Epothilone wikiPageUsesTemplate Template:As_of.
- Epothilone wikiPageUsesTemplate Template:Reflist.
- Epothilone subject Category:Epoxides.
- Epothilone subject Category:Lactams.
- Epothilone subject Category:Mitotic_inhibitors.
- Epothilone subject Category:Thiazoles.
- Epothilone subject Category:Total_synthesis.
- Epothilone hypernym Drugs.
- Epothilone type Drug.
- Epothilone type Amide.
- Epothilone type Azole.
- Epothilone type Drug.
- Epothilone type Ether.
- Epothilone type Heterocycle.
- Epothilone type Inhibitor.