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- Env_(gene) abstract "Env is a viral protein that serves to form the viral envelope. The expression of the env gene enables retroviruses to target and attach to specific cell types, and to infiltrate the target cell membrane.Analysis of the structure and sequence of several different env genes suggests that Env proteins are type 1 fusion machines. Type 1 fusion machines initially bind a receptor on the target cell surface, which triggers a conformational change, allowing for binding of the fusion protein. The fusion peptide inserts itself in the host cell membrane and brings the host cell membrane very close to the viral membrane to facilitate membrane fusion.While there are significant differences in sequence of the env gene between retroviruses, the gene is always located downstream of gag, pro, and pol. The env mRNA must be spliced for expression.The mature product of the env gene is the viral spike protein, which has two main parts: the surface protein (SU) and the transmembrane protein (TM). The tropism of the virus is determined by the SU protein domain because it is responsible for the receptor-binding function of the virus. The SU domain therefore determines the specificity of the virus for a single receptor molecule.".
- Env_(gene) wikiPageID "9876980".
- Env_(gene) wikiPageLength "16399".
- Env_(gene) wikiPageOutDegree "46".
- Env_(gene) wikiPageRevisionID "694390497".
- Env_(gene) wikiPageWikiLink Antibody.
- Env_(gene) wikiPageWikiLink Avian_sarcoma_leukosis_virus.
- Env_(gene) wikiPageWikiLink CD4.
- Env_(gene) wikiPageWikiLink Category:Viral_proteins.
- Env_(gene) wikiPageWikiLink Co-receptor.
- Env_(gene) wikiPageWikiLink Conformational_isomerism.
- Env_(gene) wikiPageWikiLink Covalent_bond.
- Env_(gene) wikiPageWikiLink Endoplasmic_reticulum.
- Env_(gene) wikiPageWikiLink Enfuvirtide.
- Env_(gene) wikiPageWikiLink Entry_inhibitor.
- Env_(gene) wikiPageWikiLink Envelope_glycoprotein_GP120.
- Env_(gene) wikiPageWikiLink Epithelium.
- Env_(gene) wikiPageWikiLink Furin.
- Env_(gene) wikiPageWikiLink Glycoprotein.
- Env_(gene) wikiPageWikiLink Glycosylation.
- Env_(gene) wikiPageWikiLink HIV.
- Env_(gene) wikiPageWikiLink HIV_vaccine.
- Env_(gene) wikiPageWikiLink Immunoreceptor_tyrosine-based_activation_motif.
- Env_(gene) wikiPageWikiLink List_of_Transformers:_Super-God_Masterforce_characters.
- Env_(gene) wikiPageWikiLink Membrane_fusion_protein.
- Env_(gene) wikiPageWikiLink Messenger_RNA.
- Env_(gene) wikiPageWikiLink Mouse_mammary_tumor_virus.
- Env_(gene) wikiPageWikiLink Murine_leukemia_virus.
- Env_(gene) wikiPageWikiLink PH.
- Env_(gene) wikiPageWikiLink Phenotype.
- Env_(gene) wikiPageWikiLink Protease.
- Env_(gene) wikiPageWikiLink Protein_dimer.
- Env_(gene) wikiPageWikiLink Receptor_(biochemistry).
- Env_(gene) wikiPageWikiLink Retrovirus.
- Env_(gene) wikiPageWikiLink Rev_(HIV).
- Env_(gene) wikiPageWikiLink Subtypes_of_HIV.
- Env_(gene) wikiPageWikiLink T_helper_cell.
- Env_(gene) wikiPageWikiLink Tissue_tropism.
- Env_(gene) wikiPageWikiLink Trans-acting.
- Env_(gene) wikiPageWikiLink Tunicamycin.
- Env_(gene) wikiPageWikiLink Viral_entry.
- Env_(gene) wikiPageWikiLink Viral_envelope.
- Env_(gene) wikiPageWikiLink Viral_protein.
- Env_(gene) wikiPageWikiLink File:HI-virion-structure_en.svg.
- Env_(gene) wikiPageWikiLinkText "''env'' gene".
- Env_(gene) wikiPageWikiLinkText "''env''".
- Env_(gene) wikiPageWikiLinkText "Env (gene)".
- Env_(gene) wikiPageWikiLinkText "Env".
- Env_(gene) wikiPageWikiLinkText "HIV envelope gene".
- Env_(gene) wikiPageWikiLinkText "env (gene)".
- Env_(gene) wikiPageWikiLinkText "env gene".
- Env_(gene) wikiPageWikiLinkText "env".
- Env_(gene) wikiPageWikiLinkText "envelope".
- Env_(gene) chromosome "viral genome".
- Env_(gene) entrezchromosome "NC_001802.1".
- Env_(gene) entrezgene "155971".
- Env_(gene) genlocEnd "8341".
- Env_(gene) genlocStart "5771".
- Env_(gene) name "env gp160; envelope glycoprotein".
- Env_(gene) organism "HIV 1".
- Env_(gene) refseqprotein "NP_057856.1".
- Env_(gene) symbol "env".
- Env_(gene) taxid "11676".
- Env_(gene) uniprot "P04578".
- Env_(gene) wikiPageUsesTemplate Template:Citation_needed.
- Env_(gene) wikiPageUsesTemplate Template:Infobox_nonhuman_protein.
- Env_(gene) wikiPageUsesTemplate Template:Main.
- Env_(gene) wikiPageUsesTemplate Template:MeshName.
- Env_(gene) wikiPageUsesTemplate Template:Reflist.
- Env_(gene) wikiPageUsesTemplate Template:Viral_proteins.
- Env_(gene) subject Category:Viral_proteins.
- Env_(gene) hypernym Protein.
- Env_(gene) type Protein.
- Env_(gene) type Redirect.
- Env_(gene) comment "Env is a viral protein that serves to form the viral envelope. The expression of the env gene enables retroviruses to target and attach to specific cell types, and to infiltrate the target cell membrane.Analysis of the structure and sequence of several different env genes suggests that Env proteins are type 1 fusion machines. Type 1 fusion machines initially bind a receptor on the target cell surface, which triggers a conformational change, allowing for binding of the fusion protein.".
- Env_(gene) label "Env (gene)".
- Env_(gene) sameAs Q5380903.
- Env_(gene) sameAs m.05b6nfr.
- Env_(gene) sameAs Q5380903.
- Env_(gene) sameAs Env_(基因).
- Env_(gene) wasDerivedFrom Env_(gene)?oldid=694390497.
- Env_(gene) isPrimaryTopicOf Env_(gene).