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- Endocyte abstract "Endocyte (NASDAQ: ECYT) is a biopharmaceutical company established in 1996 and headquartered in West Lafayette, Indiana, a resident of the Purdue Research Park. In 2011 the company completed successfully an initial public offering (IPO). As of 2013, the company had 93 employees. The president and CEO of the company is Ron Ellis.Endocyte is advancing the first technology platform for the creation of small molecule drug conjugates (a.k.a. SMDCs), which consist of a small molecule linked to a potent drug, and is developing a pipeline of SMDCs together with non-invasive companion imaging agents for cancer, inflammatory diseases and kidney disease (autosomal-dominant polycystic kidney disease/ADPKDor PKD). Endocyte’s lead drug candidate is vintafolide, an investigational targeted cancer therapeutic in late-stage development. In 2012 marketing rights were acquired by Merck for $120 million in an upfront payment and up to $880 million in milestone payments.Vintafolide is a small molecule drug conjugate consisting of a small molecule targeting the folate receptor, which is expressed on many cancers, such as ovarian cancer, and a potent chemotherapy drug, a derivative of vinblastine. Endocyte retained rights to the development and commercialization of etarfolatide.Endocyte’s other preclinical drug candidates also target the folate receptor as well as prostate-specific membrane antigen (PSMA) receptors.The company was formed based on technology developed by Philip Low (the company's CSO), and Christopher Leamon, PhD, the company’s VP of research. This technology is a folic acid-based drug delivery system, referred to now as folate targeting. The company is also developing SMDCs with varying drug payloads as well as different ligands for other molecular targets, such as prostate-specific membrane antigen (PMSA) and has also developed, with Bristol-Myers Squibb, an epothilone-folic acid conjugate (BMS-753493), described at a 2008 conference.".
- Endocyte foundingYear "1996".
- Endocyte industry Biopharmaceutical_industry.
- Endocyte keyPerson Chief_executive_officer.
- Endocyte keyPerson President.
- Endocyte numberOfEmployees "93".
- Endocyte type Public.
- Endocyte wikiPageExternalLink www.endocyte.com.
- Endocyte wikiPageID "39669742".
- Endocyte wikiPageLength "6691".
- Endocyte wikiPageOutDegree "26".
- Endocyte wikiPageRevisionID "687548429".
- Endocyte wikiPageWikiLink Biopharmaceutical.
- Endocyte wikiPageWikiLink Biopharmaceutical_industry.
- Endocyte wikiPageWikiLink Bristol-Myers_Squibb.
- Endocyte wikiPageWikiLink Category:1996_establishments_in_Indiana.
- Endocyte wikiPageWikiLink Category:Companies_based_in_Indiana.
- Endocyte wikiPageWikiLink Category:Companies_listed_on_NASDAQ.
- Endocyte wikiPageWikiLink Category:Pharmaceutical_companies_of_the_United_States.
- Endocyte wikiPageWikiLink Chief_executive_officer.
- Endocyte wikiPageWikiLink Chief_science_officer.
- Endocyte wikiPageWikiLink Epothilone.
- Endocyte wikiPageWikiLink Folate_receptor.
- Endocyte wikiPageWikiLink Folate_targeting.
- Endocyte wikiPageWikiLink Glutamate_carboxypeptidase_II.
- Endocyte wikiPageWikiLink Initial_public_offering.
- Endocyte wikiPageWikiLink Merck_&_Co..
- Endocyte wikiPageWikiLink NASDAQ.
- Endocyte wikiPageWikiLink President.
- Endocyte wikiPageWikiLink Public.
- Endocyte wikiPageWikiLink Purdue_Research_Park.
- Endocyte wikiPageWikiLink Small_molecule_drug_conjugate.
- Endocyte wikiPageWikiLink Vinblastine.
- Endocyte wikiPageWikiLink Vintafolide.
- Endocyte wikiPageWikiLink West_Lafayette,_Indiana.
- Endocyte wikiPageWikiLinkText "Endocyte".
- Endocyte homepage www.endocyte.com.
- Endocyte industry Biopharmaceutical_industry.
- Endocyte keyPeople "Ron Ellis, President and CEO".
- Endocyte locationCity "West Lafayette, Indiana".
- Endocyte locationCountry "United State".
- Endocyte name "Endocyte".
- Endocyte numEmployees "93".
- Endocyte type Public.
- Endocyte wikiPageUsesTemplate Template:As_of.
- Endocyte wikiPageUsesTemplate Template:Infobox_company.
- Endocyte wikiPageUsesTemplate Template:Reflist.
- Endocyte wikiPageUsesTemplate Template:Start_date.
- Endocyte subject Category:1996_establishments_in_Indiana.
- Endocyte subject Category:Companies_based_in_Indiana.
- Endocyte subject Category:Companies_listed_on_NASDAQ.
- Endocyte subject Category:Pharmaceutical_companies_of_the_United_States.
- Endocyte hypernym Company.
- Endocyte type Agent.
- Endocyte type Company.
- Endocyte type Organisation.
- Endocyte type Organization.
- Endocyte type Agent.
- Endocyte type SocialPerson.
- Endocyte type Thing.
- Endocyte type Q43229.
- Endocyte comment "Endocyte (NASDAQ: ECYT) is a biopharmaceutical company established in 1996 and headquartered in West Lafayette, Indiana, a resident of the Purdue Research Park. In 2011 the company completed successfully an initial public offering (IPO). As of 2013, the company had 93 employees. The president and CEO of the company is Ron Ellis.Endocyte is advancing the first technology platform for the creation of small molecule drug conjugates (a.k.a.".
- Endocyte label "Endocyte".
- Endocyte sameAs Q17108676.
- Endocyte sameAs m.04d2_fk.
- Endocyte sameAs Q17108676.
- Endocyte wasDerivedFrom Endocyte?oldid=687548429.
- Endocyte homepage www.endocyte.com.
- Endocyte isPrimaryTopicOf Endocyte.
- Endocyte name "Endocyte".