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- Elbasvir abstract "Elbasvir (MK-8742) is a drug approved for the treatment of hepatitis C. It was developed by Merck and completed Phase III trials, following promising results in Phase II when used in combination with the NS3/4a protease inhibitor grazoprevir, either with or without ribavirin.Elbasvir is a highly potent and selective inhibitor of the hepatitis C virus NS5a replication complex. It has only been investigated as a combination product with other complementary hepatitis C antiviral drugs such as grazoprevir and MK-3682, and it is unclear whether elbasvir would show robust antiviral activity if it was administered by itself. Nevertheless, combination products of this type represent the most successful approach yet developed for actually curing hepatitis C, rather than merely slowing the progression of the disease.".
- Elbasvir casNumber "1370468-36-2".
- Elbasvir iupacName "Dimethyl N,N’-([(6S)-6H-indolo[1,2-c][1,3]benzoxazine-3,10-diyl]bis{1H-imidazole-5,2-diyl-(2S)-pyrrolidine-2,1-diyl[(2S)-1-oxo-3-methylbutane-1,2-diyl]})biscarbamate".
- Elbasvir thumbnail Elbasvir.svg?width=300.
- Elbasvir wikiPageID "46273987".
- Elbasvir wikiPageLength "5862".
- Elbasvir wikiPageOutDegree "11".
- Elbasvir wikiPageRevisionID "702599134".
- Elbasvir wikiPageWikiLink Category:Anti-hepatitis_C_agents.
- Elbasvir wikiPageWikiLink Category:Carbamates.
- Elbasvir wikiPageWikiLink Category:Imidazoles.
- Elbasvir wikiPageWikiLink Category:Pyrrolidines.
- Elbasvir wikiPageWikiLink Drug_development.
- Elbasvir wikiPageWikiLink Grazoprevir.
- Elbasvir wikiPageWikiLink Hepatitis_C.
- Elbasvir wikiPageWikiLink Hepatitis_C_virus.
- Elbasvir wikiPageWikiLink MK-3682.
- Elbasvir wikiPageWikiLink Merck_&_Co..
- Elbasvir wikiPageWikiLink Ribavirin.
- Elbasvir wikiPageWikiLinkText "Elbasvir".
- Elbasvir wikiPageWikiLinkText "elbasvir".
- Elbasvir c "49".
- Elbasvir casNumber "1370468".
- Elbasvir chemspiderid "30843797".
- Elbasvir h "55".
- Elbasvir inchi "1".
- Elbasvir inchikey "BVAZQCUMNICBAQ-PZHYSIFUBN".
- Elbasvir iupacName "Dimethyl N,N’-biscarbamate".
- Elbasvir legalStatus "Investigational".
- Elbasvir molecularWeight "882.015".
- Elbasvir n "9".
- Elbasvir o "7".
- Elbasvir routesOfAdministration "Oral".
- Elbasvir smiles "CC[C@@H]NCOC".
- Elbasvir stdinchi "1".
- Elbasvir stdinchikey "BVAZQCUMNICBAQ-PZHYSIFUSA-N".
- Elbasvir width "350".
- Elbasvir wikiPageUsesTemplate Template:Antiinfective-drug-stub.
- Elbasvir wikiPageUsesTemplate Template:Drugbox.
- Elbasvir wikiPageUsesTemplate Template:RNA_antivirals.
- Elbasvir wikiPageUsesTemplate Template:Reflist.
- Elbasvir subject Category:Anti-hepatitis_C_agents.
- Elbasvir subject Category:Carbamates.
- Elbasvir subject Category:Imidazoles.
- Elbasvir subject Category:Pyrrolidines.
- Elbasvir hypernym Drug.
- Elbasvir type ChemicalSubstance.
- Elbasvir type Drug.
- Elbasvir type ChemicalObject.
- Elbasvir type Thing.
- Elbasvir type Q8386.
- Elbasvir comment "Elbasvir (MK-8742) is a drug approved for the treatment of hepatitis C. It was developed by Merck and completed Phase III trials, following promising results in Phase II when used in combination with the NS3/4a protease inhibitor grazoprevir, either with or without ribavirin.Elbasvir is a highly potent and selective inhibitor of the hepatitis C virus NS5a replication complex.".
- Elbasvir label "Elbasvir".
- Elbasvir sameAs Q19904043.
- Elbasvir sameAs m.0131jxs9.
- Elbasvir sameAs Q19904043.
- Elbasvir wasDerivedFrom Elbasvir?oldid=702599134.
- Elbasvir depiction Elbasvir.svg.
- Elbasvir isPrimaryTopicOf Elbasvir.