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- Egg_lysin abstract "Egg lysin is a protein that creates a hole in the envelope of the egg thereby allowing the sperm to pass through the envelope and fuse with the egg. Fertilization proteins are acrosomal proteins involved in various roles during the fertilization process. Structurally these proteins consist of a closed bundle of helices with a right-hand twist. Lysin and SP18, both characterised in abalone, are two evolutionarily related fertilization proteins that have distinctive roles. Following its release from sperm, lysin binds to the egg vitelline envelope (VE) via the VE receptor for lysin (VERL), then non-enzymatically dissolves the VE to create a hole, thereby allowing the sperm to pass through the envelope and fuse with the egg. Lysins exhibit species-specific binding to their egg receptor, possibly through differences in charged surface residues. SP18 is also released from sperm, acting as a potent fusagen of liposomes to mediate the fusion between the sperm and egg cell membranes. Despite a similarity in the overall fold, the variation in the surface features of SP18 and lysin account for their different roles in fertilization.".
- Egg_lysin symbol "Egg_lysin".
- Egg_lysin wikiPageID "32046122".
- Egg_lysin wikiPageLength "2742".
- Egg_lysin wikiPageOutDegree "9".
- Egg_lysin wikiPageRevisionID "646548283".
- Egg_lysin wikiPageWikiLink Abalone.
- Egg_lysin wikiPageWikiLink Acrosome.
- Egg_lysin wikiPageWikiLink Category:Membrane_proteins.
- Egg_lysin wikiPageWikiLink Category:Protein_domains.
- Egg_lysin wikiPageWikiLink Egg.
- Egg_lysin wikiPageWikiLink Fertilisation.
- Egg_lysin wikiPageWikiLink Protein.
- Egg_lysin wikiPageWikiLink Sperm.
- Egg_lysin wikiPageWikiLink Vitelline_membrane.
- Egg_lysin wikiPageWikiLinkText "Egg lysin".
- Egg_lysin cdd "cd00243".
- Egg_lysin interpro "IPR001379".
- Egg_lysin name "Egg lysin".
- Egg_lysin pdb ":22-150 B:19-150 A:19-150 B:28-150 B:19-150".
- Egg_lysin pfam "PF01303".
- Egg_lysin scop "1".
- Egg_lysin symbol "Egg_lysin".
- Egg_lysin wikiPageUsesTemplate Template:InterPro_content.
- Egg_lysin wikiPageUsesTemplate Template:Orphan.
- Egg_lysin wikiPageUsesTemplate Template:PDB3.
- Egg_lysin wikiPageUsesTemplate Template:Pfam_box.
- Egg_lysin wikiPageUsesTemplate Template:Reflist.
- Egg_lysin subject Category:Membrane_proteins.
- Egg_lysin subject Category:Protein_domains.
- Egg_lysin hypernym Protein.
- Egg_lysin type Biomolecule.
- Egg_lysin type Protein.
- Egg_lysin type Domain.
- Egg_lysin type Thing.
- Egg_lysin type Q206229.
- Egg_lysin type Q8054.
- Egg_lysin comment "Egg lysin is a protein that creates a hole in the envelope of the egg thereby allowing the sperm to pass through the envelope and fuse with the egg. Fertilization proteins are acrosomal proteins involved in various roles during the fertilization process. Structurally these proteins consist of a closed bundle of helices with a right-hand twist. Lysin and SP18, both characterised in abalone, are two evolutionarily related fertilization proteins that have distinctive roles.".
- Egg_lysin label "Egg lysin".
- Egg_lysin sameAs Q5347847.
- Egg_lysin sameAs m.0gx284m.
- Egg_lysin sameAs Q5347847.
- Egg_lysin wasDerivedFrom Egg_lysin?oldid=646548283.
- Egg_lysin isPrimaryTopicOf Egg_lysin.