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- EPH_receptor_A4 abstract "EPH receptor A4 (ephrin type-A receptor 4) is a protein that in humans is encoded by the EPHA4 gene.This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.In 2012, a publication in Nature medicine revealed a connection between EPHA4 and the neurodegenerative disease Amyotrophic lateral sclerosis (ALS), where a defective gene allows ALS patients to live considerably longer than patients with an intact gene. This opens up for development of treatment for this, currently untreatable, disease.".
- EPH_receptor_A4 entrezgene "2043".
- EPH_receptor_A4 wikiPageID "14755739".
- EPH_receptor_A4 wikiPageLength "6450".
- EPH_receptor_A4 wikiPageOutDegree "3".
- EPH_receptor_A4 wikiPageRevisionID "699224103".
- EPH_receptor_A4 wikiPageWikiLink Category:Tyrosine_kinase_receptors.
- EPH_receptor_A4 wikiPageWikiLink Gene.
- EPH_receptor_A4 wikiPageWikiLink Protein.
- EPH_receptor_A4 wikiPageWikiLinkText "EPH receptor A4".
- EPH_receptor_A4 wikiPageWikiLinkText "EphA4".
- EPH_receptor_A4 requireManualInspection "no".
- EPH_receptor_A4 summaryText "This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. In 2012, a publication in Nature medicine revealed a connection between EPHA4 and the neurodegenerative disease Amyotrophic lateral sclerosis , where a defective gene allows ALS patients to live considerably longer than patients with an intact gene. This opens up for development of treatment for this, currently untreatable, disease.".
- EPH_receptor_A4 updateCitations "yes".
- EPH_receptor_A4 updatePage "yes".
- EPH_receptor_A4 updateProteinBox "yes".
- EPH_receptor_A4 updateSummary "yes".
- EPH_receptor_A4 wikiPageUsesTemplate Template:Cite_journal.
- EPH_receptor_A4 wikiPageUsesTemplate Template:Enzymes.
- EPH_receptor_A4 wikiPageUsesTemplate Template:Gene-2-stub.
- EPH_receptor_A4 wikiPageUsesTemplate Template:PBB.
- EPH_receptor_A4 wikiPageUsesTemplate Template:PBB_Controls.
- EPH_receptor_A4 wikiPageUsesTemplate Template:PBB_Further_reading.
- EPH_receptor_A4 wikiPageUsesTemplate Template:PBB_Summary.
- EPH_receptor_A4 wikiPageUsesTemplate Template:PDB_Gallery.
- EPH_receptor_A4 wikiPageUsesTemplate Template:Portal_bar.
- EPH_receptor_A4 wikiPageUsesTemplate Template:Refbegin.
- EPH_receptor_A4 wikiPageUsesTemplate Template:Refend.
- EPH_receptor_A4 wikiPageUsesTemplate Template:Reflist.
- EPH_receptor_A4 wikiPageUsesTemplate Template:Tyrosine_kinases.
- EPH_receptor_A4 subject Category:Tyrosine_kinase_receptors.
- EPH_receptor_A4 hypernym Protein.
- EPH_receptor_A4 type Biomolecule.
- EPH_receptor_A4 type Protein.
- EPH_receptor_A4 type Thing.
- EPH_receptor_A4 type Q206229.
- EPH_receptor_A4 type Q8054.
- EPH_receptor_A4 comment "EPH receptor A4 (ephrin type-A receptor 4) is a protein that in humans is encoded by the EPHA4 gene.This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats.".
- EPH_receptor_A4 label "EPH receptor A4".
- EPH_receptor_A4 sameAs Q18250397.
- EPH_receptor_A4 sameAs m.03gwtpm.
- EPH_receptor_A4 sameAs EPH_receptor_A4.
- EPH_receptor_A4 sameAs Q18250397.
- EPH_receptor_A4 wasDerivedFrom EPH_receptor_A4?oldid=699224103.
- EPH_receptor_A4 isPrimaryTopicOf EPH_receptor_A4.