Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/EDARADD> ?p ?o }
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- EDARADD abstract "Ectodysplasin-A receptor-associated adapter protein is a protein that in humans is encoded by the EDARADD gene.This gene was identified by its association with ectodermal dysplasia,and specifically with hypohidrotic ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.".
- EDARADD entrezgene "128178".
- EDARADD wikiPageExternalLink NBK1112.
- EDARADD wikiPageID "16846340".
- EDARADD wikiPageLength "5199".
- EDARADD wikiPageOutDegree "6".
- EDARADD wikiPageRevisionID "661010689".
- EDARADD wikiPageWikiLink Ectodermal_dysplasia.
- EDARADD wikiPageWikiLink Gene.
- EDARADD wikiPageWikiLink Hypohidrotic_ectodermal_dysplasia.
- EDARADD wikiPageWikiLink Protein.
- EDARADD wikiPageWikiLink Protein–protein_interaction.
- EDARADD wikiPageWikiLink TRAF2.
- EDARADD wikiPageWikiLinkText "EDARADD".
- EDARADD requireManualInspection "no".
- EDARADD summaryText "This gene was identified by its association with ectodermal dysplasia,and specifically with hypohidrotic ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.".
- EDARADD updateCitations "yes".
- EDARADD updatePage "yes".
- EDARADD updateProteinBox "yes".
- EDARADD updateSummary "yes".
- EDARADD wikiPageUsesTemplate Template:Cite_journal.
- EDARADD wikiPageUsesTemplate Template:Gene-1-stub.
- EDARADD wikiPageUsesTemplate Template:Intracellular_signaling_peptides_and_proteins.
- EDARADD wikiPageUsesTemplate Template:PBB.
- EDARADD wikiPageUsesTemplate Template:PBB_Controls.
- EDARADD wikiPageUsesTemplate Template:PBB_Further_reading.
- EDARADD wikiPageUsesTemplate Template:PBB_Summary.
- EDARADD wikiPageUsesTemplate Template:Refbegin.
- EDARADD wikiPageUsesTemplate Template:Refend.
- EDARADD wikiPageUsesTemplate Template:Reflist.
- EDARADD hypernym Protein.
- EDARADD type Biomolecule.
- EDARADD type Protein.
- EDARADD type Thing.
- EDARADD type Q206229.
- EDARADD type Q8054.
- EDARADD comment "Ectodysplasin-A receptor-associated adapter protein is a protein that in humans is encoded by the EDARADD gene.This gene was identified by its association with ectodermal dysplasia,and specifically with hypohidrotic ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands.".
- EDARADD label "EDARADD".
- EDARADD sameAs Q18049853.
- EDARADD sameAs m.0408474.
- EDARADD sameAs Q18049853.
- EDARADD wasDerivedFrom EDARADD?oldid=661010689.
- EDARADD isPrimaryTopicOf EDARADD.